CS528085A2 - Zpusob pripravy sloucenin s n demethylmorfinanovym skeletem - Google Patents

Zpusob pripravy sloucenin s n demethylmorfinanovym skeletem

Info

Publication number
CS528085A2
CS528085A2 CS855280A CS528085A CS528085A2 CS 528085 A2 CS528085 A2 CS 528085A2 CS 855280 A CS855280 A CS 855280A CS 528085 A CS528085 A CS 528085A CS 528085 A2 CS528085 A2 CS 528085A2
Authority
CS
Czechoslovakia
Prior art keywords
group
hydrogen atom
carbon atoms
benzoyloxy
acyloxy
Prior art date
Application number
CS855280A
Other languages
English (en)
Other versions
CS251792B2 (en
Inventor
Sandor Dr Hosztafi
Tibor Dr Timar
Julianna Nagy
Ilona Fabian
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of CS528085A2 publication Critical patent/CS528085A2/cs
Publication of CS251792B2 publication Critical patent/CS251792B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Photolithography (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Stringed Musical Instruments (AREA)
  • Finger-Pressure Massage (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Cephalosporin Compounds (AREA)
CS855280A 1984-07-17 1985-07-16 Method of compouns preparation with n-demethylmorphinane skeleton CS251792B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842774A HU197750B (en) 1984-07-17 1984-07-17 Process for n-demethylation of morphine alkaloids

Publications (2)

Publication Number Publication Date
CS528085A2 true CS528085A2 (en) 1986-12-18
CS251792B2 CS251792B2 (en) 1987-08-13

Family

ID=10961043

Family Applications (1)

Application Number Title Priority Date Filing Date
CS855280A CS251792B2 (en) 1984-07-17 1985-07-16 Method of compouns preparation with n-demethylmorphinane skeleton

Country Status (18)

Country Link
EP (1) EP0168686B1 (cs)
JP (1) JPS6193184A (cs)
AT (1) ATE41933T1 (cs)
BG (1) BG44029A3 (cs)
CS (1) CS251792B2 (cs)
DD (1) DD235639A5 (cs)
DE (1) DE3569244D1 (cs)
DK (1) DK322385A (cs)
ES (1) ES8603716A1 (cs)
FI (1) FI81583C (cs)
HU (1) HU197750B (cs)
IL (2) IL75509A0 (cs)
IN (1) IN166255B (cs)
NO (1) NO161915C (cs)
PL (1) PL254552A1 (cs)
RO (1) RO91516B (cs)
SU (1) SU1398776A3 (cs)
YU (1) YU45264B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ611651A (en) * 2007-12-17 2014-11-28 Mallinckrodt Llc Sinomenine derivatives and processes for their synthesis
EP2222642B1 (en) * 2007-12-17 2014-02-12 Mallinckrodt LLC Process and compounds for the production of (+) opiates
CA2761287A1 (en) * 2009-05-12 2010-11-18 Board Of Regents The University Of Texas System Synthesis of morphine and related derivatives
ES2728701T3 (es) * 2010-07-16 2019-10-28 Mallinckrodt Llc (+)-Morfinanos como antagonistas del receptor 9 de tipo Toll y aplicaciones terapéuticas de los mismos
CN103917543A (zh) 2011-09-08 2014-07-09 马林克罗特有限公司 在不分离中间体的情况下制备生物碱

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA948198A (en) * 1967-08-04 1974-05-28 Gerhard Walther Production of cyclic amino compounds
DE2254298A1 (de) * 1972-11-06 1974-05-16 Boehringer Sohn Ingelheim Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
DE2727805A1 (de) * 1977-06-21 1979-01-04 Goedecke Ag Verfahren zur herstellung von oxynormorphon

Also Published As

Publication number Publication date
FI852779A0 (fi) 1985-07-15
EP0168686B1 (de) 1989-04-05
ES8603716A1 (es) 1986-01-16
DK322385A (da) 1986-01-18
NO852838L (no) 1986-01-20
HU197750B (en) 1989-05-29
IL75509A0 (en) 1985-10-31
EP0168686A1 (de) 1986-01-22
FI81583C (fi) 1990-11-12
FI81583B (fi) 1990-07-31
NO161915B (no) 1989-07-03
PL254552A1 (en) 1986-07-15
YU117485A (en) 1988-04-30
JPS6193184A (ja) 1986-05-12
RO91516A (ro) 1987-06-30
ES544385A0 (es) 1986-01-16
DE3569244D1 (en) 1989-05-11
SU1398776A3 (ru) 1988-06-15
BG44029A3 (en) 1988-09-15
CS251792B2 (en) 1987-08-13
DD235639A5 (de) 1986-05-14
IN166255B (cs) 1990-03-31
YU45264B (en) 1992-05-28
NO161915C (no) 1989-10-11
DK322385D0 (da) 1985-07-15
FI852779L (fi) 1986-01-18
HUT38645A (en) 1986-06-30
ATE41933T1 (de) 1989-04-15
IL78503A (en) 1990-01-18
RO91516B (ro) 1987-07-01

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