CU20210077A7 - Extractos bacterianos estables como fármacos - Google Patents

Extractos bacterianos estables como fármacos

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Publication number
CU20210077A7
CU20210077A7 CU2021000077A CU20210077A CU20210077A7 CU 20210077 A7 CU20210077 A7 CU 20210077A7 CU 2021000077 A CU2021000077 A CU 2021000077A CU 20210077 A CU20210077 A CU 20210077A CU 20210077 A7 CU20210077 A7 CU 20210077A7
Authority
CU
Cuba
Prior art keywords
drugs
bacterial extracts
stable bacterial
stable
extracts
Prior art date
Application number
CU2021000077A
Other languages
English (en)
Inventor
Jacques Bauer
Christian Pasquali
Original Assignee
Om Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Om Pharma Sa filed Critical Om Pharma Sa
Publication of CU20210077A7 publication Critical patent/CU20210077A7/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/08Reducing the nucleic acid content
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

<p>La presente invención se refiere a preparaciones de extractos bacterianos estables, métodos de preparación de los mismos y formulaciones farmacéuticas que los comprenden.</p>
CU2021000077A 2019-03-14 2020-03-12 Extractos bacterianos estables como fármacos CU20210077A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19162912 2019-03-14
PCT/EP2020/056742 WO2020182970A1 (en) 2019-03-14 2020-03-12 Process for making stable bacterial extracts and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
CU20210077A7 true CU20210077A7 (es) 2022-04-07

Family

ID=65991511

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2021000077A CU20210077A7 (es) 2019-03-14 2020-03-12 Extractos bacterianos estables como fármacos

Country Status (19)

Country Link
US (3) US11801271B2 (es)
EP (3) EP4234026A3 (es)
JP (2) JP2022525177A (es)
KR (1) KR102922470B1 (es)
CN (1) CN113840615A (es)
BR (1) BR112021018006A2 (es)
CA (1) CA3132564A1 (es)
CL (1) CL2021002401A1 (es)
CO (1) CO2021013677A2 (es)
CR (1) CR20210515A (es)
CU (1) CU20210077A7 (es)
IL (1) IL286215B2 (es)
MA (1) MA55291A (es)
MX (1) MX2021010912A (es)
PE (1) PE20212261A1 (es)
PH (1) PH12021552089A1 (es)
SG (1) SG11202109937UA (es)
WO (1) WO2020182970A1 (es)
ZA (1) ZA202106914B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021018086A2 (pt) * 2019-03-14 2021-11-23 Univ Arizona Método de tratamento e/ou prevenção de asma, exacerbações de asma, asma alérgica e/ou condições associadas com microbiota relacionadas a distúrbios respiratórios
TW202304485A (zh) * 2021-04-12 2023-02-01 香港中文大學 用於增強免疫力的方法和組合物
KR20220152156A (ko) * 2021-05-07 2022-11-15 시므라이즈 아게 락토바실러스 종의 신규한 박테리아 발효물
WO2022233441A1 (en) * 2021-05-07 2022-11-10 Symrise Ag Novel bacterial ferment of lactobacillus species
EP4134426A1 (en) * 2021-08-13 2023-02-15 Symrise AG Novel bacterial ferment of lactobacillus species
CN118475359A (zh) * 2021-12-22 2024-08-09 株式会社明治 用于预防继发感染症或用于降低继发感染症发生风险的组合物
KR102763094B1 (ko) * 2022-12-09 2025-02-12 대한민국 혈관 염증 완화에 효과적인 식용 곰팡이 균주의 가수분해 물질의 제조 방법
CN118460405B (zh) * 2024-04-26 2025-03-04 广东悦创生物科技有限公司 一株副干酪乳酪杆菌xy6及其在制备调理肠胃和减肥药品中的应用
CN121427776B (zh) * 2025-12-26 2026-04-10 威凯海思(山东)生物工程有限公司 一株罗伊氏粘液乳杆菌hc1602及其菌剂和应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8007911A (pt) 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
DE3274065D1 (de) 1981-07-08 1986-12-11 Draco Ab Powder inhalator
AU591152B2 (en) 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
CH685498A5 (fr) 1992-02-14 1995-07-31 Om Lab Sa Extrait de macromolécules bactériennes, procédé pour sa préparation et composition pharmaceutique contenant cet extrait.
US5497763A (en) 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
US7171965B2 (en) 2000-02-01 2007-02-06 Valois S.A.S. Breath actuated dry powder inhaler and tape dose strip
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
DK1817423T3 (en) * 2004-11-30 2015-01-26 Merial Ltd Mixing units for chemical light ring of cells
WO2008085549A2 (en) * 2006-07-28 2008-07-17 Board Of Regents Of The University Of Texas System Compositions and methods for stimulation of lung innate immunity
RU2457848C2 (ru) * 2007-03-05 2012-08-10 Ом Фарма Бактериальный экстракт против расстройств пищеварительного или мочевого тракта и способ его получения
SI2114421T1 (en) 2007-03-05 2018-04-30 Om Pharma A bacterial extract for respiratory disorders and a process for its preparation
FR2923491B1 (fr) * 2007-11-14 2012-12-14 Deinove Sa Utilisation de bacteries pour la production de sources de bioenergie
GB0818453D0 (en) * 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
ES2356883B1 (es) 2008-07-24 2012-02-22 Bcn Peptides, S.A. Composición para el tratamiento del dolor y/o la inflamación.
BRPI0822997A2 (pt) * 2008-09-04 2015-06-23 Om Pharma Extratos imunomoduladores de bactérias lactobacillus e métodos para fabricação e uso dos mesmos
RU2425691C1 (ru) 2010-07-15 2011-08-10 ВАКЕ спол с.р.о. Аэрозольный препарат на основе апротинина для лечения вирусных респираторных инфекций
US9132243B2 (en) * 2010-07-23 2015-09-15 Tannermedico A/S Method of administering a substance to the throat
CN101979541A (zh) * 2010-10-28 2011-02-23 徐堤 一种快速共价闭合环状dna纯化试剂盒
CN103857398A (zh) * 2011-10-07 2014-06-11 安皮奥制药股份有限公司 鼻炎的治疗
MX2019006848A (es) * 2016-12-13 2019-10-07 Defensin Therapeutics Aps Metodos para tratar condiciones inflamatorias de los pulmones.

Also Published As

Publication number Publication date
IL286215B1 (en) 2025-04-01
CO2021013677A2 (es) 2021-10-20
IL286215B2 (en) 2025-08-01
WO2020182970A1 (en) 2020-09-17
ZA202106914B (en) 2023-10-25
JP2025176089A (ja) 2025-12-03
JP2022525177A (ja) 2022-05-11
MA55291A (fr) 2022-01-19
CN113840615A (zh) 2021-12-24
SG11202109937UA (en) 2021-10-28
US20210401902A1 (en) 2021-12-30
BR112021018006A2 (pt) 2021-11-16
EP3937957A1 (en) 2022-01-19
EP4721819A2 (en) 2026-04-08
EP4234026A2 (en) 2023-08-30
KR102922470B1 (ko) 2026-02-03
PE20212261A1 (es) 2021-11-29
IL286215A (en) 2021-10-31
US20250195587A1 (en) 2025-06-19
KR20210141546A (ko) 2021-11-23
AU2020235261A1 (en) 2021-09-16
CA3132564A1 (en) 2020-09-17
EP3937957B1 (en) 2026-05-06
EP4234026A3 (en) 2024-07-03
MX2021010912A (es) 2021-10-01
PH12021552089A1 (en) 2022-05-23
US11801271B2 (en) 2023-10-31
CR20210515A (es) 2022-03-28
US20230346855A1 (en) 2023-11-02
CL2021002401A1 (es) 2022-04-08

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