CU20160002A7 - PARACETAMOL / CELECOXIB SYNERGISTIC COMBINATION FOR THE INFLAMMATORY PAIN TREATMENT - Google Patents

PARACETAMOL / CELECOXIB SYNERGISTIC COMBINATION FOR THE INFLAMMATORY PAIN TREATMENT

Info

Publication number
CU20160002A7
CU20160002A7 CUP2016000002A CU20160002A CU20160002A7 CU 20160002 A7 CU20160002 A7 CU 20160002A7 CU P2016000002 A CUP2016000002 A CU P2016000002A CU 20160002 A CU20160002 A CU 20160002A CU 20160002 A7 CU20160002 A7 CU 20160002A7
Authority
CU
Cuba
Prior art keywords
paracetamol
celecoxib
inflammatory pain
synergistic combination
pain treatment
Prior art date
Application number
CUP2016000002A
Other languages
Spanish (es)
Other versions
CU24440B1 (en
Inventor
Medellin Jorge Fernando Cantú
Original Assignee
More Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52279400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20160002(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by More Pharma Corp filed Critical More Pharma Corp
Publication of CU20160002A7 publication Critical patent/CU20160002A7/en
Publication of CU24440B1 publication Critical patent/CU24440B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe y reclama una combinación de paracetamol y celecoxib que en cantidades específicas generan una potenciación analgésica contra el dolor de tipo inflamatorio. Específicamente, la invención se refiere una combinación sinergística de entre 375 a 500 mg de paracetamol y de entre 50 a 100 mg de celecoxib útil para el tratamiento de dolor inflamatorio en animales y seres humanos, así como el uso de dichos principios activos en las cantidades indicadas en la preparación de combinaciones farmacéuticas sinérgicas.A combination of paracetamol and celecoxib is described and claimed that in specific amounts generate an analgesic potentiation against inflammatory pain. Specifically, the invention relates to a synergistic combination of between 375 to 500 mg of paracetamol and between 50 to 100 mg of celecoxib useful for the treatment of inflammatory pain in animals and humans, as well as the use of said active ingredients in the amounts indicated in the preparation of synergistic pharmaceutical combinations.

CU2016000002A 2013-07-11 2014-07-11 PHARMACEUTICAL COMPOSITION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN CU24440B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2013/055710 WO2015004505A1 (en) 2013-07-11 2013-07-11 Synergistic combination of paracetamol/celecoxib for the treatment of inflammatory pain
PCT/IB2014/063019 WO2015004634A2 (en) 2013-07-11 2014-07-11 Synergistic combination of paracetamol/celecoxib for the treatment of inflammatory pain

Publications (2)

Publication Number Publication Date
CU20160002A7 true CU20160002A7 (en) 2016-06-29
CU24440B1 CU24440B1 (en) 2019-09-04

Family

ID=52279400

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2016000002A CU24440B1 (en) 2013-07-11 2014-07-11 PHARMACEUTICAL COMPOSITION OF PARACETAMOL / CELECOXIB FOR THE TREATMENT OF INFLAMMATORY PAIN

Country Status (8)

Country Link
CL (1) CL2015003211A1 (en)
CR (1) CR20160021A (en)
CU (1) CU24440B1 (en)
DO (1) DOP2016000008A (en)
EC (1) ECSP16005679A (en)
MX (1) MX366118B (en)
PE (2) PE20160239A1 (en)
WO (2) WO2015004505A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11147780B2 (en) * 2020-02-24 2021-10-19 Algia Pharma, Llc Multidrug pain management package
MX2023011799A (en) 2023-10-05 2025-05-02 Laboratorios Silanes S A De C V Multi-active tablet in the treatment and control of severe chronic pain and method of preparation
MX2023011800A (en) * 2023-10-05 2025-05-02 Laboratorios Silanes S A De C V Improved stability celecoxib-acetaminophen combination and process for its preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535500A (en) * 2002-02-19 2006-09-29 Adcock Ingram Ltd Pharmaceutical combinations of COX-2 inhibitors i.e. meloxicam, opiates i.e. codeine and centrally acting cox inhibitors i.e. paracetamol
GB0423103D0 (en) * 2004-10-19 2004-11-17 Boots Healthcare Int Ltd Therapeutic agents

Also Published As

Publication number Publication date
PE20160239A1 (en) 2016-05-13
WO2015004505A1 (en) 2015-01-15
MX366118B (en) 2019-06-27
WO2015004634A3 (en) 2015-04-09
CL2015003211A1 (en) 2016-04-29
MX2015013911A (en) 2015-12-08
ECSP16005679A (en) 2017-08-31
PE20170305A1 (en) 2017-04-21
DOP2016000008A (en) 2016-03-15
CR20160021A (en) 2016-04-08
CU24440B1 (en) 2019-09-04
WO2015004634A2 (en) 2015-01-15

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