CS451386A2 - Method of new n-(2-aminoacylamido-2-deoxyhexosyl)-amides,carbamates and ureas production - Google Patents

Method of new n-(2-aminoacylamido-2-deoxyhexosyl)-amides,carbamates and ureas production

Info

Publication number
CS451386A2
CS451386A2 CS864513A CS451386A CS451386A2 CS 451386 A2 CS451386 A2 CS 451386A2 CS 864513 A CS864513 A CS 864513A CS 451386 A CS451386 A CS 451386A CS 451386 A2 CS451386 A2 CS 451386A2
Authority
CS
Czechoslovakia
Prior art keywords
denotes hydrogen
carbon atoms
alkyl radical
hydrogen
new
Prior art date
Application number
CS864513A
Other languages
English (en)
Other versions
CS270209B2 (en
Inventor
Oswald Dr Lockhoff
Yutaka Dr Hayauchi
Peter Dr Stadler
Klaus Georg Dr Stunkel
Gert Dr Streissle
Arnold Dr Paessens
Volker Dr Klimetzek
Hans-Joachim Dr Zeiler
Karl Georg Dr Metzger
Hein-Peter Dr Kroll
Helmut Prof Dr Brunner
Klaus Dr Schaller
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS451386A2 publication Critical patent/CS451386A2/cs
Publication of CS270209B2 publication Critical patent/CS270209B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
  • Pyrrole Compounds (AREA)
CS864513A 1985-06-20 1986-06-18 Method of new n-(2-aminoacylamido-2-desoxyhexosyl)-amides,carbamates and ureas production CS270209B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853521994 DE3521994A1 (de) 1985-06-20 1985-06-20 N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
CS451386A2 true CS451386A2 (en) 1989-10-13
CS270209B2 CS270209B2 (en) 1990-06-13

Family

ID=6273684

Family Applications (1)

Application Number Title Priority Date Filing Date
CS864513A CS270209B2 (en) 1985-06-20 1986-06-18 Method of new n-(2-aminoacylamido-2-desoxyhexosyl)-amides,carbamates and ureas production

Country Status (21)

Country Link
US (1) US4855283A (cs)
EP (1) EP0206037B1 (cs)
JP (1) JPH07116207B2 (cs)
KR (1) KR930011281B1 (cs)
CN (1) CN86104185A (cs)
AT (1) ATE71631T1 (cs)
AU (1) AU564222B2 (cs)
CA (1) CA1289952C (cs)
CS (1) CS270209B2 (cs)
DE (2) DE3521994A1 (cs)
DK (1) DK287886A (cs)
ES (2) ES8801769A1 (cs)
FI (1) FI84833C (cs)
GR (1) GR861574B (cs)
HU (1) HU206123B (cs)
IE (1) IE58918B1 (cs)
IL (1) IL79126A (cs)
NO (1) NO166002C (cs)
PH (1) PH26775A (cs)
PT (1) PT82796B (cs)
ZA (1) ZA864571B (cs)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3812681A1 (de) * 1988-04-16 1989-11-02 Bayer Ag Substituierte n-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US5977336A (en) * 1993-03-16 1999-11-02 St. Louis University High molecular weight surface proteins of non-typeable haemophilus
JPH09501940A (ja) * 1993-08-30 1997-02-25 バイエル・アクチエンゲゼルシヤフト ２−アミノアシルアミノ−２−デオキシ糖類のグリコシルアミド類
US6361779B1 (en) 1993-11-08 2002-03-26 Aventis Pasteur Limited Transferrin receptor genes
ES2270420T3 (es) 1993-11-08 2007-04-01 Sanofi Pasteur Limited Genes receptores de la transferrina de haemophilus.
US6764682B1 (en) * 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6335018B1 (en) 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
CA2433502A1 (en) 1995-05-04 1996-11-07 Aventis Pasteur Limited Acellular pertussis vaccines and methods of preparation thereof
US5827654A (en) * 1995-05-08 1998-10-27 University Of Toronto Basal body rod protein genes of campylobacter
US5780606A (en) * 1995-06-07 1998-07-14 Connaught Laboratories Limited Neisseria meningitidis capsular polysaccharide conjugates
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
US6290971B1 (en) * 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
US6048539A (en) * 1995-11-02 2000-04-11 Connaught Laboratories Limited Lactoferrin receptor protein
FR2746643B1 (fr) * 1996-04-01 1998-06-12 Techni Pharma Nouvelles compositions laxatives et leur procede de fabrication
BR9710460A (pt) 1996-07-02 1999-08-17 Connaught Lab Composi-Æo imunolÄgica multi-valente e seu uso em vacinas
US6042820A (en) 1996-12-20 2000-03-28 Connaught Laboratories Limited Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
FR2762787B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1
FR2762788B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique
BR9809381A (pt) * 1997-04-30 2000-07-04 Merieux Oravax Composição de vacina anti-helicobacter compreendendo um adjuvante do tipo th1
US5977337A (en) * 1997-06-03 1999-11-02 Connaught Laboratories Limited Lactoferrin receptor genes of Moraxella
US7459524B1 (en) * 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
US7785609B1 (en) 1999-03-16 2010-08-31 Sanofi Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
US6335182B1 (en) 1999-03-16 2002-01-01 Aventis Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
US7241449B1 (en) 1999-04-12 2007-07-10 Aventis Pasteur Limited Transferrin receptor genes of moraxella
JP2003512829A (ja) 1999-10-22 2003-04-08 アヴェンティス パストゥール リミテッド 改変型ｇｐ１００およびその使用
GB0000891D0 (en) * 2000-01-14 2000-03-08 Allergy Therapeutics Ltd Formulation
CA2408328C (en) 2000-05-10 2012-04-17 Aventis Pasteur Limited Immunogenic polypeptides encoded by mage minigenes and uses thereof
AUPS143402A0 (en) * 2002-03-28 2002-05-09 Alchemia Pty Ltd Anomeric derivatives of monosaccharides
TW200509968A (en) 2002-11-01 2005-03-16 Elan Pharm Inc Prevention and treatment of synucleinopathic disease
US8506959B2 (en) 2002-11-01 2013-08-13 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
ATE480258T1 (de) * 2002-11-26 2010-09-15 Eurocine Vaccines Ab Neue adjuvant auf der basis von aminen
CA2526900C (en) 2003-05-19 2015-11-24 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in lewy body disease
US7358331B2 (en) 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
MX2007001679A (es) 2004-08-09 2007-05-23 Elan Pharm Inc Prevencion y tratamiento de la enfermedad sinucleinopatica y amiloidogenica.
CN101374551B (zh) * 2006-01-26 2013-06-12 辉瑞产品公司 新的糖脂佐剂组合物
PL1991266T3 (pl) * 2006-01-26 2013-11-29 Zoetis Services Llc Nowe kompozycje adiuwantów glikolipidowych
JP5558834B2 (ja) 2007-02-23 2014-07-23 ヤンセン アルツハイマー イミュノセラピー シヌクレイノパチーおよびアミロイド形成疾患（ａｍｙｌｏｉｄｏｇｅｎｉｃｄｉｓｅａｓｅ）の予防および処置
ES2546863T3 (es) 2007-02-23 2015-09-29 Prothena Biosciences Limited Prevención y tratamiento de enfermedad sinucleinopática y amiloidogénica
GB2450088A (en) * 2007-06-11 2008-12-17 Diosamine Dev Corp Optionally modified monosaccharides with imine/iminium or glycosidic amine/ammonium group for use in modifying the level of cytokines & in therapy
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
ES2544679T3 (es) 2007-12-28 2015-09-02 Prothena Biosciences Limited Tratamiento y profilaxis de la amiloidosis
EP2196196A1 (en) 2008-12-10 2010-06-16 Medipol S.A. Compound, medicament, vaccine composition and nanocapsules
GB201000196D0 (en) * 2010-01-07 2010-02-24 Galvez Julian M Novel combination
CN107641151B (zh) 2010-05-14 2021-10-01 百深公司 Ospa嵌合体及其在疫苗中的用途
RU2015106742A (ru) 2012-07-27 2016-09-20 Бакстер Интернэшнл Инк. Композиции, содержащие химерные молекулы ospa и способы их применения
CN104628802B (zh) * 2013-11-07 2017-01-18 北大方正集团有限公司 从发酵液中提取并纯化尼莫克汀的方法
EP3071974A2 (en) 2013-11-19 2016-09-28 Prothena Biosciences Limited Monitoring immunotherapy of lewy body disease from constipation symptoms
EP3028711A1 (en) * 2014-12-05 2016-06-08 Gubra ApS Molecular building blocks capable of assembling carbohydrate derivatives, fatty acid residues and peptides
US10456459B2 (en) * 2015-07-20 2019-10-29 Zoetis Services Llc Liposomal adjuvant compositions
HUE054422T2 (hu) * 2015-07-20 2021-09-28 Zoetis Services Llc Liposzómás adjuváns készítmények

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3213650A1 (de) * 1982-04-14 1983-10-27 Bayer Ag, 5090 Leverkusen N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr
DE3344257A1 (de) * 1983-12-07 1985-06-13 Bayer Ag, 5090 Leverkusen Substituierte o-acyl-glycosylamide, verfahren zu iherer herstellung sowie ihre verwendung

Also Published As

Publication number Publication date
JPS61293991A (ja) 1986-12-24
EP0206037A3 (en) 1988-02-03
FI84833C (fi) 1992-01-27
AU564222B2 (en) 1987-08-06
PT82796B (pt) 1988-12-15
JPH07116207B2 (ja) 1995-12-13
ES556287A0 (es) 1988-02-16
US4855283A (en) 1989-08-08
PH26775A (en) 1992-10-13
CS270209B2 (en) 1990-06-13
NO166002C (no) 1991-05-15
NO862199L (no) 1986-12-22
PT82796A (en) 1986-07-01
FI862619A0 (fi) 1986-06-18
ES8801769A1 (es) 1988-02-16
IL79126A0 (en) 1986-09-30
FI84833B (fi) 1991-10-15
AU5897986A (en) 1986-12-24
DE3521994A1 (de) 1987-01-02
ES8900231A1 (es) 1989-04-16
HUT41049A (en) 1987-03-30
ATE71631T1 (de) 1992-02-15
HU206123B (en) 1992-08-28
ZA864571B (en) 1987-02-25
EP0206037B1 (de) 1992-01-15
DK287886A (da) 1986-12-21
CA1289952C (en) 1991-10-01
IL79126A (en) 1991-09-16
KR930011281B1 (en) 1993-11-29
KR870000354A (ko) 1987-02-18
DE3683410D1 (de) 1992-02-27
NO862199D0 (no) 1986-06-03
CN86104185A (zh) 1987-04-08
EP0206037A2 (de) 1986-12-30
IE861636L (en) 1986-12-20
GR861574B (en) 1986-10-17
FI862619A7 (fi) 1986-12-21
NO166002B (no) 1991-02-04
DK287886D0 (da) 1986-06-19
IE58918B1 (en) 1993-12-01
ES557729A0 (es) 1989-04-16

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