CU20100174A7 -
HETEROCYCLIC OR HIPERBYCLIC BICYCLIC DERIVATIVES LINKED PYRAZOL [1,5-A] PYRIMIDINES, PROCEDURE FOR PREPARATION AND USES OF THE SAME
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HETEROCYCLIC OR HIPERBYCLIC BICYCLIC DERIVATIVES LINKED PYRAZOL [1,5-A] PYRIMIDINES, PROCEDURE FOR PREPARATION AND USES OF THE SAME
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CU20100174A7
CU20100174A7CU20100174ACU20100174ACU20100174A7CU 20100174 A7CU20100174 A7CU 20100174A7CU 20100174 ACU20100174 ACU 20100174ACU 20100174 ACU20100174 ACU 20100174ACU 20100174 A7CU20100174 A7CU 20100174A7
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Priority to CU20100174ApriorityCriticalpatent/CU20100174A7/en
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Se describen compuestos de fórmula A: ESPACIO PARA LA FÓRMULA y sales farmacéuticamente aceptables de los mismos, que inhiben selectivamente la actividad Raf quinasa y son útiles para tratar trastornos mediados por Raf quinasas.Compounds of formula A are described: SPACE FOR FORMULA and pharmaceutically acceptable salts thereof, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.
CU20100174A2010-08-262010-08-26
HETEROCYCLIC OR HIPERBYCLIC BICYCLIC DERIVATIVES LINKED PYRAZOL [1,5-A] PYRIMIDINES, PROCEDURE FOR PREPARATION AND USES OF THE SAME
CU20100174A7
(en)
Substituted pyrazolo [1,5-a] pyridine compounds, inhibitors of the tropomyosin kinase receptor (trk); pharmaceutical composition that includes them; method of inhibiting the tropomyosin kinase receptor a (trka); and method of treatment or prevention of pain, cancer, restenosis and atherosclerosis, among other diseases.