CU20100083A7 - Tolerogenos adyuvados como vacuna de malaria - Google Patents

Tolerogenos adyuvados como vacuna de malaria

Info

Publication number
CU20100083A7
CU20100083A7 CU20100083A CU20100083A CU20100083A7 CU 20100083 A7 CU20100083 A7 CU 20100083A7 CU 20100083 A CU20100083 A CU 20100083A CU 20100083 A CU20100083 A CU 20100083A CU 20100083 A7 CU20100083 A7 CU 20100083A7
Authority
CU
Cuba
Prior art keywords
tolerogens
malaria
vaccine
adjused
induce
Prior art date
Application number
CU20100083A
Other languages
English (en)
Inventor
Alvarez Belkis Romeu
Gonzalez Julio Antonio Balboa
Aznar Elizabeth Gonzalez
Gonzalez Miriam De San Juan Bosco Lastre
Vignier Caridad Zayas
Perez Maribel Cuello
Blanco Osmir Cabrera
Martin Oliver German Perez
Original Assignee
Inst Finlay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Finlay filed Critical Inst Finlay
Priority to CU20100083A priority Critical patent/CU20100083A7/es
Priority to ARP110101532A priority patent/AR081008A1/es
Priority to EP11777295.4A priority patent/EP2548572A4/en
Priority to PCT/CU2011/000002 priority patent/WO2011137876A2/es
Priority to RU2012151576/10A priority patent/RU2012151576A/ru
Publication of CU20100083A7 publication Critical patent/CU20100083A7/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con el campo de las composiciones vacunales para el tratamiento efectivo o preventivo de infecciones de transmisión vertical, particularmente la Malaria y preferiblemente la humana causada por Plasmodium falciparum. El objetivo técnico que se persigue es usar los tolerógenos transferidos tempranamente de la madre al feto/recién nacido y formularlos con potentes adyuvantes inductores de respuestas Th1 y T citotóxica para su uso en vacunas profilácticas o terapéuticas contra las infecciones de transmisión vertical y particularmente la Malaria. El empleo de estas formulaciones por vía parenteral o mucosal o ambas a la vez en edades tempranas, revierte la tolerancia inducida por la transferencia de tolerógenos y con ello inducir respuestas protectivas.
CU20100083A 2010-05-05 2010-05-05 Tolerogenos adyuvados como vacuna de malaria CU20100083A7 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CU20100083A CU20100083A7 (es) 2010-05-05 2010-05-05 Tolerogenos adyuvados como vacuna de malaria
ARP110101532A AR081008A1 (es) 2010-05-05 2011-05-04 Tolerogenos adyuvados como vacuna de malaria
EP11777295.4A EP2548572A4 (en) 2010-05-05 2011-05-05 TOLEROGENES ADJUVATED AS VACCINES AGAINST MALARIA
PCT/CU2011/000002 WO2011137876A2 (es) 2010-05-05 2011-05-05 Tolerogenos adyuvados como vacuna de malaria
RU2012151576/10A RU2012151576A (ru) 2010-05-05 2011-05-05 Адъювантированные толерогены в качестве вакцины от малярии

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20100083A CU20100083A7 (es) 2010-05-05 2010-05-05 Tolerogenos adyuvados como vacuna de malaria

Publications (1)

Publication Number Publication Date
CU20100083A7 true CU20100083A7 (es) 2012-06-21

Family

ID=44904160

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20100083A CU20100083A7 (es) 2010-05-05 2010-05-05 Tolerogenos adyuvados como vacuna de malaria

Country Status (5)

Country Link
EP (1) EP2548572A4 (es)
AR (1) AR081008A1 (es)
CU (1) CU20100083A7 (es)
RU (1) RU2012151576A (es)
WO (1) WO2011137876A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200022388A (ko) 2017-06-23 2020-03-03 바르셀로나 인스티튜트 포 글로벌 헬스 임신에 대한 시스템, 방법, 장치 및 진단학적 시험
CN112956668A (zh) * 2021-03-11 2021-06-15 浙江省农业科学院 一种超声辅助生物酶法制备破壁蜂花粉的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01125328A (ja) 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
CU22983A1 (es) 2002-05-08 2004-09-09 Inst Finlay Composición vacunal contra las alergias y método para su obtención y empleo en el tratamiento de las mismas
CU23313A1 (es) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
CN1886156A (zh) * 2003-09-30 2006-12-27 特莱索恩儿童健康研究院 免疫治疗方法
CU23420A1 (es) 2003-12-30 2009-09-08 Univ De Cambridge Proteoliposomas y sus derivados como adyuvantes inductores de respuesta citotóxica y las formulaciones resultantes
US8026354B2 (en) * 2005-11-23 2011-09-27 Institut Pasteur Recombinant plasmodium falciparum merozoite surface proteins 4 and 5 and their use
CU20080215A7 (es) 2008-11-19 2012-06-21 Inst Finlay Vacunas unitemporales

Also Published As

Publication number Publication date
RU2012151576A (ru) 2014-06-10
WO2011137876A3 (es) 2012-01-05
EP2548572A4 (en) 2013-12-11
EP2548572A2 (en) 2013-01-23
WO2011137876A2 (es) 2011-11-10
AR081008A1 (es) 2012-05-30

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