CR20200058A - Gel comprising chlorhexidine - Google Patents
Gel comprising chlorhexidineInfo
- Publication number
- CR20200058A CR20200058A CR20200058A CR20200058A CR20200058A CR 20200058 A CR20200058 A CR 20200058A CR 20200058 A CR20200058 A CR 20200058A CR 20200058 A CR20200058 A CR 20200058A CR 20200058 A CR20200058 A CR 20200058A
- Authority
- CR
- Costa Rica
- Prior art keywords
- chlorhexidine
- gels
- pharmaceutically acceptable
- acceptable salt
- oral cavity
- Prior art date
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003260 chlorhexidine Drugs 0.000 title abstract 2
- 239000000499 gel Substances 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a gel composition comprising chlorhexidine and/or a pharmaceutically acceptable salt thereof; hyaluronic acid and/or a pharmaceutically acceptable salt thereof; and a gelling matrix, wherein the gelling matrix comprises water, and cellulose derivatives. The invention also relates to a method for preparing the gels and to particular uses of the gels in the field of oral cavity cosmetics, hygiene, prevention of oral cavity diseases and treatment of said diseases.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17382547 | 2017-08-04 | ||
| IE20170230A IE87094B1 (en) | 2017-08-04 | 2017-11-02 | Gel comprising chlorhexidine |
| PCT/EP2018/071155 WO2019025599A1 (en) | 2017-08-04 | 2018-08-03 | Gel comprising chlorhexidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20200058A true CR20200058A (en) | 2020-03-28 |
Family
ID=63047391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20200058A CR20200058A (en) | 2017-08-04 | 2018-08-03 | Gel comprising chlorhexidine |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3661480A1 (en) |
| CN (1) | CN110996891B (en) |
| BR (1) | BR112020002106B1 (en) |
| CL (1) | CL2020000293A1 (en) |
| CR (1) | CR20200058A (en) |
| IE (1) | IE87094B1 (en) |
| MX (1) | MX2020001363A (en) |
| NI (1) | NI202000007A (en) |
| PE (1) | PE20200698A1 (en) |
| PH (1) | PH12020550032A1 (en) |
| WO (1) | WO2019025599A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022538521A (en) | 2019-06-14 | 2022-09-05 | ザ プロクター アンド ギャンブル カンパニー | Leave-in oral care composition |
| MX2021015126A (en) | 2019-06-14 | 2022-01-24 | Procter & Gamble | Leave-on oral care compositions. |
| WO2020248232A1 (en) * | 2019-06-14 | 2020-12-17 | The Procter & Gamble Company | Leave-on oral care compositions |
| WO2020248239A1 (en) | 2019-06-14 | 2020-12-17 | The Procter & Gamble Company | Leave-on oral care compositions |
| EP3982917A1 (en) | 2019-06-14 | 2022-04-20 | The Procter & Gamble Company | Leave-on oral care compositions |
| CN111494376A (en) * | 2020-06-15 | 2020-08-07 | 牡丹江医学院 | Medicine for treating gingivitis and preparation method thereof |
| IT202000029288A1 (en) * | 2020-12-01 | 2022-06-01 | Altergon Sa | BIGUANIDINE MICROBIOCIDE SALTS WITH GLYCOSAMINOGLYCANS |
| CA3218883A1 (en) * | 2021-05-26 | 2022-12-01 | Murilo Nogueira NAKAJIMA | Oral care compositions |
| CN113440441B (en) * | 2021-07-29 | 2022-09-16 | 山东福瑞达生物股份有限公司 | Oral bacteriostatic composition containing essential oil and preparation method thereof |
| EP4483889A1 (en) | 2023-06-28 | 2025-01-01 | Igen Biolab Group AG | Postbiotic composition for oral administration for preventing or treating oral dysbiosis |
| GR1010853B (en) * | 2023-11-10 | 2025-01-10 | Ιουλια Τσετη | Composition of sodium hyaluronate and sucralphate for administration into the oral cavity |
| CN119033680A (en) * | 2024-08-28 | 2024-11-29 | 西南医科大学附属口腔医院 | Preparation method and application of hydrogel for oral mucosa injury |
| CN120309762B (en) * | 2025-04-29 | 2026-01-06 | 杭州三言生物科技有限公司 | A method for preparing chlorhexidine hyaluronic acid with antibacterial properties |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192802A (en) | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
| CH691030A5 (en) | 1995-09-26 | 2001-04-12 | Apr Applied Pharma Res Sa | A gel formulation, for topical use in the pharmaceutical, cosmetic, dietetic and veterinary industries |
| JPH1160505A (en) | 1997-05-20 | 1999-03-02 | Senju Pharmaceut Co Ltd | Antiseptic composition |
| US6117415A (en) | 1999-06-17 | 2000-09-12 | Alpharx Inc. | Toothpaste comprising bioadhesive submicron emulsion for improved delivery of antibacterial and anticaries agents |
| US8283135B2 (en) * | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| RU2286764C1 (en) | 2005-06-16 | 2006-11-10 | Георгий Георгиевич Ростиашвили | Agent of prolonged action for treatment of mouth cavity inflammation diseases |
| US8609634B2 (en) | 2007-05-16 | 2013-12-17 | Mcneil-Ppc, Inc. | Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods |
| US20090068122A1 (en) * | 2007-09-06 | 2009-03-12 | Shira Pilch | Dentifrice Compositions for Treating Xerostomia |
| EP2520279A1 (en) * | 2011-05-02 | 2012-11-07 | TERES S.r.l. | Thermoreversible gel pharamaceutical compositions for odontoiatric use |
| CN104474582A (en) * | 2014-12-17 | 2015-04-01 | 安徽省健源医疗器械设备有限公司 | Hyaluronic-acid-containing hemostatic gauze and preparation method thereof |
| PL3171854T3 (en) * | 2015-05-08 | 2020-11-02 | Curasept Ads S.R.L. | Improved mouthwash preparation |
| CN105342939A (en) * | 2015-12-15 | 2016-02-24 | 山东消博士消毒科技股份有限公司 | Disinfectant bath wash capable of reducing operative incision infection and preparation technology of disinfectant bath wash |
| CN106540281A (en) * | 2016-12-08 | 2017-03-29 | 邓丽萍 | B ultrasonic couplant and its preparation technology |
-
2017
- 2017-11-02 IE IE20170230A patent/IE87094B1/en unknown
-
2018
- 2018-08-03 PE PE2020000181A patent/PE20200698A1/en unknown
- 2018-08-03 BR BR112020002106-7A patent/BR112020002106B1/en active IP Right Grant
- 2018-08-03 MX MX2020001363A patent/MX2020001363A/en unknown
- 2018-08-03 CN CN201880052414.5A patent/CN110996891B/en active Active
- 2018-08-03 EP EP18746958.0A patent/EP3661480A1/en active Pending
- 2018-08-03 CR CR20200058A patent/CR20200058A/en unknown
- 2018-08-03 WO PCT/EP2018/071155 patent/WO2019025599A1/en not_active Ceased
-
2020
- 2020-01-21 PH PH12020550032A patent/PH12020550032A1/en unknown
- 2020-01-28 NI NI202000007A patent/NI202000007A/en unknown
- 2020-01-31 CL CL2020000293A patent/CL2020000293A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3661480A1 (en) | 2020-06-10 |
| CL2020000293A1 (en) | 2020-08-14 |
| WO2019025599A1 (en) | 2019-02-07 |
| PE20200698A1 (en) | 2020-06-16 |
| CN110996891B (en) | 2023-02-28 |
| BR112020002106A8 (en) | 2020-12-01 |
| NI202000007A (en) | 2020-07-31 |
| PH12020550032A1 (en) | 2021-02-15 |
| BR112020002106A2 (en) | 2020-08-04 |
| IE87094B1 (en) | 2020-05-13 |
| MX2020001363A (en) | 2020-03-20 |
| CN110996891A (en) | 2020-04-10 |
| IE20170230A1 (en) | 2019-02-06 |
| BR112020002106B1 (en) | 2023-04-18 |
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