CR9432A - Derivado de bencimidazol y uso como antagonista de angiotensina ii - Google Patents

Derivado de bencimidazol y uso como antagonista de angiotensina ii

Info

Publication number
CR9432A
CR9432A CR9432A CR9432A CR9432A CR 9432 A CR9432 A CR 9432A CR 9432 A CR9432 A CR 9432A CR 9432 A CR9432 A CR 9432A CR 9432 A CR9432 A CR 9432A
Authority
CR
Costa Rica
Prior art keywords
angonotensin
bencimidazol
antagonist
derived
methyl
Prior art date
Application number
CR9432A
Other languages
English (en)
Inventor
Kuroita Takanobu
Ojima Mami
Ban Junko
Original Assignee
Takeda Pharmaceuticla Company Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticla Company Ltd filed Critical Takeda Pharmaceuticla Company Ltd
Publication of CR9432A publication Critical patent/CR9432A/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

La presente invencion proporciona (2-ciclopropil- l- (2-(5-oxo-4,5.dihidro-1,2,4-oxadiazol-3-il) bifenil-4-il) metil) 1h bencimidazol-7-carboxilato de 5-metil-2-oxo-1,3-dioxol-4- il) metilo representado por formula (i), que presenta propiedades superiores como un agente Farmaceutico, una de sus sales, uno de sus cristales, un agente farmaceutico que contiene el compuesto y otros
CR9432A 2005-03-30 2007-10-11 Derivado de bencimidazol y uso como antagonista de angiotensina ii CR9432A (es)

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JP2005099788 2005-03-30
JP2005198014 2005-07-06

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AU (1) AU2006231418B2 (es)
BR (1) BRPI0608944A2 (es)
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CA2642988C (en) * 2006-02-27 2015-10-27 Takeda Pharmaceutical Company Limited Pharmaceutical product comprising a benzimidazole in combination with a desiccant
WO2007097452A1 (ja) * 2006-02-27 2007-08-30 Takeda Pharmaceutical Company Limited 医薬用ブリスターパッケージ
ATE552818T1 (de) * 2006-09-25 2012-04-15 Takeda Pharmaceutical Medizinische verpackung
EP1988091B1 (en) * 2007-02-07 2015-06-10 Kyowa Hakko Kirin Co., Ltd. Tricyclic compounds
JP5635491B2 (ja) 2008-07-31 2014-12-03 武田薬品工業株式会社 固形医薬組成物
JP5559689B2 (ja) 2008-08-06 2014-07-23 協和発酵キリン株式会社 ３環系化合物
TW201014850A (en) 2008-09-25 2010-04-16 Takeda Pharmaceutical Solid pharmaceutical composition
JP2014505097A (ja) * 2011-02-08 2014-02-27 ジュビラント ライフ サイエンセズ リミテッド アジルサルタンメドキソミルの改良製造方法
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102827153B (zh) * 2011-06-14 2016-10-05 江苏豪森药业集团有限公司 阿齐沙坦的晶型及其制备方法
JP6281735B2 (ja) * 2013-03-19 2018-02-21 トーアエイヨー株式会社 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法

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PT1863801E (pt) 2010-11-19
HRP20080552A9 (en) 2009-08-31
MY146254A (en) 2012-07-31
EP1863801B1 (en) 2010-09-29
JP4795362B2 (ja) 2011-10-19
RS20080510A (sr) 2009-07-15
MA29438B1 (fr) 2008-05-02
AU2006231418B2 (en) 2011-10-13
EP1863801A2 (en) 2007-12-12
RU2407742C2 (ru) 2010-12-27
AR055755A1 (es) 2007-09-05
CY1111168T1 (el) 2015-06-11
NO20075399L (no) 2007-12-19
PE20061195A1 (es) 2006-12-21
SI1863801T1 (sl) 2010-12-31
AU2006231418A1 (en) 2006-10-12
HRP20080552A2 (hr) 2009-03-31
JP2011190265A (ja) 2011-09-29
PL1863801T3 (pl) 2011-03-31
JP2008534434A (ja) 2008-08-28
CA2602624A1 (en) 2006-10-12
US20120172401A1 (en) 2012-07-05
RU2007139928A (ru) 2009-05-10
KR20070116648A (ko) 2007-12-10
WO2006107062A2 (en) 2006-10-12
WO2006107062A3 (en) 2006-12-14
BRPI0608944A2 (pt) 2010-11-16
US20090054502A1 (en) 2009-02-26
DE602006017183D1 (de) 2010-11-11
DK1863801T3 (da) 2010-11-15
NZ562887A (en) 2010-10-29
IL185726A0 (en) 2008-01-06
HK1115584A1 (en) 2008-12-05
TW200724539A (en) 2007-07-01
GEP20115138B (en) 2011-01-10
MEP33308A (en) 2010-10-10
IL185726A (en) 2012-07-31

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