CS542383A2 - Method of daunorubicine's and doxorubicine's new morpholine derivatives production - Google Patents
Method of daunorubicine's and doxorubicine's new morpholine derivatives productionInfo
- Publication number
- CS542383A2 CS542383A2 CS835423A CS542383A CS542383A2 CS 542383 A2 CS542383 A2 CS 542383A2 CS 835423 A CS835423 A CS 835423A CS 542383 A CS542383 A CS 542383A CS 542383 A2 CS542383 A2 CS 542383A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- daunorubicine
- doxorubicine
- morpholine derivatives
- derivatives production
- new
- Prior art date
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 2
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 title 1
- 229960000975 daunorubicin Drugs 0.000 title 1
- 150000002780 morpholines Chemical class 0.000 title 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Anthracycline derivs. of formula (I) are new. R is COMe or CO.CH2OH; B is CN or OH, or (with the H atom attached to the same C) is oxo; R'' is H and R' is OH, or B plus R' are together an oxygen bridge. Pref. B is CN or completes oxo or O bridge.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS542383A2 true CS542383A2 (en) | 1989-07-12 |
| CS268512B2 CS268512B2 (en) | 1990-03-14 |
Family
ID=5399112
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Country Status (1)
| Country | Link |
|---|---|
| CS (2) | CS268512B2 (en) |
-
1983
- 1983-07-19 CS CS835423A patent/CS268512B2/en unknown
-
1984
- 1984-12-13 CS CS849740A patent/CS268514B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS268512B2 (en) | 1990-03-14 |
| CS974084A2 (en) | 1989-07-12 |
| CS268514B2 (en) | 1990-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0283165A3 (en) | Skin conditioning composition and method | |
| UA7140A1 (en) | Method for producing pyridine derivatives | |
| FI842479L (en) | ANSLUTNINGSLIST MED LOED-, SKRUV- OCH AVSKALNINGSFRIA ANSLUTNINGELEMENT MED POLYTROP LUFTSPALT FOER ANSLUT NING AV KABELLEDARE OCH LUFTKABLAR (INTAGNINGSKABLAR). | |
| YU75988A (en) | Process for obtaining 4-demetoxy-4-amino-anthracyclinones | |
| IL88798A0 (en) | Process and intermediates for the synthesis of 1,2-dioxetanes | |
| IL75133A (en) | Process for the preparation of 1,2-diacyl-s,n-glycerophosphocholines(or glycerophosphoethanolamines)and some novel intermediates therefor | |
| JPS5366442A (en) | Antitumors | |
| EP0228015A3 (en) | Antibiotic a 40926 mannosyl aglycon | |
| CS542383A2 (en) | Method of daunorubicine's and doxorubicine's new morpholine derivatives production | |
| SE8500845D0 (en) | PROCEDURE FOR THE PREPARATION OF GLYOXYLYLYL PERMIDINE AND ITS USE FOR PREPARATION OF 15-DEOXISPERGUALIN-RELATED COMPOUNDS | |
| EP0167980A3 (en) | Novel substrates for use in measuring the concentration of kallikrein in urine | |
| JPS57183783A (en) | Manufacture of cholesterol derivatives | |
| EP0439913A3 (en) | Manufacture of ketone derivatives of polyoxypropylene glycols | |
| EP0430484A3 (en) | Ketone derivatives of polyoxypropylene glycols | |
| AU580646B2 (en) | 13``-alkyl-17``-(3-aceloxy-propyl)-gonane | |
| HUT44997A (en) | Process for producing new cyclopentan derivatives | |
| IT1178507B (en) | New 11-deoxy-17-hydroxy -corticosterone ester(s) | |
| IL76150A (en) | Derivatives of aminochromancarboxylic acid and their preparation | |
| FR2222095A1 (en) | 3-Substd. tetrahydro-benzopyrano (3,4-c) pyridin-5-ones - bronchodilators for treating bronchial asthma | |
| DE3264330D1 (en) | Process for the preparation of cycloalkenon derivatives | |
| FR2648813B1 (en) | NEW TERPENIC DERIVATIVES, THEIR PREPARATION AND THEIR USE | |
| JPS545992A (en) | Dibenzoxopin derivatives and process for thier preparation | |
| HU177859B (en) | Composition of medium for detecting infection of bacteria producing ammonia | |
| RO96329A2 (en) | 1,1'-OXYBIS-4N-PHENOXYACETAMIDOBENZENE DERIVATIVES AND PREPARATION METHOD | |
| JPS531457A (en) | Counter |