CR20190574A - Ensayos de diagnóstico para detectar, cuantificar y/o rastrear microbios y otros analitos - Google Patents

Ensayos de diagnóstico para detectar, cuantificar y/o rastrear microbios y otros analitos

Info

Publication number
CR20190574A
CR20190574A CR20190574A CR20190574A CR20190574A CR 20190574 A CR20190574 A CR 20190574A CR 20190574 A CR20190574 A CR 20190574A CR 20190574 A CR20190574 A CR 20190574A CR 20190574 A CR20190574 A CR 20190574A
Authority
CR
Costa Rica
Prior art keywords
analytes
microbes
quantifying
tracking
detecting
Prior art date
Application number
CR20190574A
Other languages
English (en)
Inventor
Josh Collins
Scott Alan Shibata
Paul Zorner
Howard Bell
Eric J Mathur
Original Assignee
Locus Agriculture Ip Co Llc
Intelligent Mat Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Locus Agriculture Ip Co Llc, Intelligent Mat Solutions Inc filed Critical Locus Agriculture Ip Co Llc
Publication of CR20190574A publication Critical patent/CR20190574A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18—Water
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/155—Particles of a defined size, e.g. nanoparticles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Nanotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Luminescent Compositions (AREA)

Abstract

La presente invención proporciona métodos y ensayos para la detección multiplexada de analitos usando nanocristales que son uniformes en morfología, tamaño y composición en función de sus características ópticas únicas. Los métodos y ensayos descritos son particularmente útiles para la detección de microbios y/o agentes a base de microbios en una muestra ambiental compleja.
CR20190574A 2017-05-18 2018-05-17 Ensayos de diagnóstico para detectar, cuantificar y/o rastrear microbios y otros analitos CR20190574A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762507895P 2017-05-18 2017-05-18
PCT/US2018/033222 WO2018213604A2 (en) 2017-05-18 2018-05-17 Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes

Publications (1)

Publication Number Publication Date
CR20190574A true CR20190574A (es) 2020-04-03

Family

ID=64274881

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20190574A CR20190574A (es) 2017-05-18 2018-05-17 Ensayos de diagnóstico para detectar, cuantificar y/o rastrear microbios y otros analitos

Country Status (17)

Country Link
US (2) US20200102602A1 (es)
EP (1) EP3625563A4 (es)
JP (1) JP2020521127A (es)
KR (1) KR20200011456A (es)
CN (1) CN111051884A (es)
AU (1) AU2018269715A1 (es)
BR (1) BR112019024200A2 (es)
CA (1) CA3063714A1 (es)
CL (1) CL2019003286A1 (es)
CO (1) CO2019012771A2 (es)
CR (1) CR20190574A (es)
EA (1) EA201992748A1 (es)
MX (1) MX2019013724A (es)
PE (1) PE20200479A1 (es)
PH (1) PH12019502558A1 (es)
WO (1) WO2018213604A2 (es)
ZA (1) ZA201907514B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102732756B1 (ko) 2018-05-08 2024-11-22 로커스 애그리컬쳐 아이피 컴퍼니 엘엘씨 식물 뿌리 및 면역 건강을 증진시키기 위한 미생물-기반 제품
US12590339B2 (en) 2019-05-28 2026-03-31 Cz Biohub Sf, Llc Method for multiplexed detection of nucleic acids using spectrally encoded beads
WO2021007482A1 (en) * 2019-07-11 2021-01-14 Locus Agriculture Ip Company, Llc Use of soil and other environmental data to recommend customized agronomic programs
KR102388753B1 (ko) 2020-07-20 2022-04-20 광주과학기술원 유전영동 힘을 이용한 미생물 검출 장치
US20230288337A1 (en) * 2020-08-04 2023-09-14 University Of Technology Sydney High dimensional fingerprints of single nanoparticles and their use in multiplexed digital assays
CN112198133A (zh) * 2020-10-20 2021-01-08 上海洞舟实业有限公司 一种红外激光可视化检测仪的制备方法
CN112382510B (zh) * 2020-10-23 2022-07-05 华中科技大学 一种近红外光催化电极、制备方法及应用
KR102613085B1 (ko) 2020-11-26 2023-12-12 광주과학기술원 미생물 검출 시스템
CN112710845B (zh) * 2020-12-16 2023-07-07 北京热景生物技术股份有限公司 用于检测新冠状病毒中和抗体的试剂盒及检测方法
WO2022141230A1 (zh) * 2020-12-30 2022-07-07 北京化工大学 一种基于纳米金颗粒的多重核酸检测的方法
ES3043394T3 (en) * 2021-01-15 2025-11-25 Asahi Chemical Ind Method and kit for detecting presence and/or amount of bacteria in food/drink sample, environmental sample, or biological sample
KR102836698B1 (ko) 2022-01-25 2025-07-21 광주과학기술원 미지 용액내 미생물 농도 검출 소자
CN116042414B (zh) * 2023-01-04 2025-03-28 华中农业大学 一种灰色链霉菌h114及抑菌代谢物制备方法和应用
KR102853616B1 (ko) * 2024-01-03 2025-09-01 성균관대학교산학협력단 긴 분해시간을 갖는 고발광 생분해성 상향변환 나노프로브

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6207392B1 (en) * 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
EP1116036B1 (en) * 1998-09-18 2004-08-11 Massachusetts Institute Of Technology Water-soluble fluorescent semiconductor nanocrystals
US6274323B1 (en) * 1999-05-07 2001-08-14 Quantum Dot Corporation Method of detecting an analyte in a sample using semiconductor nanocrystals as a detectable label
US20020004246A1 (en) * 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
US20050208593A1 (en) * 2004-03-19 2005-09-22 Arizona Board Of Regents, Acting For And On Behalf Of Northern Arizona University Lateral flow diagnostic assay reader with radial cassette
EP1951888B1 (en) * 2005-11-09 2012-09-05 PrimeraDx, Inc. Multiplexed quantitative detection of pathogens
US20090047673A1 (en) * 2006-08-22 2009-02-19 Cary Robert B Miniaturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
KR20080030555A (ko) * 2007-12-04 2008-04-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 폴리머 코팅 시약을 포함하는 신규 수용성 나노크리스탈 및이의 제조방법
WO2009137055A1 (en) * 2008-05-05 2009-11-12 Los Alamos National Security, Llc Nanocrystal-based lateral flow microarrays and low-voltage signal detection systems
US7910309B2 (en) * 2008-07-31 2011-03-22 Los Alamos National Security, Llc Multiplexed lateral flow microarray assay for detection of citrus pathogens Xylella fastidiosa and Xanthomonas axonopodis pv citri
US10054593B2 (en) * 2015-06-05 2018-08-21 Intelleigent Material Solutions, Inc. Multiplexed spectral lifetime detection of phosphors
CN107916448B (zh) * 2010-12-28 2021-03-12 生命科技公司 使用有机配体的混合物制备纳米晶体
CN102199428B (zh) * 2011-04-11 2013-07-10 复旦大学 基于稀土掺杂的上转换纳米晶体的荧光编码微球及其制备方法
US20140170674A1 (en) * 2012-01-02 2014-06-19 Aimin He Membraine-Based Assay Devices Utilizing Time-Resolved Up-Converting Luminescence
SG10201500862RA (en) * 2014-02-04 2015-09-29 Agency Science Tech & Res A Method for Detecting a Target Analyte

Also Published As

Publication number Publication date
JP2020521127A (ja) 2020-07-16
CN111051884A (zh) 2020-04-21
EP3625563A4 (en) 2021-02-24
EP3625563A2 (en) 2020-03-25
CL2019003286A1 (es) 2020-07-24
KR20200011456A (ko) 2020-02-03
US20230025938A1 (en) 2023-01-26
CO2019012771A2 (es) 2020-04-01
MX2019013724A (es) 2020-07-20
US20200102602A1 (en) 2020-04-02
BR112019024200A2 (pt) 2020-06-02
AU2018269715A1 (en) 2020-01-16
PE20200479A1 (es) 2020-03-03
WO2018213604A2 (en) 2018-11-22
ZA201907514B (en) 2022-03-30
CA3063714A1 (en) 2018-11-22
PH12019502558A1 (en) 2021-01-25
EA201992748A1 (ru) 2020-03-16
WO2018213604A3 (en) 2018-12-27

Similar Documents

Publication Publication Date Title
PH12019502558A1 (en) Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes
ZA202000935B (en) Methods and materials for assessing and treating cancer
EP4464797A3 (en) Kit, device, and method for detecting lung cancer
EP4649966A3 (en) Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
MX2025004620A (es) Anticuerpos anti-lag3 radiomarcados para la obtencion de imagenes mediante inmuno-pet
MA40390A (fr) Procédés d'analyse impliquant des nanoparticules dissociables
WO2007114947A3 (en) Highly sensitive system and methods for analysis of troponin
MX2020010387A (es) Metodos para detectar y cuantificar fgf21.
EP4513499A3 (en) Method and device for analyzing target analyte in sample
WO2020243021A3 (en) Ntrk fusion molecules and uses thereof
MX376300B (es) Detección de factores de virulencia microbiana bucal.
MX2020006728A (es) Metodos para medir analito y/o proteina en muestras biologicas.
TW200745551A (en) Device and methods for detecting and quantifying one or more target agents
SG10201806729VA (en) Novel assay to detect human periostin
WO2012085574A3 (en) Detection of acute myeloid leukaemia
EP3922983A3 (en) Improved low sample volume urinalysis assay strip, analytical kits, and methods of use related thereto
EP4245374A3 (en) Pvrl2 and/or pvrig as biomarkers for treatment
MX2021003484A (es) Metodos para detectar efecto(s) hook asociado(s) con analito(s) de interes durante o que resulta(n) de la realizacion de ensayo(s) de diagnostico.
MX2021014335A (es) Metodos para detectar un nivel de h. pylori en una muestra fecal.
WO2022090801A3 (en) Pvrl2 and/or pvrig as biomarkers for treatment
EP4679093A3 (en) Methods of predicting progression of barrett's esophagus
WO2018119437A3 (en) Electrophoresis diagnostic methods and kits
BR112019005179A2 (pt) método e kit para analisar uma amostra
WO2016149316A8 (en) Systems, devices, and methods for threshold analyte calibration and quantitation using threshold analyte calibration
WO2020252381A3 (en) Anti-talen antibodies and uses thereof