CU20060121A7 - TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS - Google Patents
TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORSInfo
- Publication number
- CU20060121A7 CU20060121A7 CU20060121A CU20060121A CU20060121A7 CU 20060121 A7 CU20060121 A7 CU 20060121A7 CU 20060121 A CU20060121 A CU 20060121A CU 20060121 A CU20060121 A CU 20060121A CU 20060121 A7 CU20060121 A7 CU 20060121A7
- Authority
- CU
- Cuba
- Prior art keywords
- hormones
- patch
- potentiators
- transdermal administration
- need
- Prior art date
Links
- 229940088597 hormone Drugs 0.000 title abstract 3
- 239000005556 hormone Substances 0.000 title abstract 3
- 230000035515 penetration Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000003623 enhancer Substances 0.000 abstract 2
- 230000036470 plasma concentration Effects 0.000 abstract 2
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 abstract 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 229960002568 ethinylestradiol Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
La invención se refiere a un parche que comprende una capa de droga con un bajo contenido de hormonas, como por ejemplo gestodeno, y opcionalmente un estrógeno (por ejemplo etinilestradiol). Al aplicar el parche a una mujer, se consiguen niveles de plasma de al menos 1,0 ng / ml de gestodeno en condiciones de estado estacionario sin necesidad de incorporar potenciadores de penetración ni mejoradores de permeación en la capa que contiene droga. También son satisfactorios los niveles en plasma de las hormonas que se consiguen durante todo un período de al menos 1 semana, haciendo que el parche se pueda aplicar para utilizarlo en anticoncepción femenina con el concepto de aplicar el parche una vez a la semana.The invention relates to a patch comprising a drug layer with a low content of hormones, such as, for example, signodene, and optionally an estrogen (for example ethinyl estradiol). By applying the patch to a woman, plasma levels of at least 1.0 ng / ml of signodene are achieved under steady state conditions without the need to incorporate penetration enhancers or permeation enhancers in the drug-containing layer. Plasma levels of hormones that are achieved over a period of at least 1 week are also satisfactory, making the patch can be applied for use in female contraception with the concept of applying the patch once a week.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060121A CU23649B7 (en) | 2006-06-09 | 2006-06-09 | TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060121A CU23649B7 (en) | 2006-06-09 | 2006-06-09 | TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20060121A7 true CU20060121A7 (en) | 2008-06-30 |
| CU23649B7 CU23649B7 (en) | 2011-04-26 |
Family
ID=44280800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20060121A CU23649B7 (en) | 2006-06-09 | 2006-06-09 | TRANSDERMAL ADMINISTRATION HORMONES THAT DO NOT NEED PENETRATION POTENTIATORS |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU23649B7 (en) |
-
2006
- 2006-06-09 CU CU20060121A patent/CU23649B7/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CU23649B7 (en) | 2011-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |