CS8902302A2 - Method of beta-lactam derivatives production - Google Patents
Method of beta-lactam derivatives productionInfo
- Publication number
- CS8902302A2 CS8902302A2 CS230289A CS230289A CS8902302A2 CS 8902302 A2 CS8902302 A2 CS 8902302A2 CS 230289 A CS230289 A CS 230289A CS 230289 A CS230289 A CS 230289A CS 8902302 A2 CS8902302 A2 CS 8902302A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- alkyl
- benzyl
- phenyl
- straight
- cycloalkyl
- Prior art date
Links
- 150000003952 β-lactams Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000001174 sulfone group Chemical group 0.000 abstract 2
- 150000007649 L alpha amino acids Chemical class 0.000 abstract 1
- DBTDEFJAFBUGPP-UHFFFAOYSA-N Methanethial Chemical compound S=C DBTDEFJAFBUGPP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004350 aryl cycloalkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
4-Acylcephem sulphones and 3-acylpenam sulphones of formula (Ia) and (Ib) resp. and their salts are new: A = H; 1-12C straight or branched alkyl; 2-10C alkenyl; 6-10C aryl; 3-8C cycloalkyl; 5-8C cycloalkenyl; aralkyl, aralkenyl, aralkynyl or (cycloalkyl)alkyl in which the aryl cycloalkyl, alkyl, alkenyl and alkynyl gps. are as defined above; etc.R1 = (1) Cl, F, Br or I; (2) A as defined above; (3) O-A; (4) S(O)nA; (5) OC(O)A; (6) OSO2A; or (7) NHC(O)A or NH2; R1 and R11 each = 1-7C straight or branched alkyl, phenyl or benzyl; t = 0-3; R111 = 1-7C straight or branched alkyl, phenyl, benzyl, CH2CH2CO2H or CH2CH2CH2CO2H; Z = mono-, di- or tri-peptide composed of D- or L-alpha-aminoacids, namely Ala, Gly, Val, He, Leu, Phe or Pro, with the terminal amino gp. either free, or acylated by a gp. C(O)R111 or C(O)OR111; H, 1-4C alkyl, 1-4C alkanoyloxy or Cl, Br or F; R3 = H, 1-4C alkyl, 1-4C alkoxy, benzyl, halo or =CH2 or CHR1111; R1111 = 1-4C alkyl, phenyl, COOH or 1-4C alkoxycarbonyl; R1 = (1) A; (2) Cl or F; (3) O-A; (4) S(O)nA; (5) C(O)A, C(O) OA or CO2H; (6) CH2-O-A; (7) CH2S(O)nA; (8) CH2OC(O)A or CH2-O-Z; (9) CH2SC(O)A; (10) CH2-N(A)A1; (11) -CH2N(+)(A)(A1)(A11); or (12) -CH2NH-C(O)A or CH2-NH-Z; A1 = same or different A gp.; or NAA1 = heterocyclic ring; A11 = as for A1; or NA1A11 = heterocyclic ring; or NAA1A11 = aromatic heterocyclic ring.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8800701A GB2210334A (en) | 1987-10-02 | 1988-01-13 | Floating production system and vessel for undersea oil well |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS8902302A2 true CS8902302A2 (en) | 1991-03-12 |
| CS277027B6 CS277027B6 (en) | 1992-11-18 |
Family
ID=10629877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS230289A CS277027B6 (en) | 1988-01-13 | 1989-04-13 | Process for preparing beta-lactam derivatives |
Country Status (1)
| Country | Link |
|---|---|
| CS (1) | CS277027B6 (en) |
-
1989
- 1989-04-13 CS CS230289A patent/CS277027B6/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS277027B6 (en) | 1992-11-18 |
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