CR9204A - Compuestos de piridazinona - Google Patents

Compuestos de piridazinona

Info

Publication number
CR9204A
CR9204A CR9204A CR9204A CR9204A CR 9204 A CR9204 A CR 9204A CR 9204 A CR9204 A CR 9204A CR 9204 A CR9204 A CR 9204A CR 9204 A CR9204 A CR 9204A
Authority
CR
Costa Rica
Prior art keywords
compounds
piridazinona
pyridarizinone
hepatitis
virus
Prior art date
Application number
CR9204A
Other languages
English (en)
Inventor
Zhou Yuefen
Li Liansheng
E Webber Stephen
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Publication of CR9204A publication Critical patent/CR9204A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invencion esta dirigida a compuestos de piridarizinona y a composiciones farmaceuticas que contienen estos compuestos que sonutiles en el tratamiento del virus de hepatitis C.
CR9204A 2004-12-17 2007-06-22 Compuestos de piridazinona CR9204A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63661604P 2004-12-17 2004-12-17

Publications (1)

Publication Number Publication Date
CR9204A true CR9204A (es) 2007-09-06

Family

ID=36588590

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9204A CR9204A (es) 2004-12-17 2007-06-22 Compuestos de piridazinona

Country Status (21)

Country Link
US (1) US7425552B2 (es)
EP (1) EP1824847A2 (es)
JP (1) JP2008526687A (es)
KR (1) KR20070100743A (es)
CN (1) CN101137651A (es)
AP (1) AP2007004040A0 (es)
AR (1) AR054214A1 (es)
AU (1) AU2005316396A1 (es)
CA (1) CA2589527A1 (es)
CR (1) CR9204A (es)
EA (1) EA200701297A1 (es)
GT (1) GT200500373A (es)
IL (1) IL183510A0 (es)
MX (1) MX2007007264A (es)
NO (1) NO20073105L (es)
PA (1) PA8657001A1 (es)
PE (1) PE20060871A1 (es)
SV (1) SV2006002347A (es)
TW (1) TW200635596A (es)
UY (1) UY29266A1 (es)
WO (1) WO2006066079A2 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006066079A2 (en) 2004-12-17 2006-06-22 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
ES2600460T3 (es) 2005-05-10 2017-02-09 Intermune, Inc. Derivados de piridona-2-ona como moduladores del sistema de proteína cinasa activada por estrés
WO2008051637A2 (en) * 2006-06-22 2008-05-02 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
NZ573875A (en) 2006-06-22 2011-11-25 Anadys Pharmaceuticals Inc Pyrro[1,2-b]pyridazinone compounds
TW200840572A (en) 2006-12-12 2008-10-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
WO2008073987A1 (en) * 2006-12-12 2008-06-19 Anadys Pharmaceuticals, Inc. Saturated fused [1,2-b] pyridazinone compounds
US20080188466A1 (en) * 2006-12-21 2008-08-07 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
US20080275032A1 (en) * 2006-12-29 2008-11-06 Yuefen Zhou Pyridazinone compounds
US20080227774A1 (en) * 2007-03-15 2008-09-18 Frank Ruebsam 5,5-disubstituted-indolizinone compounds
UA100120C2 (en) 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
EP2142215B1 (en) 2007-05-04 2012-03-07 Vertex Pharmceuticals Incorporated Combination therapy for the treatment of hcv infection
US20080292588A1 (en) * 2007-05-17 2008-11-27 Anadys Pharmaceuticals, Inc. 1-methyl-benzo[1,2,4]thiadiazine 1-oxide derivatives
ITMI20071012A1 (it) * 2007-05-18 2008-11-19 St Microelectronics Srl Dispositivo di memoria migliorato a veloce programmazione
US7834009B2 (en) * 2007-08-27 2010-11-16 Anadys Pharmaceuticals, Inc. 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds
CN102099036B (zh) 2008-06-03 2015-05-27 英特芒尼公司 用于治疗炎性疾患和纤维化疾患的化合物和方法
WO2009152166A1 (en) * 2008-06-10 2009-12-17 Anadys Pharmaceuticals, Inc. [1,2,4]thiadiazine 1,1-dioxide compounds
US20110229438A1 (en) * 2008-10-09 2011-09-22 Anadys Pharmaceuticals, Inc. Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
TW201026675A (en) * 2008-10-09 2010-07-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
WO2010082050A1 (en) 2009-01-16 2010-07-22 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
WO2011045271A1 (de) 2009-10-15 2011-04-21 Bayer Cropscience Ag Herbizid wirksame heterocyclylsubstituierte pyridazinone
CN102858344A (zh) * 2009-10-28 2013-01-02 安那迪斯药品股份有限公司 氘化5,6-二氢-1h-吡啶-2-酮化合物
PH12012501216A1 (en) 2009-12-18 2012-11-05 Boehringer Ingelheim Int Hcv combination therapy
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
WO2014121416A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
WO2014121417A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
WO2014121418A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
MX382781B (es) 2014-04-02 2025-03-13 Intermune Inc Piridinonas anti-fibroticas.
US10118917B2 (en) * 2014-04-29 2018-11-06 E I Du Pont De Nemours And Company Pyridazinone herbicides
KR102624961B1 (ko) 2015-12-07 2024-01-16 디아이씨 가부시끼가이샤 중합성 화합물의 제조 방법
CN105999097A (zh) * 2016-07-08 2016-10-12 王恩禄 一种治疗乙肝的中药组合物
US20220233542A1 (en) * 2019-06-05 2022-07-28 University Of Georgia Research Foundation Compositions and methods for preventing or treating human immunodeficiency virus associated pulmonary arterial hypertension

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
WO2001085172A1 (en) 2000-05-10 2001-11-15 Smithkline Beecham Corporation Novel anti-infectives
US20060003346A1 (en) 2000-08-11 2006-01-05 Ashok Amin Method for treating hepatitis
AR036081A1 (es) 2001-06-07 2004-08-11 Smithkline Beecham Corp Compuesto de 1,2-dihidroquinolina, su uso para preparar una composicion farmaceutica, metodos para prepararlo y compuestos del acido 2-aminobenzoico n-alquilado de utilidad como intermediarios en dichos metodos
WO2003059356A2 (en) 2001-10-30 2003-07-24 Smithkline Beecham Corporation Novel anti-infectives
US7601709B2 (en) 2003-02-07 2009-10-13 Enanta Pharmaceuticals, Inc. Macrocyclic hepatitis C serine protease inhibitors
US7439246B2 (en) 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
CA2577528A1 (en) 2004-08-23 2006-03-02 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
WO2006066079A2 (en) 2004-12-17 2006-06-22 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
BRPI0607533A2 (pt) 2005-04-21 2009-09-15 Nippon Shinyaku Co Ltd derivado de ftalazinona, composição farmacêutica, inibidor de fosfodiesterase do tipo 4,supressor da produção de tnf-alfa, agente preventivo ou terapêutico, preparado externo, bem como uso do referido derivado
JP2008540370A (ja) * 2005-05-04 2008-11-20 エフ.ホフマン−ラ ロシュ アーゲー ヘテロ環式抗ウイルス化合物
NZ573875A (en) 2006-06-22 2011-11-25 Anadys Pharmaceuticals Inc Pyrro[1,2-b]pyridazinone compounds

Also Published As

Publication number Publication date
PE20060871A1 (es) 2006-09-04
TW200635596A (en) 2006-10-16
US20060189602A1 (en) 2006-08-24
US7425552B2 (en) 2008-09-16
IL183510A0 (en) 2007-09-20
UY29266A1 (es) 2006-07-31
CN101137651A (zh) 2008-03-05
KR20070100743A (ko) 2007-10-11
NO20073105L (no) 2007-09-13
WO2006066079A2 (en) 2006-06-22
CA2589527A1 (en) 2006-06-22
AU2005316396A1 (en) 2006-06-22
WO2006066079A3 (en) 2006-12-14
EP1824847A2 (en) 2007-08-29
SV2006002347A (es) 2006-08-25
PA8657001A1 (es) 2006-08-03
GT200500373A (es) 2006-10-02
EA200701297A1 (ru) 2007-12-28
AP2007004040A0 (en) 2007-06-30
JP2008526687A (ja) 2008-07-24
AR054214A1 (es) 2007-06-13
MX2007007264A (es) 2007-08-14

Similar Documents

Publication Publication Date Title
CR9204A (es) Compuestos de piridazinona
HN2008000087A (es) Inhibidores de la proteasa ns3 del vhc
ECSP045429A (es) Combinacion de compuestos organicos
PA8733401A1 (es) Compuestos de pirro[1,2-b]piridazinona
EA200970916A1 (ru) Соединения 5,6-дигидро-1н-пиридин-2-она
HN2009000792A (es) Inhibidores de la proteasa ns3 del hcv
EA201070544A1 (ru) Новый класс терапевтических веществ, усиливающих диффузию низкомолекулярных соединений
CR8410A (es) Quinolinas utiles en el tratamiento de enfermedades cardiovasculares
CL2008001855A1 (es) Compuestos ciclicos condensados derivados del boro; composicion farmaceutica; y uso en el tratamiento y/o prevencion de una enfermedad infecciosa.
UY30778A1 (es) Compuestos de 5,6-dihidro-1h-piridin-2-ona
CR8888A (es) Indazoles utiles en el tratamiento de enfermedades cardiovasculares
CL2011001224A1 (es) Compuestos derivados de benzofurano-3-carboxamida; composicion farmaceutica que los comprende; y su uso en tratamiento del virus de la hepatitis c.
UY35542A (es) Métodos y composiciones para tratar el virus de la hepatitis c
MXPA05010782A (es) Nuevos hidroxamatos como agentees terapeuticos.
CR11316A (es) Derivado de uracilo o timina para el tratamiiento de la hepatitis c.
CR7235A (es) Inhibidores beta- amino tetrahidroimidazol (1,2-a) pirazinas y tetrahidrotrioazolo (4,3-a) pirazinas como depetidil peptidasa para el tratamiento o prevencion de la diabetes
ECSP088208A (es) Nuevos inhibidores macrocíclicos de la replicación del virus de hepatitis c
CR8824A (es) Derivados de 2-carbamida-4-feniltiazol, su preparacion y su aplicacion en terapeutica
UY29112A1 (es) Derivados de pirazol condensado, su preparacion y su aplicacion terapeutica
GT200900082A (es) Composiciones de fenilalquilamino-carbamato
ECSP067120A (es) 3-aminociclopentanocarboxamidas como moduladores de receptores de quimioquinas
EA201170605A1 (ru) Циклоундекадепсипептидные соединения и применение указанных соединений в качестве лекарственного средства
UY30675A1 (es) Metodos para el tratamiento de la depresion
EA200801220A1 (ru) 3-аминоциклопентанекарбоксамиды в качестве модуляторов хемокиновых рецепторов
MX2011006516A (es) Terapia de combinacion de virus de hepatitis c.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)