CU20080126A7 - PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH - Google Patents
PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTHInfo
- Publication number
- CU20080126A7 CU20080126A7 CU20080126A CU20080126A CU20080126A7 CU 20080126 A7 CU20080126 A7 CU 20080126A7 CU 20080126 A CU20080126 A CU 20080126A CU 20080126 A CU20080126 A CU 20080126A CU 20080126 A7 CU20080126 A7 CU 20080126A7
- Authority
- CU
- Cuba
- Prior art keywords
- treatment
- cellular growth
- abnormal cellular
- pirimidine derivatives
- derivatives
- Prior art date
Links
- 230000002159 abnormal effect Effects 0.000 title abstract 3
- 230000010261 cell growth Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un compuesto de fórmula I o una sal farmacéuticamente aceptable del mismo,en la que AR es un grupo de fórmula y R1, R2, R13 , A, K, M,L,L1, L2, W, X, Z, Z2, Y1, Y2, ,Z1,Z2, M,Q,W,X , mp,y q son como se definen en este documento. Dichos derivados de pirimidina son útiles en el tratamiento del crecimiento celular anormal, tal como cáncer, en mamíferos.. Esta invención se refiere a un procedimiento de uso de dichos compuestos en el trataminto del crecimiento celular anormal en mamíferos, especialmente seres humanos, y a composiciones farmacéuticas que contienen dichos compuestos.The present invention relates to a compound of formula I or a pharmaceutically acceptable salt thereof, wherein AR is a group of formula and R1, R2, R13, A, K, M, L, L1, L2, W, X , Z, Z2, Y1, Y2,, Z1, Z2, M, Q, W, X, mp, and q are as defined in this document. Said pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention relates to a method of using said compounds in the treatment of abnormal cell growth in mammals, especially humans, and to compositions. pharmaceuticals containing said compounds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20080126A CU20080126A7 (en) | 2008-06-23 | 2008-06-23 | PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20080126A CU20080126A7 (en) | 2008-06-23 | 2008-06-23 | PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20080126A7 true CU20080126A7 (en) | 2010-02-23 |
Family
ID=44280868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20080126A CU20080126A7 (en) | 2008-06-23 | 2008-06-23 | PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU20080126A7 (en) |
-
2008
- 2008-06-23 CU CU20080126A patent/CU20080126A7/en unknown
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