CR20240023A - Compuestos de sulfonimidamida y usos de los mismos - Google Patents

Compuestos de sulfonimidamida y usos de los mismos

Info

Publication number
CR20240023A
CR20240023A CR20240023A CR20240023A CR20240023A CR 20240023 A CR20240023 A CR 20240023A CR 20240023 A CR20240023 A CR 20240023A CR 20240023 A CR20240023 A CR 20240023A CR 20240023 A CR20240023 A CR 20240023A
Authority
CR
Costa Rica
Prior art keywords
compounds
sulfonimidamde
tautomers
solvates
pharmaceutically acceptable
Prior art date
Application number
CR20240023A
Other languages
English (en)
Inventor
Kwong Wah Lai
Christian Nilewski
Craig Stivala
Richard M Pastor
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CR20240023A publication Critical patent/CR20240023A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En el presente documento se describen compuestos de sulfonimidamida, solvatos de los mismos, tautómeros de los mismos y sales farmacéuticamente aceptables de los anteriores. Además, en el presente documento se describen procedimientos para tratar un trastorno en un sujeto que necesite de los mismos usando dichos compuestos, solvatos, tautómeros, o sales farmacéuticamente aceptables de los mismos, tales como trastornos mediados por NLRP3.
CR20240023A 2021-07-19 2022-07-15 Compuestos de sulfonimidamida y usos de los mismos CR20240023A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2021107085 2021-07-19
CN2022077518 2022-02-23
PCT/US2022/073756 WO2023004257A1 (en) 2021-07-19 2022-07-15 Sulfonimidamde compounds and uses thereof

Publications (1)

Publication Number Publication Date
CR20240023A true CR20240023A (es) 2024-02-13

Family

ID=82899213

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20240023A CR20240023A (es) 2021-07-19 2022-07-15 Compuestos de sulfonimidamida y usos de los mismos

Country Status (16)

Country Link
US (1) US20240336625A1 (es)
EP (1) EP4373826A1 (es)
JP (1) JP2024528656A (es)
KR (1) KR20240037240A (es)
CN (1) CN117677622A (es)
AR (1) AR126474A1 (es)
AU (1) AU2022314729A1 (es)
CA (1) CA3222454A1 (es)
CL (1) CL2024000125A1 (es)
CO (1) CO2024001004A2 (es)
CR (1) CR20240023A (es)
IL (1) IL308461A (es)
MX (1) MX2024000634A (es)
PE (1) PE20240246A1 (es)
TW (1) TW202321262A (es)
WO (1) WO2023004257A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025153532A1 (en) 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies
CN119100956B (zh) * 2024-09-03 2025-12-02 大连理工大学 一种无催化剂的光驱动合成亚磺酰胺类化合物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021001044A2 (pt) * 2018-07-20 2021-04-13 F. Hoffmann-La Roche Ag Compostos de sulfonimidamida como inibidores da atividade de interleucina-1
JP7843705B2 (ja) * 2020-01-22 2026-04-10 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト Nlrp3モジュレーターとしてのスルホンイミドアミド化合物

Also Published As

Publication number Publication date
AR126474A1 (es) 2023-10-11
WO2023004257A1 (en) 2023-01-26
IL308461A (en) 2024-01-01
CN117677622A (zh) 2024-03-08
MX2024000634A (es) 2024-02-13
JP2024528656A (ja) 2024-07-30
PE20240246A1 (es) 2024-02-19
AU2022314729A1 (en) 2023-11-30
CL2024000125A1 (es) 2024-08-23
KR20240037240A (ko) 2024-03-21
EP4373826A1 (en) 2024-05-29
TW202321262A (zh) 2023-06-01
CA3222454A1 (en) 2023-01-26
CO2024001004A2 (es) 2024-02-26
US20240336625A1 (en) 2024-10-10

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