CR20240139A - Anticuerpos del receptor antitransferrina y usos de los mismos - Google Patents

Anticuerpos del receptor antitransferrina y usos de los mismos

Info

Publication number
CR20240139A
CR20240139A CR20240139A CR20240139A CR20240139A CR 20240139 A CR20240139 A CR 20240139A CR 20240139 A CR20240139 A CR 20240139A CR 20240139 A CR20240139 A CR 20240139A CR 20240139 A CR20240139 A CR 20240139A
Authority
CR
Costa Rica
Prior art keywords
transferrin receptor
receptor antibodies
antibodies
methods
same
Prior art date
Application number
CR20240139A
Other languages
English (en)
Inventor
Karl J M Hanf
Isin Dalkilic-Liddle
R Blake Pepinsky
Benjamin A Smith
Fang Qian
Thomas O Cameron
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Publication of CR20240139A publication Critical patent/CR20240139A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2881—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente descripción proporciona anticuerpos del receptor antitransferrina, composiciones que los comprenden y métodos para su uso. Esta descripción también proporciona polinucleótidos y vectores que codifican los anticuerpos del receptor antitransferrina y las células que comprenden los mismos, los métodos para producir los anticuerpos y las moléculas que comprenden los anticuerpos.
CR20240139A 2021-09-01 2022-08-31 Anticuerpos del receptor antitransferrina y usos de los mismos CR20240139A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163239630P 2021-09-01 2021-09-01
US202263388088P 2022-07-11 2022-07-11
PCT/US2022/042196 WO2023034409A1 (en) 2021-09-01 2022-08-31 Anti-transferrin receptor antibodies and uses thereof

Publications (1)

Publication Number Publication Date
CR20240139A true CR20240139A (es) 2024-06-14

Family

ID=83508506

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20240139A CR20240139A (es) 2021-09-01 2022-08-31 Anticuerpos del receptor antitransferrina y usos de los mismos

Country Status (15)

Country Link
US (2) US11827702B2 (es)
EP (1) EP4396231A1 (es)
JP (1) JP2024534880A (es)
KR (1) KR20240107202A (es)
AU (1) AU2022340568A1 (es)
CA (1) CA3230796A1 (es)
CL (1) CL2024000642A1 (es)
CO (1) CO2024003577A2 (es)
CR (1) CR20240139A (es)
IL (1) IL311175A (es)
JO (1) JOP20240042A1 (es)
MX (1) MX2024002753A (es)
PE (1) PE20240895A1 (es)
TW (1) TW202328187A (es)
WO (1) WO2023034409A1 (es)

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PE20260008A1 (es) 2023-03-08 2026-01-06 Biogen Ma Inc Anticuerpos anti-receptor de transferrina y usos de estos
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
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WO2025090898A1 (en) * 2023-10-26 2025-05-01 Biogen Ma Inc. Anti-transferrin receptor antibodies and uses thereof cross reference to related applications
WO2026076250A1 (en) * 2024-10-03 2026-04-09 Genentech, Inc. Lipid nanoparticles for delivery to the cns from systemic administration

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Also Published As

Publication number Publication date
PE20240895A1 (es) 2024-04-24
WO2023034409A1 (en) 2023-03-09
EP4396231A1 (en) 2024-07-10
US20240158494A1 (en) 2024-05-16
TW202328187A (zh) 2023-07-16
MX2024002753A (es) 2024-05-20
JP2024534880A (ja) 2024-09-26
AU2022340568A1 (en) 2024-03-28
US20230131379A1 (en) 2023-04-27
CL2024000642A1 (es) 2024-09-13
JOP20240042A1 (ar) 2024-02-29
US11827702B2 (en) 2023-11-28
CA3230796A1 (en) 2023-03-09
CO2024003577A2 (es) 2024-06-27
KR20240107202A (ko) 2024-07-08
IL311175A (en) 2024-04-01

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