CU20100036A7 - IMPROVEMENTS IN ORGANIC COMPOUNDS OR RELATED TO THE SAME - Google Patents
IMPROVEMENTS IN ORGANIC COMPOUNDS OR RELATED TO THE SAMEInfo
- Publication number
- CU20100036A7 CU20100036A7 CU20100036A CU20100036A CU20100036A7 CU 20100036 A7 CU20100036 A7 CU 20100036A7 CU 20100036 A CU20100036 A CU 20100036A CU 20100036 A CU20100036 A CU 20100036A CU 20100036 A7 CU20100036 A7 CU 20100036A7
- Authority
- CU
- Cuba
- Prior art keywords
- lactamide
- compound
- formula
- morpholinyl
- hydroxyethyl
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- -1 1- (hydroxyethyl) piperidinyl lactamide Chemical compound 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002757 morpholinyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical compound C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
- UFNOUKDBUJZYDE-UHFFFAOYSA-N 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1CC(O)(C=1C=CC(Cl)=CC=1)C(C)C1CC1 UFNOUKDBUJZYDE-UHFFFAOYSA-N 0.000 abstract 1
- WIMBMTLEAYHHAH-UHFFFAOYSA-N 2-ethyl-2-hydroxypentanamide Chemical compound CCCC(O)(CC)C(N)=O WIMBMTLEAYHHAH-UHFFFAOYSA-N 0.000 abstract 1
- BHPSBYAVFSKVKY-UHFFFAOYSA-N 2-hydroxy-2-methylbutanamide Chemical compound CCC(C)(O)C(N)=O BHPSBYAVFSKVKY-UHFFFAOYSA-N 0.000 abstract 1
- YEBLAXBYYVCOLT-UHFFFAOYSA-N 2-hydroxy-n,n-dimethylpropanamide Chemical compound CC(O)C(=O)N(C)C YEBLAXBYYVCOLT-UHFFFAOYSA-N 0.000 abstract 1
- JRRGKOBGBAFIJS-UHFFFAOYSA-N 2-hydroxy-n-(2-methylpropyl)propanamide Chemical compound CC(C)CNC(=O)C(C)O JRRGKOBGBAFIJS-UHFFFAOYSA-N 0.000 abstract 1
- KTLCZZZKLTTYSE-UHFFFAOYSA-N 2-hydroxy-n-methyl-n-propylpropanamide Chemical compound CCCN(C)C(=O)C(C)O KTLCZZZKLTTYSE-UHFFFAOYSA-N 0.000 abstract 1
- VYRFYCXXJNFPBJ-UHFFFAOYSA-N 2-hydroxy-n-pentan-3-ylpropanamide Chemical compound CCC(CC)NC(=O)C(C)O VYRFYCXXJNFPBJ-UHFFFAOYSA-N 0.000 abstract 1
- PLSSYQFNLOOTSH-UHFFFAOYSA-N 2-hydroxy-n-propan-2-ylpropanamide Chemical compound CC(C)NC(=O)C(C)O PLSSYQFNLOOTSH-UHFFFAOYSA-N 0.000 abstract 1
- RLOHOBNEYHBZID-UHFFFAOYSA-N 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid Chemical compound CN1C=C(C(O)=O)C(C(F)F)=N1 RLOHOBNEYHBZID-UHFFFAOYSA-N 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 239000005757 Cyproconazole Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003725 azepanyl group Chemical group 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- BTYDMJBYSQYUQN-UHFFFAOYSA-N n-(3-butoxypropyl)-2-hydroxypropanamide Chemical compound CCCCOCCCNC(=O)C(C)O BTYDMJBYSQYUQN-UHFFFAOYSA-N 0.000 abstract 1
- KIDDFCOSIQIGDC-UHFFFAOYSA-N n-benzyl-2-hydroxy-n-(2-hydroxyethyl)propanamide Chemical compound CC(O)C(=O)N(CCO)CC1=CC=CC=C1 KIDDFCOSIQIGDC-UHFFFAOYSA-N 0.000 abstract 1
- DOYUGTNFQGMDGM-UHFFFAOYSA-N n-ethyl-2-hydroxy-n-(2-hydroxyethyl)propanamide Chemical compound OCCN(CC)C(=O)C(C)O DOYUGTNFQGMDGM-UHFFFAOYSA-N 0.000 abstract 1
- PWHWWMHNXSWQLD-UHFFFAOYSA-N n-ethyl-2-hydroxypropanamide Chemical compound CCNC(=O)C(C)O PWHWWMHNXSWQLD-UHFFFAOYSA-N 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Una composición que comprende un compuesto de fórmula (I) CH3CH(OH)C(=O)NR1R2 (I) donde R1 y R2 son cada uno independientemente hidrógeno; o alquilo C1-6, alquenilo C2-6 o cicloalquilo C3-6, cada uno de los cuales está opcionalmente sustituido con hasta tres sustituyentes seleccionados independientemente entre fenilo, hidroxi, alcoxi C1-5, morfolinilo y NR3R4 donde R3 y R4 son cada uno independientemente alquilo C1-3; o fenilo opcionalmente sustituido con hasta tres sustituyentes seleccionados independientemente entre alquilo C1-3; o R1 y R2 junto con el átomo de nitrógeno al cual están unidos forman un anillo morfolinilo, pirrolidinilo, piperidinilo o azepanilo, cada uno de los cuales está opcionalmente sustituido con hasta tres sustituyentes seleccionados independientemente entre alquilo C1-3; y por lo menos un compuesto biológicamente activo, el cual comprende por lo menos un anillo aromático de cinco y/o seis miembros donde el anillo contiene por lo menos un nitrógeno como un miembro del anillo, con las siguientes condiciones: (i) que la composición no contenga ciproconazol cuando el compuesto de fórmula 1 se selecciona del grupo formado por N-butoxipropil-lactamida; 1-(hidroxietil)piperidinil-lactamida; N-metil-N-propil-lactamida; N-(1-etilpropil)-lactamida; N,N-dimetil-lactamida; N-1,4-dimetilpentil-lactamida; N-(2-hidroxietil)-N-bencil-lactamida; N-Morfolinil-lactamida; N-metil-N-butil-lactamida; N-Isobutil-lactamida; N-Alil-lactamida; N-Etil-lactamida; N-Etil-N-(2-hidroxietil)-lactamida; y N-isopropil-lactamida; y (ii) que el compuesto biológicamente activo no sea ácido nicotínico cuando el compuesto de fórmula 1 es dietil-lactamida. Dichas composiciones pueden ser, o pueden estar compuestas por, concentrados en emulsión, particularmente en el caso de que el compuesto de fórmula 1 sea dimetil-lactamida y el compuesto biológicamente activo sea el fungicida (9-isopropil-1,2,3,4-tetrahidro-1,4-metano-naftalen-5-il)-amida del ácido 3-difluormetil-1-metil-1H-pirazol-4-carboxílico que se muestra en la figura 2.A composition comprising a compound of formula (I) CH3CH (OH) C (= O) NR1R2 (I) wherein R1 and R2 are each independently hydrogen; or C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl, each of which is optionally substituted with up to three substituents independently selected from phenyl, hydroxy, C1-5 alkoxy, morpholinyl and NR3R4 where R3 and R4 are each independently C1-3 alkyl; or phenyl optionally substituted with up to three substituents independently selected from C1-3 alkyl; or R1 and R2 together with the nitrogen atom to which they are attached form a morpholinyl, pyrrolidinyl, piperidinyl or azepanyl ring, each of which is optionally substituted with up to three substituents independently selected from C1-3alkyl; and at least one biologically active compound, which comprises at least one aromatic ring of five and / or six members where the ring contains at least one nitrogen as a member of the ring, with the following conditions: (i) that the composition does not contain cyproconazole when the compound of formula 1 is selected from the group consisting of N-butoxypropyl-lactamide; 1- (hydroxyethyl) piperidinyl lactamide; N-methyl-N-propyl-lactamide; N- (1-ethylpropyl) -lactamide; N, N-dimethyl-lactamide; N-1,4-dimethylpentyl-lactamide; N- (2-hydroxyethyl) -N-benzyl-lactamide; N-Morpholinyl Lactamide; N-methyl-N-butyl lactamide; N-Isobutyl-lactamide; N-Alyl-lactamide; N-Ethyl-lactamide; N-Ethyl-N- (2-hydroxyethyl) -lactamide; and N-isopropyl-lactamide; and (ii) that the biologically active compound is not nicotinic acid when the compound of formula 1 is diethyl-lactamide. Such compositions may be, or may be composed of, emulsion concentrates, particularly in the case where the compound of formula 1 is dimethyl-lactamide and the biologically active compound is the fungicide (9-isopropyl-1,2,3,4 3-Difluoromethyl-1-methyl-1 H -pyrazol-4-carboxylic acid tetrahydro-1,4-methane-naphthalen-5-yl) -amide shown in Figure 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100036A CU20100036A7 (en) | 2010-02-22 | 2010-02-22 | IMPROVEMENTS IN ORGANIC COMPOUNDS OR RELATED TO THE SAME |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100036A CU20100036A7 (en) | 2010-02-22 | 2010-02-22 | IMPROVEMENTS IN ORGANIC COMPOUNDS OR RELATED TO THE SAME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20100036A7 true CU20100036A7 (en) | 2011-10-05 |
Family
ID=45000064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20100036A CU20100036A7 (en) | 2010-02-22 | 2010-02-22 | IMPROVEMENTS IN ORGANIC COMPOUNDS OR RELATED TO THE SAME |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU20100036A7 (en) |
-
2010
- 2010-02-22 CU CU20100036A patent/CU20100036A7/en unknown
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