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Application filed by Pfizer Prod IncfiledCriticalPfizer Prod Inc
Priority to CU20100017ApriorityCriticalpatent/CU20100017A7/en
Publication of CU20100017A7publicationCriticalpatent/CU20100017A7/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La invención proporciona compuestos de fórmula (1) (ESPACIO PARA LA FÓRMULA) y la sal farmacéuticamente aceptable de los mismos, en el que R1, R2, R3, R4, R5a, R5b, R5c, R5d, Q, A, Z y R7 son como se ha descrito en este documento; composiciones de los mismos, y usos de los mismos.The invention provides compounds of formula (1) (SPACE FOR FORMULA) and the pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5a, R5b, R5c, R5d, Q, A, Z and R7 they are as described in this document; compositions thereof, and uses thereof.
Compounds derived from 5-alkynyl-pyrimidines, kinase inhibitors; pharmaceutical compositions containing them; and its use for the treatment and / or prevention of cancer, infections, inflammatory and autoimmune diseases.