CU20120067A7 - HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS - Google Patents

HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS

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Publication number
CU20120067A7
CU20120067A7 CU20120067A CU20120067A CU20120067A7 CU 20120067 A7 CU20120067 A7 CU 20120067A7 CU 20120067 A CU20120067 A CU 20120067A CU 20120067 A CU20120067 A CU 20120067A CU 20120067 A7 CU20120067 A7 CU 20120067A7
Authority
CU
Cuba
Prior art keywords
mek inhibitors
sulfamide derivatives
heterocyclic
heterocyclic sulfamide
compounds
Prior art date
Application number
CU20120067A
Other languages
Spanish (es)
Inventor
Chetan Pandit
Dinesh Chikkanna
Henrik Moebitz
Mark G Bock
Clive Mccarthy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to CU20120067A priority Critical patent/CU20120067A7/en
Publication of CU20120067A7 publication Critical patent/CU20120067A7/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a los comp0uestos de la fórmula (IA) ESPACIO PARA FÓRMULA en donde R^1a, R^1b, X, R^2a, R^2b, WW, R^3, R^4, y R^5 son como se definen en la presente, así como a las sales farmacéuticamente aceptables de los mismos. Se han demostrado que los compuestos actúan como inhibidores de MEK, lo cual puede ser útil en el tratamiento de enfermedades hiperproliferativas, como cáncer e inflamacion.The present invention relates to the compounds of formula (IA) SPACE FOR FORMULA wherein R ^ 1a, R ^ 1b, X, R ^ 2a, R ^ 2b, WW, R ^ 3, R ^ 4, and R ^ 5 are as defined herein, as well as pharmaceutically acceptable salts thereof. The compounds have been shown to act as MEK inhibitors, which may be useful in the treatment of hyperproliferative diseases, such as cancer and inflammation.

CU20120067A 2012-04-25 2012-04-25 HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS CU20120067A7 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CU20120067A CU20120067A7 (en) 2012-04-25 2012-04-25 HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20120067A CU20120067A7 (en) 2012-04-25 2012-04-25 HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS

Publications (1)

Publication Number Publication Date
CU20120067A7 true CU20120067A7 (en) 2012-06-29

Family

ID=46516978

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20120067A CU20120067A7 (en) 2012-04-25 2012-04-25 HETEROCYCLIC SULFAMIDE DERIVATIVES AND ITS USE AS MEK INHIBITORS

Country Status (1)

Country Link
CU (1) CU20120067A7 (en)

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