CU22746A1 - Plásmido recombinante que contiene una secuencia nucleotídica de la proteína vp2 del virus de la enfermedad de la bursitis infecciosa o gumboro, la vacuna así obtenida y su tratamiento - Google Patents
Plásmido recombinante que contiene una secuencia nucleotídica de la proteína vp2 del virus de la enfermedad de la bursitis infecciosa o gumboro, la vacuna así obtenida y su tratamientoInfo
- Publication number
- CU22746A1 CU22746A1 CU1998161A CU1998161A CU22746A1 CU 22746 A1 CU22746 A1 CU 22746A1 CU 1998161 A CU1998161 A CU 1998161A CU 1998161 A CU1998161 A CU 1998161A CU 22746 A1 CU22746 A1 CU 22746A1
- Authority
- CU
- Cuba
- Prior art keywords
- sequence
- protein
- recombinant plasmid
- bursitis
- infectious
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 206010006811 Bursitis Diseases 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000002458 infectious effect Effects 0.000 title abstract 2
- 239000013612 plasmid Substances 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 108091007491 NSP3 Papain-like protease domains Proteins 0.000 abstract 1
- 101710194807 Protective antigen Proteins 0.000 abstract 1
- TXWRERCHRDBNLG-UHFFFAOYSA-N cubane Chemical compound C12C3C4C1C1C4C3C12 TXWRERCHRDBNLG-UHFFFAOYSA-N 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000003752 polymerase chain reaction Methods 0.000 abstract 1
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se obtuvo una secuencia nucleotídica de 490 pares de bases que codifica para la región hipervariable de la proteína VP2 del virus de la enfermedad de la Bursitis Infecciosa o Gumboro, a partir de un aislamiento cubano. Esta región contiene el principal antígeno protector contra este virus. El fragmento del genoma que porta esta secuencia fue amplificado por la técnica de la Reacción en Cadena de la Polimerasa y clonado en un vector de expresión en células de mamíferos y posteriormente encapsulado en vesículas lipídicas. el plásmido recombinante fue capaz de inducir respuesta inmunológica y protección contra la enfermedad en los animales vacunados, por vía parenteral.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU1998161A CU22746A1 (es) | 1998-11-02 | 1998-11-02 | Plásmido recombinante que contiene una secuencia nucleotídica de la proteína vp2 del virus de la enfermedad de la bursitis infecciosa o gumboro, la vacuna así obtenida y su tratamiento |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU1998161A CU22746A1 (es) | 1998-11-02 | 1998-11-02 | Plásmido recombinante que contiene una secuencia nucleotídica de la proteína vp2 del virus de la enfermedad de la bursitis infecciosa o gumboro, la vacuna así obtenida y su tratamiento |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU22746A1 true CU22746A1 (es) | 2002-02-28 |
Family
ID=46599382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU1998161A CU22746A1 (es) | 1998-11-02 | 1998-11-02 | Plásmido recombinante que contiene una secuencia nucleotídica de la proteína vp2 del virus de la enfermedad de la bursitis infecciosa o gumboro, la vacuna así obtenida y su tratamiento |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU22746A1 (es) |
-
1998
- 1998-11-02 CU CU1998161A patent/CU22746A1/es unknown
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