CU20130127A7 - MODULATION OF SIGNAL TRANSDUCER EXPRESSION AND TRANSCRIPTION ACTIVATOR 3 (STAT3) - Google Patents
MODULATION OF SIGNAL TRANSDUCER EXPRESSION AND TRANSCRIPTION ACTIVATOR 3 (STAT3)Info
- Publication number
- CU20130127A7 CU20130127A7 CU2013000127A CU20130127A CU20130127A7 CU 20130127 A7 CU20130127 A7 CU 20130127A7 CU 2013000127 A CU2013000127 A CU 2013000127A CU 20130127 A CU20130127 A CU 20130127A CU 20130127 A7 CU20130127 A7 CU 20130127A7
- Authority
- CU
- Cuba
- Prior art keywords
- expression
- stat3
- modulation
- signal transducer
- transcription activator
- Prior art date
Links
- 239000012190 activator Substances 0.000 title 1
- 230000035897 transcription Effects 0.000 title 1
- 238000013518 transcription Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004495 STAT3 Transcription Factor Human genes 0.000 abstract 1
- 108010017324 STAT3 Transcription Factor Proteins 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se describen en la presente compuestos antisentido y métodos para disminuir la expresión de ARNm y proteínas STAT3. Dichos métodos, compuestos y composiciones son de utilidad para tratar, prevenir o aliviar enfermedades hiperproliferativas.Antisense compounds and methods for decreasing the expression of mRNA and STAT3 proteins are described herein. Such methods, compounds and compositions are useful for treating, preventing or alleviating hyperproliferative diseases.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161471045P | 2011-04-01 | 2011-04-01 | |
| US201161558316P | 2011-11-10 | 2011-11-10 | |
| PCT/US2012/031642 WO2012135736A2 (en) | 2011-04-01 | 2012-03-30 | Modulation of signal transducer and activator of transcription 3 (stat3) expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20130127A7 true CU20130127A7 (en) | 2014-01-29 |
| CU24088B1 CU24088B1 (en) | 2015-03-30 |
Family
ID=52394793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2013000127A CU24088B1 (en) | 2011-04-01 | 2012-03-30 | SIMPLE CHAIN OLIGONUCLEOTIDE INHIBITOR OF THE STAT3 PROTEIN |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU24088B1 (en) |
-
2012
- 2012-03-30 CU CU2013000127A patent/CU24088B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CU24088B1 (en) | 2015-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP13012909A (en) | MODULATION OF SIGNAL TRANSDUCER EXPRESSION AND TRANSCRIPTION ACTIVATOR 3 (STAT3) | |
| CY1122480T1 (en) | VARDOXOLONE METHYL FOR THE TREATMENT OF OBESITY | |
| AU2018260809A1 (en) | Compounds and uses thereof for the modulation of hemoglobin | |
| AU2018260808A1 (en) | Compounds and uses thereof for the modulation of hemoglobin | |
| MX2016014140A (en) | Compositions and methods for modulating pkk expression. | |
| MX2018010427A (en) | Solid forms of a thienopyrimidinedione acc inhibitor and methods for production thereof. | |
| TN2013000378A1 (en) | Anti - sclerostin antibody crystals and formulations thereof | |
| EP4036240A3 (en) | Transduction buffer | |
| EP3715457A3 (en) | Modulation of prekallikrein (pkk) expression | |
| MX2021001169A (en) | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino}acetic acid, compositions, and uses thereof. | |
| EP3329919A8 (en) | Acc inhibitors and uses thereof | |
| MX2015015421A (en) | Acc inhibitors and uses thereof. | |
| EA201270100A1 (en) | Pyrimidinones as PI3K inhibitors | |
| MX2015015417A (en) | Acc inhibitors and uses thereof. | |
| BR112013014119A8 (en) | NEW MODULATORS AND METHODS OF USE | |
| PH12014500904B1 (en) | Antibody formulations and methods | |
| EA201170160A1 (en) | NEW INHIBITORS OF PROLIFERATION AND ACTIVATION OF THE SIGNAL TRANSFER AND ACTIVATOR TRANSCRIPTION (STATS) | |
| EA201592238A1 (en) | PI3K PROTEINKINASE INHIBITORS, IN PARTICULAR PI3K DELTA AND / OR GAMMA INHIBITORS | |
| AU2014230812A8 (en) | Process for making benzoxazepin compounds | |
| UY34070A (en) | METHOD AND COMPOSITION FOR SEED TREATMENT. | |
| UY34543A (en) | DERIVATIVES OF SULFONYLAMINOPIRROLIDINONE, ITS PREPARATION AND THERAPEUTIC APPLICATION. | |
| PH12015502577B1 (en) | Modulation of heparin-binding epidermal growth factor activity for tympanic membrane healing | |
| MX377276B (en) | (S)-1-PHENYL-2-(PYRIDIN-2-YL) ETHANAMINE (NMDA) ANTAGONIST PRODRUGS. | |
| CU20130127A7 (en) | MODULATION OF SIGNAL TRANSDUCER EXPRESSION AND TRANSCRIPTION ACTIVATOR 3 (STAT3) | |
| TN2013000055A1 (en) | Heteroaryls and uses thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |