CS121391A3 - Protein-containing pharmaceutical - Google Patents

Protein-containing pharmaceutical

Info

Publication number
CS121391A3
CS121391A3 CS911213A CS121391A CS121391A3 CS 121391 A3 CS121391 A3 CS 121391A3 CS 911213 A CS911213 A CS 911213A CS 121391 A CS121391 A CS 121391A CS 121391 A3 CS121391 A3 CS 121391A3
Authority
CS
Czechoslovakia
Prior art keywords
protein
containing pharmaceutical
compsn
prepare
new
Prior art date
Application number
CS911213A
Other languages
Czech (cs)
Inventor
Johann Eibl
Ludwig Pichler
Hans-Peter Schwarz
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of CS121391A3 publication Critical patent/CS121391A3/en
Publication of CZ280004B6 publication Critical patent/CZ280004B6/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The use of opt. activated protein C (I) to prepare a compsn. for normalising increased vascular permeabilty and to inhibit permeability defects of the vascular wall is new. Also new is the use of (I) to prepare a compsn. for stimulating the beta-adrenergic receptors.
CS911213A 1990-08-16 1991-04-26 The use of c protein or activated c protein for the preparation of pharmaceutical preparations CZ280004B6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0169790A AT402260B (en) 1990-08-16 1990-08-16 PROTEIN C-CONTAINING PHARMACEUTICAL PREPARATION
EP91890012A EP0471660B1 (en) 1990-08-16 1991-01-28 Protein C for treating pain

Publications (2)

Publication Number Publication Date
CS121391A3 true CS121391A3 (en) 1992-02-19
CZ280004B6 CZ280004B6 (en) 1995-09-13

Family

ID=3519039

Country Status (12)

Country Link
EP (3) EP0533210B1 (en)
JP (1) JP2530770B2 (en)
AT (6) AT402260B (en)
CA (1) CA2041380C (en)
CZ (1) CZ280004B6 (en)
DE (3) DE59108697D1 (en)
DK (3) DK0471660T3 (en)
ES (3) ES2080289T3 (en)
HR (1) HRP921237A2 (en)
HU (1) HUT60147A (en)
RU (1) RU2066550C1 (en)
YU (1) YU77591A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571786A (en) * 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
AT397615B (en) * 1991-05-14 1994-05-25 Immuno Ag MEDICINAL PRODUCT PROTEIN C
DE4320294A1 (en) * 1993-06-18 1994-12-22 Immuno Ag Use of human protein C to prevent and treat platelet deposits
ES2179129T3 (en) * 1995-03-21 2003-01-16 Baxter Ag AGENT FOR THE SUBCUTANEOUS APPLICATION OF PROTEIN C.
DE19608218A1 (en) * 1995-03-21 1996-09-26 Immuno Ag Agent for subcutaneous administration of protein C.
WO2006072137A1 (en) * 2005-01-07 2006-07-13 Northern Sydney And Central Coast Area Health Service Treatment for autoimmune and inflammatory conditions
JP6273272B2 (en) 2012-07-04 2018-01-31 ジージー バイオテック エルエルシー Treatment of inflammatory skin disorders
JP2017513944A (en) 2014-04-16 2017-06-01 ジージー バイオテック エルエルシー Treatment of abnormal skin scarring
CA2946032C (en) 2014-04-16 2022-06-14 Zz Biotech Llc Use of apc analogue for wound healing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2739050B2 (en) * 1988-01-28 1998-04-08 ヘキスト薬品工業株式会社 Anticoagulant
US5093117A (en) * 1989-01-24 1992-03-03 Baxter International Inc. Compositions and method for the treatment or prophylaxis of sepsis or septic shock

Also Published As

Publication number Publication date
EP0471660B1 (en) 1995-08-23
DK0471660T3 (en) 1995-12-18
ATE126699T1 (en) 1995-09-15
RU2066550C1 (en) 1996-09-20
JP2530770B2 (en) 1996-09-04
YU77591A (en) 1995-10-24
AT403439B (en) 1998-02-25
EP0471660A3 (en) 1992-04-15
HU911348D0 (en) 1991-10-28
DK0533209T3 (en) 1997-09-22
CA2041380A1 (en) 1992-02-17
ATE150649T1 (en) 1997-04-15
EP0471660A2 (en) 1992-02-19
CZ280004B6 (en) 1995-09-13
DE59106292D1 (en) 1995-09-28
EP0533210B1 (en) 1997-05-02
AT402260B (en) 1997-03-25
DE59108638D1 (en) 1997-04-30
ATA169790A (en) 1996-08-15
ATA20492A (en) 1997-10-15
EP0533209A1 (en) 1993-03-24
EP0533209B1 (en) 1997-03-26
EP0533210A1 (en) 1993-03-24
CA2041380C (en) 1997-10-07
ATE152354T1 (en) 1997-05-15
ES2103861T3 (en) 1997-10-01
ES2102435T3 (en) 1997-08-01
ES2080289T3 (en) 1996-02-01
DE59108697D1 (en) 1997-06-05
HUT60147A (en) 1992-08-28
AT403763B (en) 1998-05-25
HRP921237A2 (en) 1995-10-31
JPH04230633A (en) 1992-08-19
DK0533210T3 (en) 1997-11-03
ATA20392A (en) 1997-07-15

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20040426