CS276822B6 - Mixture containing antitussive and process for preparing thereof - Google Patents

Abstract

solution the relates to mixtures with content antitusic- ky efficient substances, which It consists from for the inflated water extract from root Ibisa medical (Althaea officinalis L. ) and after Grassland dextrin within mutual wt. ratio food dextrin to dry matter extract 0.35 until 0.50 : 1 within as a powder. mixture the prepare maceration crushed ko renovate Marshmallow medical in distilled water aqueous extract Sá centrifuged . concentrated . added the to it food- dextrin, solution the homogenized and dried. mixture my exploitation within farmaceutlckora and food industry.

Description

. The invention relates to a mixture containing an antitussive active substance (mucus) as well as to a process for its preparation from the root of the medical ibis (Althaea officinalis L.).

The root of the medical ibis is part of various tea blends. especially with antitussive and expectorant effect. Water extracts (teas) or syrups are most often prepared for use. The disadvantage of aqueous extracts is that they can only be prepared at the time of need, as there is a risk of microbial contamination of the extract during prolonged storage. Powder extracts from hibiscus root, resp. from the roots of other medicinal plants have not yet been described in the literature.

The essence of the mixture containing the antitussive active substance according to the invention consists in that it consists of a concentrated aqueous extract of hibiscus root of medical and food dextrin, in mutual mass, the ratio of food dextrin to dry matter of the extract 0.35 to 0.50: 1, in powder form. .

The essence of the method of preparation of said extract is that the crushed hibiscus roots are macerated in distilled water, the aqueous extract is centrifuged and concentrated, food dextrin is added in an amount of 35 to 50% by weight, to dry matter of the extract, homogenized and dried. , preferably in a spray device.

It has been found to be advantageous if the crushed roots are macerated in distilled water at a temperature of 15 to 25 ° C for 2 to 4 hours and if the spraying is carried out at an inlet temperature of 180 to 220 ° C.

The extract obtained is a light brown powder which, in addition to the biologically active mucilage, contains starch, pectin substances, proteins, monosaccharides, amino acids and minerals. .

The mixture (powder extract) containing the antitussive active mucus according to the invention can be stored without the risk of microbial contamination, is easy to adjust and is easy to package.

The following examples illustrate but do not limit the scope of the invention.

Example 1.

Ground roots (15 kg) of hibiscus (Althaea officinalis L.), size 1 to 5 mm, are macerated in distilled water (240 l) for 2 h at 25 ° C with constant stirring. The aqueous extract was centrifuged, the dry matter (1.6%) was determined and concentrated in vacuo to a volume of 20 L. A solution of food grade dextrin was added to the concentrated extract. which is prepared by dissolving 3 kg of dextrin in 2 l of hot distilled water with stirring. After thorough homogenization, the solution is spray-dried at an inlet temperature of 190 ° C. 6.5 kg of a light brown powder are obtained.

Example 2

Ground roots (15 kg) of hibiscus (Althaea officinalis L.), 1 to 5 mm in size, are macerated in distilled water (240

1) at 15 ° C with stirring for 4 h. The aqueous extract was filtered and concentrated in vacuo to a volume of 18 L. A solution of food grade dextrin was prepared to the concentrated extract, which was prepared by dissolving 2.5 kg of dextrin in 2 L of hot distilled water with stirring. After thorough homogenization, the solution is spray-dried at an inlet temperature of 210 ° C. 6 kg of a light brown powder are obtained.

Due to the powder form of the extract and the content of antitussively active mucus, said extract can be used in the food industry, especially in the production of confectionery products with an antifungal effect.

Claims (4)

PATENT CLAIMS A composition comprising an antitussive active substance, characterized in that it consists of a concentrated aqueous extract of hibiscus root (Althaea officinalis L.) and food dextrin, in a mutual mass, a food dextrin to extract dry matter ratio of 0.35 to 0.50. : 1, in the form of a powder. 2. A process for the preparation of a mixture containing an antitussive active substance according to item 1, characterized in that the crushed roots of hibiscus (Althaea officinalis L.) are macerated in distilled water, the solid components are removed from the aqueous extract, the extract is concentrated, added to it food dextrin in an amount of 35 to 50% by weight, on the dry matter of the extract, the solution is homogenized and dried, preferably by spraying. 3. The preparation method according to item 2, characterized in that the crushed roots are macerated at a temperature of 15 to 25 ° C for 2 to 4 hours. 4. The preparation method according to item 2, characterized in that the solution is spray-dried at an inlet temperature of 180 to 220 ° C. End of document