CS346491A3 - Complexes containing s-(+)-phenylalkanoic acids and alpha-amino acids - Google Patents

Complexes containing s-(+)-phenylalkanoic acids and alpha-amino acids

Info

Publication number
CS346491A3
CS346491A3 CS913464A CS346491A CS346491A3 CS 346491 A3 CS346491 A3 CS 346491A3 CS 913464 A CS913464 A CS 913464A CS 346491 A CS346491 A CS 346491A CS 346491 A3 CS346491 A3 CS 346491A3
Authority
CS
Czechoslovakia
Prior art keywords
acids
alpha
amino acids
complexes containing
phenylalkanoic
Prior art date
Application number
CS913464A
Other languages
Czech (cs)
Inventor
Henrich Hasko Prof Dr Paradies
Original Assignee
Medice
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6418339&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS346491(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medice filed Critical Medice
Publication of CS346491A3 publication Critical patent/CS346491A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel complexes of S-(+)-ibuprofen and amino acids are described. These complexes have anti-inflammatory, antipyretic and antimicrobial properties and also analgesic effects. <IMAGE>
CS913464A 1990-11-15 1991-11-15 Complexes containing s-(+)-phenylalkanoic acids and alpha-amino acids CS346491A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4036458 1990-11-15

Publications (1)

Publication Number Publication Date
CS346491A3 true CS346491A3 (en) 1992-06-17

Family

ID=6418339

Family Applications (1)

Application Number Title Priority Date Filing Date
CS913464A CS346491A3 (en) 1990-11-15 1991-11-15 Complexes containing s-(+)-phenylalkanoic acids and alpha-amino acids

Country Status (16)

Country Link
EP (1) EP0486045B1 (en)
JP (1) JPH0656737A (en)
KR (1) KR920009774A (en)
CN (1) CN1061404A (en)
AT (1) ATE137733T1 (en)
AU (1) AU8790591A (en)
BG (1) BG95490A (en)
BR (1) BR9104996A (en)
CA (1) CA2055683A1 (en)
CS (1) CS346491A3 (en)
DE (2) DE59107790D1 (en)
HU (1) HUT59656A (en)
MX (1) MX9102088A (en)
NZ (1) NZ240617A (en)
PL (1) PL292413A1 (en)
ZA (1) ZA919077B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT59653A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alcanoic acids and alpha-hydroxy-alcanoic acids and pharmaceutical compositions containing them as active components
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
JPH06510020A (en) * 1991-03-29 1994-11-10 ユニバーシティ・オブ・フロリダ Targeted drug delivery via hybrid phosphate ester derivatives
EP0672030B1 (en) * 1992-12-02 1997-04-16 Knoll AG Process for preparing substantially pure enantiomers of phenylpropionic acids
IT1272149B (en) * 1993-03-26 1997-06-11 Zambon Spa PHARMECEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY
IT1264855B1 (en) * 1993-06-21 1996-10-17 Zambon Spa PHARMACEUTICAL COMPOSITIONS CONTAINING S (+) - 2- (4-ISOBUTYLPHENYL) PROPIONIC ACID SALTS WITH BASIC AMINO ACIDS
CA2327285C (en) * 1998-05-15 2005-06-14 Warner-Lambert Company Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
AR057882A1 (en) 2005-11-09 2007-12-26 Novartis Ag DOUBLE ACTION COMPOUNDS OF ANGIOTENSIN RECEPTOR BLOCKERS AND NEUTRAL ENDOPEPTIDASE INHIBITORS
CN101455653B (en) * 2007-12-13 2013-03-06 天津医科大学 Arginine ibuprofen oral disintegrating tablets and preparation method thereof
CN116621689A (en) * 2023-04-24 2023-08-22 山东省药学科学院 A kind of L-lysine-biphenylacetate and its preparation method and application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE3639038C2 (en) * 1986-11-14 1997-02-06 Helmut Dr Lukas Use of S - (+) - ibuprofen for rapid treatment of human pain
ATE128452T1 (en) * 1989-10-17 1995-10-15 Merck & Co Inc S(+)-IBUPROFEN-L-AMINO ACID AND S(+)-IBUPROFEN-D-AMINO ACID AS ANALGESICS WITH GREATER PHARMACOLOGICAL POTENTIAL.

Also Published As

Publication number Publication date
JPH0656737A (en) 1994-03-01
BR9104996A (en) 1992-06-23
ZA919077B (en) 1992-08-26
PL292413A1 (en) 1993-01-25
DE4137675A1 (en) 1992-05-21
BG95490A (en) 1993-12-24
EP0486045B1 (en) 1996-05-08
ATE137733T1 (en) 1996-05-15
CN1061404A (en) 1992-05-27
NZ240617A (en) 1994-12-22
DE59107790D1 (en) 1996-06-13
CA2055683A1 (en) 1992-05-16
HU913571D0 (en) 1992-01-28
KR920009774A (en) 1992-06-25
MX9102088A (en) 1993-01-01
HUT59656A (en) 1992-06-29
EP0486045A3 (en) 1992-12-09
EP0486045A2 (en) 1992-05-20
AU8790591A (en) 1992-05-21

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