CR8380A - Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos - Google Patents

Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos

Info

Publication number
CR8380A
CR8380A CR8380A CR8380A CR8380A CR 8380 A CR8380 A CR 8380A CR 8380 A CR8380 A CR 8380A CR 8380 A CR8380 A CR 8380A CR 8380 A CR8380 A CR 8380A
Authority
CR
Costa Rica
Prior art keywords
preparing
methods
assemblies
new developments
mother cells
Prior art date
Application number
CR8380A
Other languages
English (en)
Inventor
J Harman Robert
T Sand Theodore
Original Assignee
Vet Stem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34437753&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8380(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vet Stem Inc filed Critical Vet Stem Inc
Publication of CR8380A publication Critical patent/CR8380A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10Mechanical dissociation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)

Abstract

El presente invento introduce nvoedosos compuestos de celulas madre que presentan importantes ventajas terapeuticas y practicas; e introduce tambien metodos para preparar y utilizar dichos compuestos en pacientes para el tratamiento y la prevencion de lesiones y enfermedades.
CR8380A 2003-10-08 2006-05-04 Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos CR8380A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51002203P 2003-10-08 2003-10-08
US51002103P 2003-10-08 2003-10-08
US51007203P 2003-10-09 2003-10-09
US50992803P 2003-10-09 2003-10-09

Publications (1)

Publication Number Publication Date
CR8380A true CR8380A (es) 2009-02-10

Family

ID=34437753

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8380A CR8380A (es) 2003-10-08 2006-05-04 Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos

Country Status (9)

Country Link
US (5) US9453202B2 (es)
EP (2) EP1678295B1 (es)
JP (2) JP2007508018A (es)
AU (1) AU2004280616A1 (es)
CA (1) CA2542120C (es)
CR (1) CR8380A (es)
NZ (1) NZ597965A (es)
SG (1) SG146691A1 (es)
WO (1) WO2005035742A2 (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US20050048035A1 (en) 2001-12-07 2005-03-03 Fraser John K. Methods of using regenerative cells in the treatment of stroke and related diseases and disorders
US8404229B2 (en) 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
KR100930139B1 (ko) 2001-12-07 2009-12-07 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
JP2007508018A (ja) 2003-10-08 2007-04-05 べト−ステム インコーポレイテッド 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット
WO2006014159A2 (en) * 2004-07-01 2006-02-09 Macropore Biosurgery Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
WO2006062989A1 (en) * 2004-12-07 2006-06-15 Bacterin International, Inc. Three-dimensional cell culsture system
FR2902011B1 (fr) 2006-06-12 2008-12-26 Inst Radioprot Et De Surete Nu Utilisation de fractions cellulaires du tissu adipeux pour la regeneration tissulaire post irradiation
WO2008011524A2 (en) 2006-07-20 2008-01-24 Richard Burt Method of using mitotically inactivated stem cells for damaged tissue repair
CN101332315A (zh) * 2007-06-29 2008-12-31 上海国睿生命科技有限公司 组织工程肌腱及其体外构建方法
WO2009115581A2 (en) * 2008-03-19 2009-09-24 Cryo-Save Ag Improved cryopreservation of adipose tissue for the isolation of mesenchymal stem cells
WO2009152084A2 (en) * 2008-06-11 2009-12-17 Cell4Vet Llc Adipose tissue-derived stem cells for veterinary use
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
AU2009201915C1 (en) 2008-08-22 2015-02-26 Regeneus Ltd Therapeutic methods
AU2011247866B9 (en) * 2008-08-22 2014-02-13 Regeneus Ltd. Allogeneic therapeutic methods using adipose tissue-derived cell suspensions
US8309343B2 (en) 2008-12-01 2012-11-13 Baxter International Inc. Apparatus and method for processing biological material
US10328103B2 (en) 2009-01-03 2019-06-25 Ray C. Wasielewski Medical treatment composition comprising mammalian dental pulp stem cells
US8470308B2 (en) * 2009-01-03 2013-06-25 Ray C. Wasielewski Enhanced medical implant comprising disrupted tooth pulp and tooth particles
AU2010242780B2 (en) 2009-05-01 2016-04-21 Puregraft Llc Systems, methods and compositions for optimizing tissue and cell enriched grafts
US9867788B2 (en) * 2009-07-09 2018-01-16 Boston Scientific Scimed, Inc. Multi-chamber cellular mixing and delivery system and method
US10273457B2 (en) * 2010-04-14 2019-04-30 Massimo Dominici Method of obtaining a population of cells
IT1400069B1 (it) 2010-05-20 2013-05-17 Tremolada Dispositivo e metodo per la preparazione di tessuto, in particolare tessuto adiposo per trapianto ottenuto da materiale adiposo lobulare estratto tramite liposuzione
DE102010046218A1 (de) 2010-09-21 2012-03-22 Livlmplant Gmbh Zell-basiertes Injektionssystem zur Behandlung von Verletzungen
US20120156177A1 (en) * 2010-10-07 2012-06-21 Scarpone Michael A Methods and devices for harvesting and processing connective tissue precursor cells from autologous fat
HK1197262A1 (en) * 2011-02-18 2015-01-09 永生细胞公司 Stem cells packaging and shipping
EP3156060B1 (en) * 2011-03-15 2019-11-06 Cell Ideas Pty Ltd. Pharmaceutical compositions and topical use thereof
EP2686419B1 (en) 2011-03-18 2016-11-16 MicroVascular Tissues, Inc. Allogeneic microvascular tissue for soft tissue treatments
CA3205636A1 (en) * 2011-04-20 2012-10-26 University Of Washington Through Its Center For Commercialization Beta-2 microglobulin-deficient cells
EP2744892B1 (en) 2011-09-23 2019-03-20 Cell Ideas Pty Ltd. Therapeutics using adipose cells and cell secretions
AU2013205128A1 (en) * 2011-09-23 2013-05-16 Cell Ideas Pty Ltd Therapeutics using adipose cells and cell secretions
SG11201405875PA (en) 2012-03-19 2014-11-27 Richard Burt Methods and compositions for regenerating and repairing damaged tissue using nonviable irradiated or lyophilized pluripotent stem cells
ITGE20120034A1 (it) * 2012-03-28 2013-09-29 Carlo Tremolada Preparato e metodo per la produzione di un preparato comprendente cellule staminali mesenchimali
KR20150056522A (ko) * 2012-06-26 2015-05-26 앰버데일 엔터프라이지즈 피티와이 리미티드 초음파 공동화에 의한 지방 조직으로부터 줄기 세포의 분리 및 이의 이용 방법
JP2015521630A (ja) * 2012-06-26 2015-07-30 ラスティー プロパティー ホールディングス プロプライエタリー リミテッド 頭痛の頻度および/または重症度を下げるための組成物および方法
ITGE20120073A1 (it) 2012-07-23 2014-01-24 Carlo Tremolada Metodo e dispositivo per la preparazione di cellule staminali non embrionali
US11819522B2 (en) 2012-09-19 2023-11-21 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US10596202B2 (en) 2012-09-19 2020-03-24 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9713629B2 (en) 2012-09-19 2017-07-25 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9872937B2 (en) 2012-09-19 2018-01-23 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
TWI654983B (zh) * 2012-11-21 2019-04-01 瑟弗維股份有限公司 動物用之脂肪組織-衍生幹細胞
US9775864B2 (en) * 2013-01-31 2017-10-03 Ams Research Corporation Vaginal laxity therapy utilizing cell-based bulking compositions
MX2015014053A (es) * 2013-04-05 2016-04-07 Claudia Zylberberg Metaloproteinasas de matriz y sus usos.
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
US10813955B2 (en) 2015-09-29 2020-10-27 Genani Corporation Methods for treating age-related organ or tissue dysfunction through heterochronic transbiosis using nonviable pluripotent stem cells
US20180353549A1 (en) * 2015-12-04 2018-12-13 Vet-Stem, Inc. Compositions and method for treating and preventing bleeding and lung injuries and diseases
EP4324915A3 (en) 2016-03-17 2024-06-19 Synova Life Sciences, Inc. Separation, dissociation and/or disaggregation of cells using shockwaves or mechanical impacts
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
DE102016114043B3 (de) 2016-07-29 2017-08-10 Technische Universität Dresden Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben
JP6338259B1 (ja) * 2017-02-28 2018-06-06 学校法人昭和大学 半月板再生用材料及び半月板再生用材料の作製方法
JP6286094B1 (ja) * 2017-07-05 2018-02-28 セルソース株式会社 細胞組織を含む流動体のための剪断装置
JP7309194B2 (ja) * 2019-11-11 2023-07-18 株式会社金太郎CellsPower 幹細胞運搬方法

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868121A (en) 1985-02-07 1989-09-19 Mcdonnell Douglas Corporation Islet isolation process
US5079160A (en) 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
US5143063A (en) * 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6010696A (en) * 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5811094A (en) * 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5340740A (en) * 1992-05-15 1994-08-23 North Carolina State University Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
AU4543193A (en) * 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
US5422261A (en) 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
CA2192103C (en) * 1994-06-06 2002-02-05 Arnold I. Caplan Biomatrix for tissue regeneration
DE69534405T2 (de) 1994-07-01 2006-03-09 Edwards Lifesciences Corp., Irvine Vorrichtung zum gewinnen von autologen, mikrovaskulären endothelialen zellen enthaltendem fettgewebe
US5906934A (en) * 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US6974571B2 (en) * 1995-03-28 2005-12-13 Thomas Jefferson University Isolated stromal cells and methods of using the same
CA2237890C (en) * 1995-11-16 2011-03-29 Case Western Reserve University In vitro chondrogenic induction of human mesenchymal stem cells
US6482231B1 (en) * 1995-11-20 2002-11-19 Giovanni Abatangelo Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative
US6828144B2 (en) * 1996-04-09 2004-12-07 Wisconsin Alumni Research Foundation Method of observing vasculogenesis in vitro using cultured allantois
ATE439849T1 (de) * 1996-04-19 2009-09-15 Osiris Therapeutics Inc Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen
US6020196A (en) * 1996-05-09 2000-02-01 Baxter International Inc. Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells
US5827740A (en) * 1996-07-30 1998-10-27 Osiris Therapeutics, Inc. Adipogenic differentiation of human mesenchymal stem cells
ATE229810T1 (de) * 1996-10-11 2003-01-15 Univ California Krebs immuntherapie unter verwendung von tumorzellen kombiniert mit lymphozytmischungen
US5919702A (en) 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
CA2278539A1 (en) 1997-01-24 1998-07-30 Osiris Therapeutics, Inc. Bone regeneration in osteoporosis using human bone marrow mesenchymal cells
US5786207A (en) * 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
AU9127098A (en) * 1997-09-04 1999-03-22 Osiris Therapeutics, Inc. Ligands that modulate differentiation of mesenchymal stem cells
US5955257A (en) * 1997-10-21 1999-09-21 Regents Of The University Of Minnesota Infusible grade short-term cell storage medium for mononuclear cells
CN1166773C (zh) * 1997-12-02 2004-09-15 泽恩比奥公司 分离的人脂肪组织衍生的基质细胞
AU749675B2 (en) * 1998-03-13 2002-07-04 Mesoblast International Sarl Uses for human non-autologous mesenchymal stem cells
US6100047A (en) * 1999-04-07 2000-08-08 Zen Bio, Inc. Modulation of the sulfonylurea receptor and calcium in adipocytes for treatment of obesity/diabetes
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
AU4221399A (en) * 1998-05-29 1999-12-13 Osiris Therapeutics, Inc. Human cd45+ and/or fibroblast + mesenchymal stem cells
JP2003505006A (ja) * 1998-06-08 2003-02-12 オシリス セラピューティクス,インコーポレイテッド ヒト間葉幹細胞の使用による造血幹細胞分化の調節
US6302863B1 (en) 1998-06-16 2001-10-16 Nikolai Tankovich Method for removal of lipids via a perfluorocarbon tumescent solution
US6849255B2 (en) * 1998-08-18 2005-02-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for enhancing cartilage repair
US6184035B1 (en) * 1998-11-18 2001-02-06 California Institute Of Technology Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells
US6391348B1 (en) * 1998-11-20 2002-05-21 Pioneer Hi-Bred International, Inc. Method of reducing cholesterol in eggs
BR0007296A (pt) * 1999-01-04 2002-02-05 Biomm Inc Novas formulações poliméricas contendo compostos perfluorados para a engenharia de células e tecidos para transplantes que melhoram o metabolismo e a sobrevivência celular, e métodos para a sua produção
US6153432A (en) * 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
US6767738B1 (en) * 1999-02-11 2004-07-27 The Salk Institute For Biological Studies Method of isolating adult mammalian CNS-derived progenitor stem cells using density gradient centrifugation
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
KR100979664B1 (ko) 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
WO2002064748A2 (en) * 2001-02-14 2002-08-22 Furcht Leo T Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6555374B1 (en) * 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
WO2001021767A2 (en) * 1999-09-24 2001-03-29 Morphogen Pharmaceuticals, Inc. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
US7544509B2 (en) 2000-01-24 2009-06-09 Mcgill University Method for preparing stem cell preparations
US6610535B1 (en) * 2000-02-10 2003-08-26 Es Cell International Pte Ltd. Progenitor cells and methods and uses related thereto
EP1261694B1 (en) * 2000-02-26 2008-01-16 Artecel, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
AU5723601A (en) * 2000-04-25 2001-11-07 Osiris Therapeutics Inc Joint repair using mesenchymal stem cells
WO2001082901A1 (en) 2000-04-28 2001-11-08 Zengen, Inc. New antibodies to biological membranes
WO2001082991A2 (en) * 2000-05-03 2001-11-08 Fidia Advanced Biopolymers Srl Biomaterials comprised of preadipocyte cells for soft tissue repair
US7049072B2 (en) * 2000-06-05 2006-05-23 University Of South Florida Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state
US20040022787A1 (en) * 2000-07-03 2004-02-05 Robert Cohen Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
US6905886B2 (en) * 2000-08-11 2005-06-14 Quest Diagnostics Investments Incorporated Preservative solutions
US6607498B2 (en) * 2001-01-03 2003-08-19 Uitra Shape, Inc. Method and apparatus for non-invasive body contouring by lysing adipose tissue
FR2819265B1 (fr) * 2001-01-10 2004-01-02 Centre Nat Rech Scient Cellules du tissu adipeux extramedullaire et leurs applications dans la reconstitution des lignees hematopoietiques
AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
US20020155096A1 (en) * 2001-02-23 2002-10-24 Chancellor Michael B. Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
US20040152190A1 (en) * 2001-05-31 2004-08-05 Masaya Sumita Method of separating and concentrating cells for kidney regfneration
EP1423504B1 (en) * 2001-08-08 2009-09-23 Levesque Biosciences, Inc. Compositions and methods for isolation, propagation, and differentiation of non-embryonic human stem cells and uses thereof
US20030054331A1 (en) * 2001-09-14 2003-03-20 Stemsource, Inc. Preservation of non embryonic cells from non hematopoietic tissues
KR20090115984A (ko) * 2001-11-09 2009-11-10 아르테셀 사이언스, 인크. 지방 조직에서 유래된 기질세포의 내분비 췌장 분화 및 이의 용도
KR100930139B1 (ko) * 2001-12-07 2009-12-07 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
US20050008626A1 (en) * 2001-12-07 2005-01-13 Fraser John K. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
JP2003219873A (ja) * 2002-01-24 2003-08-05 Japan Science & Technology Corp サケ科キングサーモン由来の不死化細胞
US7736892B2 (en) * 2002-02-25 2010-06-15 Kansas State University Research Foundation Cultures, products and methods using umbilical cord matrix cells
US20030161818A1 (en) * 2002-02-25 2003-08-28 Kansas State University Research Foundation Cultures, products and methods using stem cells
US20050250202A1 (en) 2002-03-19 2005-11-10 March Keith L Adipose stromal stem cells for tissue and vascular modification
KR20040094910A (ko) * 2002-04-03 2004-11-10 아르테셀 사이언스, 인크. 개선된 지방세포 분화된 지방 유래 성체 줄기세포 및 이의용도
AU2003259152A1 (en) * 2002-07-23 2004-02-09 Boston Scientific Limited Cell therapy for regeneration
AR047712A1 (es) 2002-09-07 2006-02-15 Royal Veterinary College Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas
US7767098B2 (en) * 2002-10-03 2010-08-03 Vida Tavafoghi Vida Method for harvesting fat cells from a fat-fluid mixture
US20040259948A1 (en) * 2003-01-10 2004-12-23 Peter Tontonoz Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
US20040151706A1 (en) * 2003-01-27 2004-08-05 Alex Shakhov Collection and storage of biological specimens containing stem cells from healthy individuals for future use in treatment of their own cytopathological illnesses or other medical conditions
WO2004072273A1 (en) 2003-02-11 2004-08-26 Davies John E Progenitor cells from wharton's jelly of human umbilical cord
MXPA05009044A (es) 2003-02-20 2006-03-17 Macropore Biosurgery Inc Metodos para utilizar celulas derivadas de tejido adiposo en el tratamiento de condiciones cardiovasculares.
JP2007508018A (ja) 2003-10-08 2007-04-05 べト−ステム インコーポレイテッド 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット
US20100317671A1 (en) 2008-07-21 2010-12-16 Kaohsiung Medical University Xanthine-based cyclic gmp-enhancing rho-kinase inhibitor inhibits physiological activities of lung epithelial cell line
AU2009201915C1 (en) 2008-08-22 2015-02-26 Regeneus Ltd Therapeutic methods
PT2611906T (pt) 2010-08-31 2024-04-16 Gallant Pet Inc Terapias sistémicas com células estaminais alogénicas para tratamento de doenças em gatos e cães
IN2013MU02047A (es) 2013-06-17 2015-06-05 Kasiak Res Pvt Ltd
US20150044166A1 (en) 2013-08-08 2015-02-12 Riddle Institute Compositions and methods for treatment of exercise-induced pulmonary hemorrhage or nasopharyngeal cicatrix
US20150147409A1 (en) 2013-11-22 2015-05-28 Indiana University Research And Technology Corporation Adipose stromal vascular fraction-conditioned medium
US20180353549A1 (en) 2015-12-04 2018-12-13 Vet-Stem, Inc. Compositions and method for treating and preventing bleeding and lung injuries and diseases

Also Published As

Publication number Publication date
WO2005035742A2 (en) 2005-04-21
JP2007508018A (ja) 2007-04-05
EP2450433A3 (en) 2012-08-08
US20170196912A1 (en) 2017-07-13
CA2542120C (en) 2018-07-10
US20220184139A1 (en) 2022-06-16
WO2005035742A3 (en) 2005-09-09
EP1678295A2 (en) 2006-07-12
US11129855B2 (en) 2021-09-28
CA2542120A1 (en) 2005-04-21
EP2450433A2 (en) 2012-05-09
EP1678295B1 (en) 2013-03-06
SG146691A1 (en) 2008-10-30
US20200306317A1 (en) 2020-10-01
US20190255120A1 (en) 2019-08-22
US20070274960A1 (en) 2007-11-29
US9453202B2 (en) 2016-09-27
US10668105B2 (en) 2020-06-02
AU2004280616A1 (en) 2005-04-21
NZ597965A (en) 2013-09-27
JP2012080882A (ja) 2012-04-26

Similar Documents

Publication Publication Date Title
CR8380A (es) Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos
AR049985A1 (es) Tratamiento de combinacion para enfermedades malignas no hematologicas
HUS1700012I1 (hu) Bruton-tirozinkináz inhibitorok
UY29284A1 (es) Anticuerpos ab(beta) humanizados usados en mejorar la cognicion
CL2011003346A1 (es) Compuestos derivados de 2,3-dihidro-5h-[1,3]tiazolo[3,2-a]pirimidin-5-ona, moduladores de pi3k; composicion farmaceutica; y uso para tratar una enfermedad de base inmunologica, cancer o enfermedad pulmonar en un paciente.
DK1970059T3 (da) Lægemiddel med calciumdobesilat til behandling og profylakse af senelidelser
AR060306A1 (es) Terapia de combinacion de anticuerpos contra ctla4
NO20074999L (no) Metode og preparat for behandling av perifere vaskulaere sykdommer
NO20065227L (no) Menoklonale antistoff mot hepatocytt vekstfaktor
HUS1500058I1 (hu) Benzoxazint tartalmazó gyógyszer-kombináció légúti betegségek kezelésére
EA201001695A1 (ru) Применение эпотилона d для лечения заболеваний, связанных с тау-белком
AR034213A1 (es) Composiciones de medicamentos sobre la base de agentes anticolinergicos e inhibidores de pde-iv
BRPI0510094A (pt) uso de flibanserina no tratamento pré-menstrual e outros distúrbios sexuais femininos
MX2009006327A (es) Compuestos heterociclicos y metodos de uso de los mismos.
IL189104A (en) Pharmaceutical preparation containing lasalazide or sodium balasalazide for use in the treatment of gastrointestinal disorders.
CY1115407T1 (el) Θοριο-227 για χρηση στην ακτινοθεραπεια ασθενειων των μαλακων ιστων
EP1543158A4 (en) REGULATED APTAMER THERAPEUTICS
GT200500127A (es) Composiciones y metodos para el tratamiento de trastorno disforico premenstrual
GB0416508D0 (en) Therapeutic agents
BR0313413A (pt) Uso da vacinação beta amilóide juntamente com um inibidor da cox-2 seletivo para o tratamento da doença de alzheimer
ATE353650T1 (de) Kombinationstherapie zur behandlung von krebs
CY1109666T1 (el) Μεθοδος θεραπειας διαταραχων ξηροφθαλμιας και ραγοειδιτιδας
DK1596879T3 (da) Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis
BR0317772A (pt) Método de tratamento de um distúrbio de comportamento, uso de um composto, e, agente terapêutico para um distúrbio de comportamento
UA6522U (en) Method for treating patients with multiple and combined injuries of long bones

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)