CS264699B1 - 2-nitrophenol-4- (N, 3'-carboxyphenyl) sulfonamide; - Google Patents

2-nitrophenol-4- (N, 3'-carboxyphenyl) sulfonamide; Download PDF

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CS264699B1
CS264699B1 CS881300A CS130088A CS264699B1 CS 264699 B1 CS264699 B1 CS 264699B1 CS 881300 A CS881300 A CS 881300A CS 130088 A CS130088 A CS 130088A CS 264699 B1 CS264699 B1 CS 264699B1
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Czechoslovakia
Prior art keywords
carboxyphenyl
sulfonamide
nitrophenol
formula
mol
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CS881300A
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Czech (cs)
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CS130088A1 (en
Inventor
Pavel Ing Buzik
Oldrich Ing Filip
Karel Lasak
Josef Dipl Tech Zaloudek
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Buzik Pavel
Filip Oldrich
Karel Lasak
Zaloudek Josef
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Application filed by Buzik Pavel, Filip Oldrich, Karel Lasak, Zaloudek Josef filed Critical Buzik Pavel
Priority to CS881300A priority Critical patent/CS264699B1/en
Publication of CS130088A1 publication Critical patent/CS130088A1/en
Publication of CS264699B1 publication Critical patent/CS264699B1/en

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Abstract

Řešení spadá do oblasti chemie organických barviv. Cílem řešení je sloučenina 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamid a způsob její přípravy. Způsob přípravy 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamidu vzorce I spočívá v tom, že se 2-nitrochlorbenzen-4- -(N,3-'karboxyfenyI)sulfonamid nechá reagovat s hydroxidem sodným ve vodném prostředí při teplotě 95 až 120 °C a při pH 11 až 14.The solution falls into the field of organic dye chemistry. The aim of the solution is the compound 2-nitrophenol-4-(N,3-carboxyphenyl)sulfonamide and a method for its preparation. The method for preparing 2-nitrophenol-4-(N,3-carboxyphenyl)sulfonamide of formula I consists in reacting 2-nitrochlorobenzene-4-(N,3-carboxyphenyl)sulfonamide with sodium hydroxide in an aqueous medium at a temperature of 95 to 120 °C and at a pH of 11 to 14.

Description

(57) Řešení spadá do oblasti chemie organických barviv. Cílem řešení je sloučenina 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamid a způsob její přípravy. Způsob přípravy 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamidu vzorce I(57) The solution falls within the field of organic dye chemistry. The object of the invention is 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide and a process for its preparation. A process for the preparation of 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide of formula I

OHOH

NO, [Oj cooh /NO, [Ooh cooh /

so2-nh—/Qý (i) spočívá v tom, že se 2-nitrochlorbenzen-4-(N,3-'karboxyfenyI)sulfonamid nechá reagovat s hydroxidem sodným ve vodném prostředí při teplotě 95 až 120 °C a při pH 11 až 14. 2- nitro (i) is characterized in that 2-nitrochlorobenzene-4- (N, 3-carboxyphenyl) sulfonamide is reacted with sodium hydroxide in an aqueous medium at a temperature of 95 to 120 ° C and a pH of 11 to 14.

CS 264 699 BlCS 264 699 Bl

IAND

Vynález se týká 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamidu a způsobu jeho výroby.The present invention relates to 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide and to a process for its preparation.

Byla připravena sloučenina 2-nitrofenol-4-(N,3-'karboxyfenyl)sulfonamid, která může sloužil k dalším syntézám v oblasti chemie organických barviv.The compound 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide was prepared, which may serve for further syntheses in the field of organic dye chemistry.

Způsob přípravy 2-nitrófenol-4-(N,3-karboxyfenyl)sulfonámidu vzorce IA process for the preparation of 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide of formula I

spočívá v tom, že se 2-nitrochlorbenzen-4-(N,3-karboxyfenyl)sulfonamid nechá reagovat s hydroxidem sodným ve vodném prostředí při teplotě 95 až 120 °C, s výhodou při teplotě 110 °C, a pH 11 až 14. Průběh konverze je téměř kvantitativní, s minimem vedlejších reakcí.characterized in that 2-nitrochlorobenzene-4- (N, 3-carboxyphenyl) sulfonamide is reacted with sodium hydroxide in an aqueous medium at a temperature of 95 to 120 ° C, preferably at 110 ° C, and a pH of 11 to 14. The conversion process is almost quantitative, with a minimum of side reactions.

Claims (2)

PŘEDMĚTSUBJECT 1. 2-aminofenol-4-(N,3-karboxyfenyl)sulfonamid vzorce IA 2-aminophenol-4- (N, 3-carboxyphenyl) sulfonamide of formula I Po izolaci se získá prakticky čistá látka vzorceAfter isolation, a practically pure compound of the formula is obtained I s teplotou tání 242 až 243 °C, s výtěžkemMp 242-243 ° C, yield 99 % teorie.99% of theory. Provedení vynálezů upřesňuje dále uvedený příklad.The invention is illustrated by the following example. PříkladExample 35,7 g 100% 2-nitrochlorbenzen-4-(N,3-karboxyfenyljsulfonainidu (0,1 mol) se suspenduje ve 150 ml vody, přidá se 19,2 g hydroxidu sodného 100% ve formě roztoku o koncentraci c(NaOH) = 100 mol/1 a nechá se reagovat při teplotě 110°C v laboratorním autoklávu při pH 11 až 14 po dobu 6 hodin.Suspend 35.7 g of 100% 2-nitrochlorobenzene-4- (N, 3-carboxyphenyl) sulfonainide (0.1 mol) in 150 ml of water, add 19.2 g of 100% sodium hydroxide as a c (NaOH) solution. = 100 mol / l and reacted at 110 ° C in a laboratory autoclave at pH 11-14 for 6 hours. Potom se reakční směs ochladí na teplotu 20 až 30 °C a pomalu, za stálého míchání, se vykyselí kyselinou chlorovodíkovou o koncentraci c(HCl) = 9 mol/1 na pH 1.The reaction mixture was then cooled to 20-30 ° C and acidified slowly, with stirring, with c (HCl) = 9 mol / l hydrochloric acid to pH 1. Získaný pevný podíl se izoluje filtrací. Filtrační koláč se promyje studenou vodou do ztráty kyselé reakce filtrátů.The resulting solid was collected by filtration. The filter cake is washed with cold water until the acidic reaction of the filtrates is lost. Syntézou se získá 33,5 g 100% 2-nitrofenol-4-(N,3-'karboxyfenyl)sulfamidu o t. t. 242 až 243 °C.Synthesis yielded 33.5 g of 100% 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfamide, m.p. 242-243 ° C. YNALEZUYNALEZU 2. Způsob přípravy 2-nitrofenol-4-(N,3-karboxyfenyl)sulfonamid vzorce 1 podle bodu 1, vyznačený tím, že se ve vodném prostředí nechá reagovat 2-nitrochlorbenzen-4-(N,3-karboxyfenyljsulfonamid s hydroxidem sodným při teplotě 95 až 120 °C a pH 11 až 14.2. A process for the preparation of 2-nitrophenol-4- (N, 3-carboxyphenyl) sulfonamide of the formula I according to claim 1, which comprises reacting 2-nitrochlorobenzene-4- (N, 3-carboxyphenyl) sulfonamide with sodium hydroxide in an aqueous medium. temperature 95 to 120 ° C and pH 11 to 14.
CS881300A 1988-03-01 1988-03-01 2-nitrophenol-4- (N, 3'-carboxyphenyl) sulfonamide; CS264699B1 (en)

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CS881300A CS264699B1 (en) 1988-03-01 1988-03-01 2-nitrophenol-4- (N, 3'-carboxyphenyl) sulfonamide;

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CS264699B1 true CS264699B1 (en) 1989-08-14

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