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Application filed by Richter Gedeon NyrtfiledCriticalRichter Gedeon Nyrt
Priority to CU20090190ApriorityCriticalpatent/CU20090190A7/en
Publication of CU20090190A7publicationCriticalpatent/CU20090190A7/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención se refiere a sales novedosas monohidrocloruro, dihidrocloruro, monohidrobromuro, maleato y metanosulfonato de trans 4-{2-[4/(2,3-diclorofenil)-piperazin-1-il]-etil}-N,N-dimetilcarbamoil-ciclohexilamina y/o sus hidratos y/o solvatos. Además, la invención se refiere al proceso de preparación de sales y sus hidratos y/o solvatos, a su uso en el tratamiento y/o prevención de trastornos que requieren la modulación de receptores de dopamina y a composiciones farmacéuticas que la contienen.The present invention relates to novel salts monohydrochloride, dihydrochloride, monohydrobromide, maleate and trans 4- {2- [4 / (2,3-dichlorophenyl) -piperazin-1-yl] -ethyl} -N, N-dimethylcarbamoyl methanesulfonate -cyclohexylamine and / or its hydrates and / or solvates. In addition, the invention relates to the process of preparing salts and their hydrates and / or solvates, their use in the treatment and / or prevention of disorders that require the modulation of dopamine receptors and pharmaceutical compositions containing it.
CU20090190A2009-11-102009-11-10
NOVELED SALTS OF PIPERAZINE AS ANTAGONISTS D3 / D2
CU20090190A7
(en)
TRANS-4- {2- [4- (2, 3-DICHLOROPHENYL) -PIPERAZIN-1-IL] -ETHYL} -N, N-DIMETHYLCARBAMOYL-CYCLOHEXYLAMINE FOR THE TREATMENT OF NEGATIVE SYMPTOMS OF SCHIZOPHRENIA.
Compounds derived from alkyl-piperazino-phenyl 4 (3h) one; Pharmaceutical composition and its use for the treatment of disorders associated with serotonergic receptors 5-ht1a and 5-ht2a, such as depression, anxiety, and sleep disorders.
3-(4-bromobenzoyl)-4-hydroxy-2-{2-[2-pyrimidyl)piperazin-1-yl]-2-oxoethyl}-2H-1,2-benzothiazine 1,1-dioxide with anti-inflammatory and analgesic activity and method for producing it
3-benzyl)-4-hydroxy-2-{2-[4-methoxyphenyl)piperazin-1-yl]2-oxoethyl}-2H-1,2-benzothiazine 1,1-dioxide with anti-inflammatory and analgesic activity and method for producing it