CU20240033A7 - Composiciones y métodos para la prevención y el tratamiento de la infección por el virus de la rabia - Google Patents

Composiciones y métodos para la prevención y el tratamiento de la infección por el virus de la rabia

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Publication number
CU20240033A7
CU20240033A7 CU2024000033A CU20240033A CU20240033A7 CU 20240033 A7 CU20240033 A7 CU 20240033A7 CU 2024000033 A CU2024000033 A CU 2024000033A CU 20240033 A CU20240033 A CU 20240033A CU 20240033 A7 CU20240033 A7 CU 20240033A7
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CU
Cuba
Prior art keywords
methods
virus infection
rabies virus
compositions
prevention
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Application number
CU2024000033A
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English (en)
Inventor
Parinaz Aliahmad
Andrew Geall
Shigeki Joseph Miyake-Stoner
Nathaniel Stephen Wang
Original Assignee
Replicate Bioscience Inc
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Publication date
Application filed by Replicate Bioscience Inc filed Critical Replicate Bioscience Inc
Publication of CU20240033A7 publication Critical patent/CU20240033A7/es

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
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    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20171—Demonstrated in vivo effect
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    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36161—Methods of inactivation or attenuation
    • C12N2770/36162—Methods of inactivation or attenuation by genetic engineering

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Abstract

<p>La presente divulgación se refiere en general al campo de la virología molecular, y en particular se refiere a las moléculas de ácido nucleico que codifican un genoma viral del virus alfavirus modificado o una construcción de ARN autorreplicante (srRNA), las células rcombinantes y las composiciones farmacéuticas que contienen el mismo, así como el uso de dichas moléculas de ácido nucleico, células recombinantes y composiciones para la producción de productos deseados en cultivos celulares o en un cuerpo vivo. Tambíen se proporcionan métodos para provocar una respuesta inmunitaria en un sujeto que la necesite, así como métodos para prevenir y/o tratar la infección por el virus de la rabia.</p>
CU2024000033A 2022-04-13 2023-04-12 Composiciones y métodos para la prevención y el tratamiento de la infección por el virus de la rabia CU20240033A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17/720,002 US11730804B1 (en) 2022-04-13 2022-04-13 Compositions and methods for the prevention and treatment of rabies virus infection
PCT/US2023/065677 WO2023201263A1 (en) 2022-04-13 2023-04-12 Compositions and methods for the prevention and treatment of rabies virus infection

Publications (1)

Publication Number Publication Date
CU20240033A7 true CU20240033A7 (es) 2025-06-11

Family

ID=87575492

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2024000033A CU20240033A7 (es) 2022-04-13 2023-04-12 Composiciones y métodos para la prevención y el tratamiento de la infección por el virus de la rabia

Country Status (16)

Country Link
US (2) US11730804B1 (es)
EP (1) EP4508066A1 (es)
JP (1) JP2025513827A (es)
KR (1) KR20250023343A (es)
CN (1) CN119487054A (es)
AU (1) AU2023254835A1 (es)
CA (1) CA3256261A1 (es)
CL (1) CL2024003076A1 (es)
CO (1) CO2024013755A2 (es)
CU (1) CU20240033A7 (es)
DO (1) DOP2024000204A (es)
IL (1) IL316175A (es)
MX (1) MX2024012693A (es)
PE (1) PE20250795A1 (es)
TW (1) TW202400800A (es)
WO (1) WO2023201263A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11058762B2 (en) * 2011-07-06 2021-07-13 Glaxosmithkline Biologicals Sa Immunogenic compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589533B1 (en) * 1997-09-18 2003-07-08 Research Development Foundation Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
PT1751289E (pt) * 2004-05-18 2009-03-31 Alphavax Inc Vectores de alfavirais derivados da tc-83, partículas e métodos
CN118490817A (zh) * 2017-11-06 2024-08-16 英特维特国际股份有限公司 狂犬病毒疫苗

Also Published As

Publication number Publication date
CO2024013755A2 (es) 2024-10-31
US20250186574A1 (en) 2025-06-12
CN119487054A (zh) 2025-02-18
TW202400800A (zh) 2024-01-01
MX2024012693A (es) 2025-02-10
EP4508066A1 (en) 2025-02-19
CA3256261A1 (en) 2023-10-19
DOP2024000204A (es) 2025-03-31
WO2023201263A1 (en) 2023-10-19
KR20250023343A (ko) 2025-02-18
AU2023254835A1 (en) 2024-10-24
CL2024003076A1 (es) 2025-04-25
PE20250795A1 (es) 2025-03-14
US11730804B1 (en) 2023-08-22
IL316175A (en) 2024-12-01
JP2025513827A (ja) 2025-04-30

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