CS178889B2 - Method for preparation of oxazolopyridines and derivatives thereof - Google Patents

Method for preparation of oxazolopyridines and derivatives thereof

Info

Publication number: CS178889B2
Authority: CS; Czechoslovakia
Prior art keywords: oxazolopyridines; derivatives; preparation
Prior art date: 1972-06-14

Application number

CS7300004243A

Other languages

Czech (cs)

Inventor

Tsung-Ying Shen

Robert L Clark

Arsenio A Pessolano

Bruce E Witzel

Thomas J Lanza

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-14

Filing date

1973-06-12

Publication date

1977-10-31

1973-06-12 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1977-10-31 Publication of CS178889B2 publication Critical patent/CS178889B2/en

Links

BFPLMTPHDFFMTG-UHFFFAOYSA-N [1,3]oxazolo[5,4-b]pyridine Chemical class C1=CN=C2OC=NC2=C1 BFPLMTPHDFFMTG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

CS7300004243A 1972-06-14 1973-06-12 Method for preparation of oxazolopyridines and derivatives thereof CS178889B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26289872A	1972-06-14	1972-06-14
BE147896A BE819177R (en)	1972-06-14	1974-08-26	OXAZOLO- AND THIAZOLOPYRIDINES

Publications (1)

Publication Number	Publication Date
CS178889B2 true CS178889B2 (en)	1977-10-31

Family

ID=25648082

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS7300004243A CS178889B2 (en)	1972-06-14	1973-06-12	Method for preparation of oxazolopyridines and derivatives thereof

Country Status (17)

Country	Link
JP (1)	JPS5943475B2 (en)
AR (1)	AR208500A1 (en)
AT (1)	AT333277B (en)
AU (1)	AU472528B2 (en)
BE (2)	BE800868A (en)
CA (1)	CA1019741A (en)
CS (1)	CS178889B2 (en)
DD (1)	DD105237A5 (en)
DE (1)	DE2330109A1 (en)
DK (1)	DK152050C (en)
FI (1)	FI57417C (en)
FR (1)	FR2187356B1 (en)
GB (1)	GB1421619A (en)
LU (1)	LU67786A1 (en)
NL (1)	NL184836C (en)
SE (2)	SE401675B (en)
ZA (1)	ZA733760B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2527321A1 (en) *	1975-06-19	1976-12-23	Merck & Co Inc	2-(Substd phenyl) oxazolo (4,5-b) pyridines - topical anti-inflammatories with very low systemic activity
JPS527992A (en) *	1975-07-04	1977-01-21	Merck & Co Inc	Oxazolo 455b* pyridines
NL187021C (en) *	1975-07-15	1991-05-01	Merck & Co Inc	PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH ANTI-INFLAMMATORY ACTION, AND A METHOD FOR PREPARING ANTI-INFLAMMATIC ACTIVITY 2-PHENYL-OXAZOLO-PID-BIDANE.
US4011326A (en) *	1975-07-29	1977-03-08	Merck & Co., Inc.	2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
US4753673A (en) *	1977-07-22	1988-06-28	The Dow Chemical Company	Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use
EP0107866B1 (en) *	1977-08-12	1988-03-30	Imperial Chemical Industries Plc	Trihalomethylpyridine compounds
JPS5461182A (en) *	1977-10-20	1979-05-17	Ishihara Sangyo Kaisha Ltd	2-phenoxy-5-trifluoromethylpyridine compounds
JPS5461183A (en) *	1977-10-21	1979-05-17	Ishihara Sangyo Kaisha Ltd	2-substituted-5-trifluoromethyl pyridine compounds
DE2967674D1 (en) *	1978-02-15	1988-03-10	Ici Plc	Herbicidal derivatives of 2-(4(2-pyridyloxy)phenoxy)propane, processes for preparing them, and herbicidal compositions containing them
JPS55130840U (en) *	1979-03-12	1980-09-16
JPS55124763A (en) *	1979-03-19	1980-09-26	Ishihara Sangyo Kaisha Ltd	5-trifluoromethyl-2-pyridone derivative
GB8333514D0 (en) *	1983-12-16	1984-01-25	Erba Farmitalia	Tetrahydrothiazolo(5 4-c)pyridine derivatives
FR2652085A1 (en) *	1989-09-20	1991-03-22	Science Organisation	NEW PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE DERIVATIVES
JP2001503443A (en) *	1996-11-11	2001-03-13	ビイクグルデンロンベルクヒエーミツシエフアブリークゲゼルシヤフトミツトベシユレンクテルハフツング	New imidazo- and oxazolopyridine
US6232320B1 (en)	1998-06-04	2001-05-15	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
AU4231299A (en) *	1998-06-04	1999-12-20	Abbott Laboratories	Cell adhesion-inhibiting antinflammatory compounds
HK1045306A1 (en) *	1999-06-03	2002-11-22	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
WO2002036580A2 (en) *	2000-10-31	2002-05-10	Lynn Bonham	Benzoxazole lpaat- beta inhibitors and uses thereof
US8088928B2 (en)	2005-08-04	2012-01-03	Sirtris Pharmaceuticals, Inc.	Sirtuin modulating compounds
US7855289B2 (en) *	2005-08-04	2010-12-21	Sirtris Pharmaceuticals, Inc.	Sirtuin modulating compounds
US7345178B2 (en) *	2005-08-04	2008-03-18	Sirtris Pharmaceuticals, Inc.	Sirtuin modulating compounds
US8093401B2 (en)	2005-08-04	2012-01-10	Sirtris Pharmaceuticals, Inc.	Sirtuin modulating compounds
TW200916472A (en)	2007-06-20	2009-04-16	Sirtris Pharmaceuticals Inc	Sirtuin modulating compounds
AU2009285584B2 (en) *	2008-08-29	2015-04-02	Treventis Corporation	Butyrylcholinesterase ligands as diagnostic tools and treatment for deseases of the nervous system
CN102388054B (en)	2008-12-19	2015-03-04	西特里斯药业公司	Thiazolopyridine sirtuin modulating compounds
AR078463A1 (en) *	2009-09-30	2011-11-09	Sumitomo Chemical Co	COMPOSITION AND METHOD TO CONTROL PESTS OF ARTROPODES
RU2013114352A (en)	2010-09-15	2014-10-20	Ф. Хоффманн-Ля Рош Аг	AZABENZENESIAZOLES, COMPOSITIONS AND METHODS OF APPLICATION
TW201234965A (en)	2010-12-24	2012-09-01	Sumitomo Chemical Co	Fused heterocyclic compound and use for pest control thereof
EP3160940A4 (en) *	2014-06-25	2018-05-02	Epizyme, Inc.	Substituted benzene and 6,5-fused bicyclic heteroaryl compounds
TR201815071T4 (en)	2014-12-02	2018-11-21	Bayer Cropscience Ag	Bicyclic compounds as pesticides.
US10399966B2 (en)	2016-01-21	2019-09-03	University Of Washington	Compounds for treatment of trypanosomes and neurological pathogens and uses thereof
KR102440762B1 (en) *	2016-07-07	2022-09-05	호도가야 가가쿠 고교 가부시키가이샤	A compound having a benzoazole ring structure and an organic electroluminescent device

1973
- 1973-03-12 AR AR248527A patent/AR208500A1/en active
- 1973-05-22 FI FI1657/73A patent/FI57417C/en active
- 1973-05-24 DK DK284973A patent/DK152050C/en not_active IP Right Cessation
- 1973-05-25 SE SE7307412A patent/SE401675B/en unknown
- 1973-05-30 NL NLAANVRAGE7307582,A patent/NL184836C/en not_active IP Right Cessation
- 1973-06-04 AU AU56511/73A patent/AU472528B2/en not_active Expired
- 1973-06-04 ZA ZA00733760A patent/ZA733760B/en unknown
- 1973-06-05 CA CA173,275A patent/CA1019741A/en not_active Expired
- 1973-06-08 AT AT508673A patent/AT333277B/en active
- 1973-06-11 GB GB2763273A patent/GB1421619A/en not_active Expired
- 1973-06-12 CS CS7300004243A patent/CS178889B2/en unknown
- 1973-06-12 DD DD171559A patent/DD105237A5/xx unknown
- 1973-06-13 DE DE2330109A patent/DE2330109A1/en not_active Withdrawn
- 1973-06-13 BE BE132231A patent/BE800868A/en not_active IP Right Cessation
- 1973-06-13 FR FR7321443A patent/FR2187356B1/fr not_active Expired
- 1973-06-13 LU LU67786A patent/LU67786A1/xx unknown
- 1973-06-14 JP JP48066453A patent/JPS5943475B2/en not_active Expired
1974
- 1974-08-26 BE BE147896A patent/BE819177R/en not_active IP Right Cessation
1976
- 1976-04-14 SE SE7604385A patent/SE432767B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AT333277B (en)	1976-11-10
GB1421619A (en)	1976-01-21
NL184836C (en)	1989-11-16
CA1019741A (en)	1977-10-25
SE7604385L (en)	1976-04-14
FI57417C (en)	1980-08-11
NL7307582A (en)	1973-12-18
SE432767B (en)	1984-04-16
DE2330109A1 (en)	1974-01-03
DD105237A5 (en)	1974-04-12
SE401675B (en)	1978-05-22
ZA733760B (en)	1975-01-29
LU67786A1 (en)	1973-08-16
AU472528B2 (en)	1976-05-27
AR208500A1 (en)	1977-02-15
JPS4961195A (en)	1974-06-13
BE819177R (en)	1975-02-26
JPS5943475B2 (en)	1984-10-22
FI57417B (en)	1980-04-30
DK152050C (en)	1988-07-18
BE800868A (en)	1973-12-13
NL184836B (en)	1989-06-16
FR2187356B1 (en)	1977-01-28
ATA508673A (en)	1976-03-15
FR2187356A1 (en)	1974-01-18
DK152050B (en)	1988-01-25
AU5651173A (en)	1974-12-05

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