CU20140033A7 - PIRROLOPIRIMIDINE AND PURINE DERIVATIVES - Google Patents
PIRROLOPIRIMIDINE AND PURINE DERIVATIVESInfo
- Publication number
- CU20140033A7 CU20140033A7 CU2014000033A CU20140033A CU20140033A7 CU 20140033 A7 CU20140033 A7 CU 20140033A7 CU 2014000033 A CU2014000033 A CU 2014000033A CU 20140033 A CU20140033 A CU 20140033A CU 20140033 A7 CU20140033 A7 CU 20140033A7
- Authority
- CU
- Cuba
- Prior art keywords
- compounds
- purine derivatives
- pirrolopirimidine
- mammals
- cell growth
- Prior art date
Links
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title abstract 2
- 150000003212 purines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 2
- 230000010261 cell growth Effects 0.000 abstract 2
- KDOPAZIWBAHVJB-UHFFFAOYSA-N 5h-pyrrolo[3,2-d]pyrimidine Chemical compound C1=NC=C2NC=CC2=N1 KDOPAZIWBAHVJB-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a compuestos de la Fórmula ( I) O sales de estos aceptables desde el punto de vista farmacéutico, en donde Q, T, V, W, X, Y, Z, el anillo A, R^1, R^2, R^3, R^4, R^5, R^6, R^7, R^8, R^9, R^10, R^11, R^12, R^13, R^14, R^15, R^16, R^17 y m se definen en la presente. Los derivados de pirrolopirimidina y purina novedosos son útiles para tratar el crecimiento celular anormal, tal como cáncer, en mamíferos. Otras formas de realización se refieren a composiciones farmacéuticas que contienen los compuestos y a métodos para usar los compuestos y las composiciones en el tratamiento del crecimiento celular anormal en mamíferos.The present invention relates to compounds of the Formula (I) OR pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R ^ 1, R ^ 2, R ^ 3, R ^ 4, R ^ 5, R ^ 6, R ^ 7, R ^ 8, R ^ 9, R ^ 10, R ^ 11, R ^ 12, R ^ 13, R ^ 14 , R ^ 15, R ^ 16, R ^ 17 and m are defined herein. The novel pyrrolopyrimidine and purine derivatives are useful for treating abnormal cell growth, such as cancer, in mammals. Other embodiments relate to pharmaceutical compositions containing the compounds and to methods for using the compounds and compositions in the treatment of abnormal cell growth in mammals.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261639639P | 2012-04-27 | 2012-04-27 | |
| PCT/IB2012/054702 WO2013042006A1 (en) | 2011-09-22 | 2012-09-10 | Pyrrolopyrimidine and purine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20140033A7 true CU20140033A7 (en) | 2014-05-27 |
Family
ID=52394769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2014000033A CU20140033A7 (en) | 2012-04-27 | 2014-03-20 | PIRROLOPIRIMIDINE AND PURINE DERIVATIVES |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU20140033A7 (en) |
-
2014
- 2014-03-20 CU CU2014000033A patent/CU20140033A7/en unknown
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