CR9989A - Composición farmacéutica que comprende al menos un medicamento contra el cáncer y al menos un polímero - Google Patents
Composición farmacéutica que comprende al menos un medicamento contra el cáncer y al menos un polímeroInfo
- Publication number
- CR9989A CR9989A CR9989A CR9989A CR9989A CR 9989 A CR9989 A CR 9989A CR 9989 A CR9989 A CR 9989A CR 9989 A CR9989 A CR 9989A CR 9989 A CR9989 A CR 9989A
- Authority
- CR
- Costa Rica
- Prior art keywords
- medicinal
- polymer
- pharmaceutical composition
- methods
- against cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 208000022605 chemotherapy-induced alopecia Diseases 0.000 abstract 1
- 229960003668 docetaxel Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a composiciones mejoradas de drogas contra el cáncer, preferiblemente taxanos, tal como paclitaxel y docetaxel, sus derivados o sus análogos, métodos de fabricación de estas composiciones y métodos de fraccionamiento de las partículas en rango de tamaño particular y métodos para tratar pacientes con cáncer con estas composiciones, que proveen una reducción de los efectos secundarios inducidos por la quimioterapia especialmente una reducción de la alopecia inducida por la quimioterapia. La composición es tal que sustancialmente no hay droga libre en dicha composición.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1327MU2005 | 2005-10-21 | ||
| IN1081MU2006 | 2006-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR9989A true CR9989A (es) | 2008-07-18 |
Family
ID=38163340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR9989A CR9989A (es) | 2005-10-21 | 2008-05-20 | Composición farmacéutica que comprende al menos un medicamento contra el cáncer y al menos un polímero |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100166872A1 (es) |
| EP (1) | EP1962906A4 (es) |
| JP (1) | JP2009512682A (es) |
| AR (1) | AR058130A1 (es) |
| AU (1) | AU2006324872B2 (es) |
| BR (1) | BRPI0617663A2 (es) |
| CA (1) | CA2626016A1 (es) |
| CR (1) | CR9989A (es) |
| EA (1) | EA015781B1 (es) |
| IL (1) | IL190882A0 (es) |
| MA (1) | MA29946B1 (es) |
| RS (1) | RS20080167A (es) |
| WO (1) | WO2007069272A2 (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009087678A2 (en) * | 2007-12-24 | 2009-07-16 | Sun Pharma Advanced Research Company Limited | Nanodispersion |
| US8865223B2 (en) | 2008-02-11 | 2014-10-21 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents |
| US8871276B2 (en) | 2008-02-11 | 2014-10-28 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents |
| WO2009101614A1 (en) * | 2008-02-11 | 2009-08-20 | Technion Research & Development Foundation Ltd. | Casein particles encapsulating therapeutically active agents and uses thereof |
| US8865222B2 (en) | 2008-02-11 | 2014-10-21 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for enrichment of food and beverages and methods of preparation thereof |
| GB0818747D0 (en) | 2008-10-13 | 2008-11-19 | Univ Nottingham | Biocompatible responsive materials |
| EP2266546A1 (en) | 2009-06-08 | 2010-12-29 | Advancell Advanced in Vitro Cell Technologies,S.A. | Process for the preparation of colloidal systems for the delivery of active compounds |
| EP2442805A4 (en) | 2009-06-19 | 2012-11-21 | Sun Pharma Advanced Res Co Ltd | NANODISPERSION OF A MEDICINE AND METHOD FOR PREPARING THE SAME |
| WO2011017835A1 (en) * | 2009-08-11 | 2011-02-17 | Nanjing University | Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding |
| IN2012DN02576A (es) * | 2009-09-21 | 2015-08-28 | Jw Pharmaceutical Corportion | |
| US10842770B2 (en) | 2010-05-03 | 2020-11-24 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| CA2801309C (en) * | 2010-06-01 | 2018-07-17 | Geistlich Pharma Ag | Methods and compositions for oral pharmaceutical therapy |
| WO2012058462A2 (en) * | 2010-10-29 | 2012-05-03 | Isis Pharmaceuticals, Inc. | Combination therapy for the treatment of cancer |
| EP2645991B1 (en) | 2010-12-02 | 2020-02-12 | GreenMark Biomedical Inc. | Aptamer bioconjugate drug delivery device |
| KR20140022904A (ko) | 2011-04-20 | 2014-02-25 | 유니버시티 오브 시드니 | 치료방법 및 그에 사용가능한 제제 |
| DK2701684T3 (en) | 2011-04-28 | 2017-09-18 | Platform Brightworks Two Ltd | Improved parenteral formulations of lipophilic pharmaceuticals and methods for their preparation and use |
| WO2013124867A1 (en) * | 2012-02-21 | 2013-08-29 | Amrita Vishwa Vidyapeetham University | Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules |
| JP6280546B2 (ja) | 2012-06-26 | 2018-02-14 | デル マー ファーマシューティカルズ | ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| US10143700B2 (en) | 2013-02-19 | 2018-12-04 | Amrita Vishwa Vidyapeetham | Nanoparticle formulations for delivering multiple therapeutic agents |
| KR20160061911A (ko) | 2013-04-08 | 2016-06-01 | 데니스 엠. 브라운 | 최적하 투여된 화학 화합물의 치료 효과 |
| RS60093B1 (sr) | 2013-09-16 | 2020-05-29 | Astrazeneca Ab | Terapeutske polimerne nanočestice i postupci njihove pripreme i primene |
| KR20150047336A (ko) | 2013-10-24 | 2015-05-04 | 삼성전자주식회사 | 나노입자, 이를 제조하는 방법, 및 이의 용도 |
| HUP1300646A2 (en) | 2013-11-12 | 2015-05-28 | Druggability Technologies Ip Holdco Jersey Ltd | Complexes of fulvestrant and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
| CN103739672B (zh) * | 2013-12-31 | 2015-06-10 | 威特曼生物科技(南京)有限公司 | 一种聚乙二醇修饰的抑制vegfr2酪氨酸激酶多肽及其应用 |
| RU2591819C2 (ru) * | 2014-03-03 | 2016-07-20 | Закрытое акционерное общество "СКАЙ ЛТД" | Способ получения фолликулярного белкового препарата и препарат, полученный данным способом |
| CN117899029A (zh) | 2015-02-01 | 2024-04-19 | 希洛斯医药品股份有限公司 | 用于在患者中口服施用的含有砷的高表面积冻干组合物 |
| EP3265063A4 (en) | 2015-03-03 | 2018-11-07 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
| US9895313B2 (en) | 2015-03-03 | 2018-02-20 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
| CN106137969B (zh) | 2015-04-03 | 2020-05-15 | 四川科伦药物研究院有限公司 | 多西他赛白蛋白纳米粒药物组合物及其制备方法及应用 |
| IL285928B2 (en) | 2016-05-06 | 2025-06-01 | Eagle Pharmaceuticals Inc | Fulvestrant formulations and methods of their use |
| EP3615011A4 (en) * | 2017-04-24 | 2021-01-06 | ZY Therapeutics Inc. | PHARMACEUTICAL COMPOSITION FOR IN VIVO ADMINISTRATION, PROCESS FOR THE PREPARATION OF A PHARMACOLOGICALLY ACTIVE PRINCIPLE SENSITIVELY INSOLUBLE IN WATER |
| WO2019028457A2 (en) * | 2017-08-04 | 2019-02-07 | University Of Houston System | FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE |
| WO2019191456A1 (en) | 2018-03-28 | 2019-10-03 | Greenmark Biomedical Inc. | Phosphate crosslinked starch nanoparticle and dental treatments |
| AU2019312592B2 (en) | 2018-07-31 | 2025-06-26 | Microbion Corporation | Bismuth-thiol compositions and methods for treating wounds |
| WO2020028558A1 (en) | 2018-07-31 | 2020-02-06 | Microbion Corporation | Bismuth-thiol compositions and methods of use |
| FR3087650B1 (fr) * | 2018-10-31 | 2021-01-29 | Bio Even | Flavine adenine dinucleotide (fad) pour son utilisation pour la prevention et/ou le traitement de cancer |
| CN114767879A (zh) * | 2022-06-02 | 2022-07-22 | 平顶山学院 | 一种多西紫杉醇恶性肿瘤靶向微球及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2634397B2 (fr) * | 1986-12-31 | 1991-04-19 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules |
| US5766635A (en) * | 1991-06-28 | 1998-06-16 | Rhone-Poulenc Rorer S.A. | Process for preparing nanoparticles |
| WO1994026254A1 (en) * | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
| PT1023050E (pt) * | 1997-06-27 | 2013-12-04 | Abraxis Bioscience Llc | Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização |
| HK1045646A1 (zh) * | 1999-05-21 | 2002-12-06 | Abraxis Bioscience, Llc | 蛋白質穩定化的藥理學活性劑,其製備方法及其使用方法 |
| AU2458501A (en) * | 2000-01-05 | 2001-07-16 | Imarx Therapeutics, Inc. | Pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
| ITMI20001107A1 (it) * | 2000-05-18 | 2001-11-18 | Acs Dobfar Spa | Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel |
| EP1585504A4 (en) * | 2002-11-06 | 2009-07-15 | Azaya Therapeutics Inc | Protein stabilized liposomal formulations of pharmaceutical active ingredients |
| KR20120068035A (ko) * | 2002-12-09 | 2012-06-26 | 아브락시스 바이오사이언스, 엘엘씨 | 약리학적 물질의 조성물 및 그 전달방법 |
-
2006
- 2006-10-19 BR BRPI0617663-1A patent/BRPI0617663A2/pt not_active IP Right Cessation
- 2006-10-19 AU AU2006324872A patent/AU2006324872B2/en not_active Expired - Fee Related
- 2006-10-19 WO PCT/IN2006/000427 patent/WO2007069272A2/en not_active Ceased
- 2006-10-19 US US12/083,594 patent/US20100166872A1/en not_active Abandoned
- 2006-10-19 RS RSP-2008/0167A patent/RS20080167A/sr unknown
- 2006-10-19 EA EA200801132A patent/EA015781B1/ru not_active IP Right Cessation
- 2006-10-19 JP JP2008536207A patent/JP2009512682A/ja active Pending
- 2006-10-19 EP EP06847315A patent/EP1962906A4/en not_active Withdrawn
- 2006-10-19 CA CA002626016A patent/CA2626016A1/en not_active Abandoned
- 2006-10-20 AR ARP060104602A patent/AR058130A1/es unknown
-
2008
- 2008-04-15 IL IL190882A patent/IL190882A0/en unknown
- 2008-05-15 MA MA30925A patent/MA29946B1/fr unknown
- 2008-05-20 CR CR9989A patent/CR9989A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS20080167A (sr) | 2009-07-15 |
| JP2009512682A (ja) | 2009-03-26 |
| CA2626016A1 (en) | 2007-06-21 |
| AU2006324872B2 (en) | 2012-03-08 |
| BRPI0617663A2 (pt) | 2011-08-02 |
| EA015781B1 (ru) | 2011-12-30 |
| EP1962906A4 (en) | 2009-11-18 |
| AR058130A1 (es) | 2008-01-23 |
| MA29946B1 (fr) | 2008-11-03 |
| WO2007069272A2 (en) | 2007-06-21 |
| US20100166872A1 (en) | 2010-07-01 |
| EA200801132A1 (ru) | 2009-02-27 |
| WO2007069272A3 (en) | 2007-08-23 |
| AU2006324872A1 (en) | 2007-06-21 |
| EP1962906A2 (en) | 2008-09-03 |
| IL190882A0 (en) | 2008-11-03 |
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