CS236786B2 - Processing of ergoline derivative aryled in position 1 - Google Patents

Processing of ergoline derivative aryled in position 1 Download PDF

Info

Publication number
CS236786B2
CS236786B2 CS831070A CS107083A CS236786B2 CS 236786 B2 CS236786 B2 CS 236786B2 CS 831070 A CS831070 A CS 831070A CS 107083 A CS107083 A CS 107083A CS 236786 B2 CS236786 B2 CS 236786B2
Authority
CS
Czechoslovakia
Prior art keywords
group
methyl
hydrogen
hydroxy
compounds
Prior art date
Application number
CS831070A
Other languages
Czech (cs)
English (en)
Inventor
Georg Bolliger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CS236786B2 publication Critical patent/CS236786B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS831070A 1982-02-17 1983-02-17 Processing of ergoline derivative aryled in position 1 CS236786B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH98782 1982-02-17

Publications (1)

Publication Number Publication Date
CS236786B2 true CS236786B2 (en) 1985-05-15

Family

ID=4199836

Family Applications (1)

Application Number Title Priority Date Filing Date
CS831070A CS236786B2 (en) 1982-02-17 1983-02-17 Processing of ergoline derivative aryled in position 1

Country Status (19)

Country Link
JP (1) JPS58152884A (de)
AU (1) AU1142083A (de)
BE (1) BE895898A (de)
CS (1) CS236786B2 (de)
DD (1) DD209458A5 (de)
DE (1) DE3304361A1 (de)
DK (1) DK66483A (de)
ES (1) ES8407060A1 (de)
FI (1) FI830462L (de)
FR (1) FR2521562B1 (de)
GB (1) GB2115811B (de)
GR (1) GR79562B (de)
IT (1) IT1197578B (de)
NL (1) NL8300558A (de)
NO (1) NO830482L (de)
PL (1) PL240608A1 (de)
PT (1) PT76242B (de)
SE (1) SE8300865L (de)
ZA (1) ZA831089B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734501A (en) * 1985-10-01 1988-03-29 Eli Lilly And Company N-alkylation of dihydrolysergic acid
GB0808326D0 (en) * 2008-05-08 2008-06-18 E Therapeutics Plc Compositions and methods for the treatment of fybromyalgia

Also Published As

Publication number Publication date
GB2115811A (en) 1983-09-14
IT1197578B (it) 1988-12-06
DK66483D0 (da) 1983-02-15
PT76242A (en) 1983-03-01
FI830462A7 (fi) 1983-08-18
DD209458A5 (de) 1984-05-09
NL8300558A (nl) 1983-09-16
PL240608A1 (en) 1984-10-08
GB2115811B (en) 1985-08-14
ZA831089B (en) 1984-09-26
SE8300865D0 (sv) 1983-02-16
FR2521562A1 (fr) 1983-08-19
PT76242B (en) 1986-01-10
SE8300865L (sv) 1983-08-18
ES519811A0 (es) 1984-08-16
IT8347734A0 (it) 1983-02-17
FR2521562B1 (fr) 1985-10-25
DK66483A (da) 1983-08-18
FI830462A0 (fi) 1983-02-10
GB8304011D0 (en) 1983-03-16
DE3304361A1 (de) 1983-08-25
JPS58152884A (ja) 1983-09-10
BE895898A (fr) 1983-08-16
ES8407060A1 (es) 1984-08-16
NO830482L (no) 1983-08-18
AU1142083A (en) 1983-08-25
GR79562B (de) 1984-10-30
FI830462L (fi) 1983-08-18

Similar Documents

Publication Publication Date Title
US4721723A (en) Anti-depressant crystalline paroxetine hydrochloride hemihydrate
RU2056420C1 (ru) Производные 1,4-бензодиоксана или их соли и способ их получения
LU81453A1 (fr) Nouveaux derives de l'indole,leur preparation et leur application comme medicaments
EP0103497A1 (de) Xanthinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
LU86435A1 (fr) Nouveaux derives du morphinane et de la morphine,leur preparation,leur application comme medicaments et les compositions pharmaceutiques les contenant
KR20240132439A (ko) 트립타민 유도체의 제조 방법
EP0373998A1 (de) Propenonoximether, Verfahren zu dessen Herstellung sowie diese enthaltende Arzneinmittel
FR2531707A1 (fr) Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
EP0538080A1 (de) 4-Aminomethylpiperidine, Verfahren zur Herstellung und Anwendung in der Therapie
CA2153195C (fr) Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA1228359A (fr) Procede de preparation de nouveaux derives de la quinoleine
EP0564358B1 (de) 3-Aminochroman-Spiroderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CA1095047A (fr) Procede de preparation de nouveaux derives du 1,4- benzodioxane
FR2468370A1 (fr) Nouvelles pyridothienotriazines et leur procede de preparation
EP1399422A2 (de) Neue kristalline formen von 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl] -1-hydroxybutyl] -a,a-dimethylbenzenessigsäure und ihre chlorwasserstoffsalze
AU2001278094A1 (en) Novel crystalline forms of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperindinyl]-1-hydroxybutyl]-alpha, alpha-dimethylbenzene acetic acid and its hydrochloride
BE1000039A4 (fr) Nouvelles 8 alpha-acylamino-ergolines, leur preparation et leur utilisation comme medicaments.
CS236786B2 (en) Processing of ergoline derivative aryled in position 1
FR2549058A1 (fr) Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2753970A1 (fr) Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
CA2317515A1 (en) Oxazole derivatives as serotonin-1a receptor agonists
WO2001029031A1 (en) Process for the preparation of paroxetine
EP0632035B1 (de) Aminoalkylchomone, Verfahren für ihre Herstellung und die enthaltende pharmazeutische Zusammensetzungen
EP0419297B1 (de) Verfahren zur Trennung optischer Isomere von Derivaten des 1,4-Dihydropyridins
JPH02169572A (ja) ジヒドロピリジンアミド及びその生理学的に許容し得る塩