CU20160188A7 - Compuestos de indazole substituidos como inhibidores de irak4 - Google Patents

Compuestos de indazole substituidos como inhibidores de irak4

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Publication number
CU20160188A7
CU20160188A7 CUP2016000188A CU20160188A CU20160188A7 CU 20160188 A7 CU20160188 A7 CU 20160188A7 CU P2016000188 A CUP2016000188 A CU P2016000188A CU 20160188 A CU20160188 A CU 20160188A CU 20160188 A7 CU20160188 A7 CU 20160188A7
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CU
Cuba
Prior art keywords
compounds substituted
indazole compounds
irak4 inhibitors
irak4
inhibitors
Prior art date
Application number
CUP2016000188A
Other languages
English (en)
Inventor
Venkateshwar Rao Gummadi
Susanta Samajdar
Original Assignee
Aurigene Discovery Tech Ltd
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Publication date
Application filed by Aurigene Discovery Tech Ltd filed Critical Aurigene Discovery Tech Ltd
Publication of CU20160188A7 publication Critical patent/CU20160188A7/es

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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Abstract

La presente invención proporciona un compuesto de indazol sustituido de fórmula (I) y sus sales farmacéuticamente aceptables, y su uso para inhibir IRAK4 y/o para el tratamiento de enfermedades o trastornos inducidos por IRAK4.
CUP2016000188A 2014-06-20 2015-06-19 Compuestos de indazole substituidos como inhibidores de irak4 CU20160188A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3017CH2014 2014-06-20
PCT/IB2015/054620 WO2015193846A1 (en) 2014-06-20 2015-06-19 Substituted indazole compounds as irak4 inhibitors

Publications (1)

Publication Number Publication Date
CU20160188A7 true CU20160188A7 (es) 2017-06-05

Family

ID=54934936

Family Applications (1)

Application Number Title Priority Date Filing Date
CUP2016000188A CU20160188A7 (es) 2014-06-20 2015-06-19 Compuestos de indazole substituidos como inhibidores de irak4

Country Status (16)

Country Link
US (1) US20170152263A1 (es)
EP (1) EP3157521A4 (es)
JP (1) JP2017518348A (es)
KR (1) KR20170016500A (es)
CN (1) CN106456609A (es)
AU (1) AU2015275730A1 (es)
BR (1) BR112016029853A2 (es)
CA (1) CA2952188A1 (es)
CU (1) CU20160188A7 (es)
EA (1) EA201692418A1 (es)
HK (1) HK1231411A1 (es)
IL (1) IL249345A0 (es)
MX (1) MX2016017147A (es)
PH (1) PH12016502382A1 (es)
SG (1) SG11201610009XA (es)
WO (1) WO2015193846A1 (es)

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JP2020524691A (ja) 2017-06-21 2020-08-20 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ＩＲＡＫ４調節因子としてのピラゾロ［１，５ａ］ピリミジン誘導体
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