CR9766A - METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS - Google Patents
METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERSInfo
- Publication number
- CR9766A CR9766A CR9766A CR9766A CR9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A
- Authority
- CR
- Costa Rica
- Prior art keywords
- substance
- phenyl
- alkyl
- group
- treatment
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000011117 substance-related disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Esta invencion esta dirigida a un metodo para prevenir, tratar o aliviar trastornos relacionados con sustancias, en un sujeto que necesita el mismo que comprende administrar al sujeto una cantidad efectiva de un compuesto seleccionado de la formula (I) o la formula (II): o formas farmaceuticamente aceptables del mismo, en donde el fenilo es sustituido en X con uno a cinco atomos de halogeno seleccionados del grupo que consiste de fluor, cloro, bromo y yodo, y R1, R2, R3, R4, R5, y R6 se seleccionan independientemente del grupo que consiste de hidrogeno y alquilo de C1-4 en donde alquilo de c1-4 es opcionalmente sustituido con fenilo (y, en donde el fenilo es opcionalmente sustituido con sustituyentes independientemente seleccionados del grupo que consiste de halogeno, alquilo de c1-4, alcoxi de C1-C4, amino, nitro y ciano); ademas, se incluyen metodos que implican la co-administracion de compuestos de la invencion con uno o mas compuestos conocidos para el tratamiento de trastornos inducidos por sustancias.This invention is directed to a method for preventing, treating or alleviating substance-related disorders, in a subject that needs the same which comprises administering to the subject an effective amount of a compound selected from the formula (I) or the formula (II): or pharmaceutically acceptable forms thereof, wherein the phenyl is substituted in X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine, and R1, R2, R3, R4, R5, and R6 are independently selected from the group consisting of hydrogen and C1-4 alkyl wherein C1-4 alkyl is optionally substituted with phenyl (and, wherein the phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1 alkyl -4, C1-C4 alkoxy, amino, nitro and cyano); In addition, methods involving the co-administration of compounds of the invention with one or more known compounds for the treatment of substance-induced disorders are included.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CR9766A CR9766A (en) | 2008-02-26 | 2008-02-26 | METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CR9766A CR9766A (en) | 2008-02-26 | 2008-02-26 | METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR9766A true CR9766A (en) | 2008-09-09 |
Family
ID=44839415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR9766A CR9766A (en) | 2008-02-26 | 2008-02-26 | METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS |
Country Status (1)
| Country | Link |
|---|---|
| CR (1) | CR9766A (en) |
-
2008
- 2008-02-26 CR CR9766A patent/CR9766A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |