CR6434A - Aminotransferasa dependiente de aminoacidos de cadena ramificada y su uso en el tratamiento de la retinopatia diabetica - Google Patents
Aminotransferasa dependiente de aminoacidos de cadena ramificada y su uso en el tratamiento de la retinopatia diabeticaInfo
- Publication number
- CR6434A CR6434A CR6434A CR6434A CR6434A CR 6434 A CR6434 A CR 6434A CR 6434 A CR6434 A CR 6434A CR 6434 A CR6434 A CR 6434A CR 6434 A CR6434 A CR 6434A
- Authority
- CR
- Costa Rica
- Prior art keywords
- diabetic retinopathy
- dependent
- treatment
- aminotranspherase
- amino acids
- Prior art date
Links
- 206010012689 Diabetic retinopathy Diseases 0.000 title abstract 4
- 230000001419 dependent effect Effects 0.000 title abstract 3
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 102000003929 Transaminases Human genes 0.000 abstract 2
- 108090000340 Transaminases Proteins 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000037361 pathway Effects 0.000 abstract 2
- 101710105312 Branched-chain-amino-acid aminotransferase Proteins 0.000 abstract 1
- 101710097328 Branched-chain-amino-acid aminotransferase, cytosolic Proteins 0.000 abstract 1
- 101710194298 Branched-chain-amino-acid aminotransferase, mitochondrial Proteins 0.000 abstract 1
- 206010018429 Glucose tolerance impaired Diseases 0.000 abstract 1
- 101710158343 Probable branched-chain-amino-acid aminotransferase Proteins 0.000 abstract 1
- 101710199693 Putative branched-chain-amino-acid aminotransferase Proteins 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 201000007917 background diabetic retinopathy Diseases 0.000 abstract 1
- AZPBDRUPTRGILK-UHFFFAOYSA-N benzotriazol-1-ium-1-ylidenemethanediamine;4-methylbenzenesulfonate Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1.C1=CC=C2N(C(=N)N)N=NC2=C1 AZPBDRUPTRGILK-UHFFFAOYSA-N 0.000 abstract 1
- 150000005693 branched-chain amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000007914 proliferative diabetic retinopathy Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se relaciona con un método para el tratamiento profiláctico y terapéutico de la retinopatía diabética, incluyendo el tratamiento en la etapa de la retinopatía prediabética, la etapa de la retinopatía diabética no proliferativa y la etapa de la retinopatía diabética proliferativa. El método comprende la administración de un inhibidor de la vía de la aminotransferasa dependiente de aminoácidos ramificados. Preferentemente, el inhibidor de la vía de la amino transferasa dependiente de los aminoácidos de cadena ramificada (BCAT) es un compuesto de las Fórmulas I, II y/o III.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16963599P | 1999-12-08 | 1999-12-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR6434A true CR6434A (es) | 2004-04-27 |
Family
ID=27757245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR6434A CR6434A (es) | 1999-12-08 | 2001-08-07 | Aminotransferasa dependiente de aminoacidos de cadena ramificada y su uso en el tratamiento de la retinopatia diabetica |
Country Status (2)
| Country | Link |
|---|---|
| CR (1) | CR6434A (es) |
| ZA (1) | ZA200106260B (es) |
-
2001
- 2001-07-30 ZA ZA200106260A patent/ZA200106260B/en unknown
- 2001-08-07 CR CR6434A patent/CR6434A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200106260B (en) | 2002-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |