CR20230257A - Ésteres de ácidos dicarboxílicos para el tratamiento de enfermedades y padecimientos asociados con la toxina fosfolipasa d - Google Patents

Ésteres de ácidos dicarboxílicos para el tratamiento de enfermedades y padecimientos asociados con la toxina fosfolipasa d

Info

Publication number
CR20230257A
CR20230257A CR20230257A CR20230257A CR20230257A CR 20230257 A CR20230257 A CR 20230257A CR 20230257 A CR20230257 A CR 20230257A CR 20230257 A CR20230257 A CR 20230257A CR 20230257 A CR20230257 A CR 20230257A
Authority
CR
Costa Rica
Prior art keywords
inducing
dicarboxylic acid
analgesic effect
acid esters
methods
Prior art date
Application number
CR20230257A
Other languages
English (en)
Inventor
Elzbieta Izbicka
Robert T Streeper
Original Assignee
New Frontier Labs Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Frontier Labs Llc filed Critical New Frontier Labs Llc
Publication of CR20230257A publication Critical patent/CR20230257A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La divulgación provee composiciones y métodos de tratamiento de enfermedades y padecimientos asociados con la toxina fosfolipasa D (PLD). En particular, los métodos incluyen la administración, a un sujeto en necesidad, de una composición farmacéutica que comprende un éster de ácido dicarboxílico
CR20230257A 2020-12-16 2021-12-16 Ésteres de ácidos dicarboxílicos para el tratamiento de enfermedades y padecimientos asociados con la toxina fosfolipasa d CR20230257A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063126374P 2020-12-16 2020-12-16
PCT/IB2021/061874 WO2022130290A1 (en) 2020-12-16 2021-12-16 Dicarboxylic acid esters for the treatment of diseases and conditions associated with phospholipase d toxin

Publications (1)

Publication Number Publication Date
CR20230257A true CR20230257A (es) 2023-10-11

Family

ID=81942875

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20230257A CR20230257A (es) 2020-12-16 2021-12-16 Ésteres de ácidos dicarboxílicos para el tratamiento de enfermedades y padecimientos asociados con la toxina fosfolipasa d

Country Status (9)

Country Link
US (1) US11918555B2 (es)
EP (1) EP4262780A4 (es)
CL (1) CL2023001739A1 (es)
CO (1) CO2023007955A2 (es)
CR (1) CR20230257A (es)
EC (1) ECSP23052429A (es)
MX (1) MX2023006727A (es)
PE (1) PE20232040A1 (es)
WO (1) WO2022130290A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20260048034A1 (en) 2024-08-15 2026-02-19 New Frontier Labs, Llc Compositions and methods for enhancing the efficacy of dicarboxylic acid esters, and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2523428B2 (ja) * 1992-12-04 1996-08-07 エスエス製薬株式会社 消炎鎮痛ゲル製剤
US9265725B2 (en) * 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
JP2004300113A (ja) * 2003-04-01 2004-10-28 Nichiban Co Ltd 消炎鎮痛貼付剤
WO2006074379A2 (en) * 2005-01-07 2006-07-13 Azaya Therapeutics, Inc. Methods and compositions involving esters of azelaic acid and other dicarboxylic acids
JP2007055988A (ja) 2005-08-23 2007-03-08 Mayumi Hirozawa スーパー虫さされ治療薬
RS55769B1 (sr) * 2007-11-23 2017-07-31 Gruenenthal Gmbh Kompozicije tapentadola
US8404260B2 (en) * 2008-04-02 2013-03-26 Bayer Cropscience Lp Synergistic pesticide compositions
WO2010005521A1 (en) * 2008-06-30 2010-01-14 Bltn, Llc Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers
US20120251525A1 (en) * 2009-06-30 2012-10-04 Streeper Robert T Method of utilizing azelaic acid esters to modulate communications mediated by biological molecules
EP2750680B1 (en) 2011-08-29 2018-12-26 Orna Levin Composition for treating lice infestation
BR102013031043B1 (pt) 2013-12-02 2018-03-13 Fundação Butantan Uso de compostos químicos capazes de inibir a ação tóxica das esfingomielinases d do veneno de aranhas loxosceles e composição farmacêutica compreendendo os referidos compostos
CN103734134B (zh) * 2014-01-26 2016-04-20 上海艳紫化工科技有限公司 乙基多杀菌素和杀虫单复配的油悬浮剂
SG11201808367UA (en) * 2016-04-20 2018-10-30 New Frontier Labs Llc Azelaic acid esters in the treatment of insulin resistance
JPWO2020130084A1 (ja) * 2018-12-19 2021-11-04 株式会社 メドレックス 消炎鎮痛外用剤

Also Published As

Publication number Publication date
MX2023006727A (es) 2023-06-26
WO2022130290A1 (en) 2022-06-23
US20220184024A1 (en) 2022-06-16
CO2023007955A2 (es) 2023-06-30
EP4262780A4 (en) 2024-11-13
PE20232040A1 (es) 2023-12-21
EP4262780A1 (en) 2023-10-25
ECSP23052429A (es) 2023-08-31
CL2023001739A1 (es) 2024-01-19
US11918555B2 (en) 2024-03-05

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