CU23175A1 - Formulacion liposomica de propionato de clobetasol - Google Patents
Formulacion liposomica de propionato de clobetasolInfo
- Publication number
- CU23175A1 CU23175A1 CU20000171A CU20000171A CU23175A1 CU 23175 A1 CU23175 A1 CU 23175A1 CU 20000171 A CU20000171 A CU 20000171A CU 20000171 A CU20000171 A CU 20000171A CU 23175 A1 CU23175 A1 CU 23175A1
- Authority
- CU
- Cuba
- Prior art keywords
- clobetasol propionate
- active ingredient
- liposomes
- formulation
- liposomic
- Prior art date
Links
- 229960004703 clobetasol propionate Drugs 0.000 title abstract 3
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000002502 liposome Substances 0.000 abstract 2
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se relaciona con una formulacion liposomica de propionato de clobetasol para uso topico para el tratamiento de enfermedades de la piel como dermatitis atopica y la psoriasis con excelente aspecto organolÉptico, muy buen efecto terapÉutico y favorable distribucion en el estrato corneo. Los liposomas incluyen el propionato de clobetasol como principio activo en bajas dosis. Estos liposomas son preferiblemente vesículas estables y multilamelares con un tamano medio entre 2000 - 5000 nm. La cantidad de principio activo es preferiblemente entre 0.02 y 0.025 %. La forma farmacÉutica del producto es preferiblemente jalea.
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20000171A CU23175A1 (es) | 2000-07-17 | 2000-07-17 | Formulacion liposomica de propionato de clobetasol |
| AT01953764T ATE339188T1 (de) | 2000-07-17 | 2001-07-17 | Liposomenformulierung mit clobetasol propionate |
| AU2001276254A AU2001276254B2 (en) | 2000-07-17 | 2001-07-17 | Liposomic formulation of clobetasol propionate |
| DE60123132T DE60123132T2 (de) | 2000-07-17 | 2001-07-17 | Liposomenformulierung mit clobetasol propionate |
| CNB018128955A CN100346773C (zh) | 2000-07-17 | 2001-07-17 | 丙酸氯倍他索的脂质体制剂 |
| MXPA03000207A MXPA03000207A (es) | 2000-07-17 | 2001-07-17 | Formulacion liposomica de propionato de clobetasol. |
| AU7625401A AU7625401A (en) | 2000-07-17 | 2001-07-17 | Liposomic formulation of clobetasol propionate |
| PCT/CU2001/000005 WO2002007702A2 (es) | 2000-07-17 | 2001-07-17 | Formulación liposómica de propionato de clobetasol |
| BR0112553-2A BR0112553A (pt) | 2000-07-17 | 2001-07-17 | Formulação lipossÈmica de propionato de clobetasol para aplicação tópica |
| CA002416731A CA2416731C (en) | 2000-07-17 | 2001-07-17 | Liposomal formulation of clobetasol propionate |
| HK05103910.6A HK1071070B (en) | 2000-07-17 | 2001-07-17 | Liposomic formulation of clobetasol propionate |
| EP01953764A EP1360958B1 (en) | 2000-07-17 | 2001-07-17 | Liposomic formulation of clobetasol propionate |
| ES01953764T ES2272508T3 (es) | 2000-07-17 | 2001-07-17 | Formulacion liposomica de propionato de clobetasol. |
| DK01953764T DK1360958T3 (da) | 2000-07-17 | 2001-07-17 | Liposomformulering af clobetasolpropionat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20000171A CU23175A1 (es) | 2000-07-17 | 2000-07-17 | Formulacion liposomica de propionato de clobetasol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23175A1 true CU23175A1 (es) | 2006-09-22 |
Family
ID=40134847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20000171A CU23175A1 (es) | 2000-07-17 | 2000-07-17 | Formulacion liposomica de propionato de clobetasol |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1360958B1 (es) |
| CN (1) | CN100346773C (es) |
| AT (1) | ATE339188T1 (es) |
| AU (2) | AU7625401A (es) |
| BR (1) | BR0112553A (es) |
| CA (1) | CA2416731C (es) |
| CU (1) | CU23175A1 (es) |
| DE (1) | DE60123132T2 (es) |
| DK (1) | DK1360958T3 (es) |
| ES (1) | ES2272508T3 (es) |
| MX (1) | MXPA03000207A (es) |
| WO (1) | WO2002007702A2 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
| JP5420128B2 (ja) | 1999-10-13 | 2014-02-19 | ジョンズ ホプキンス ユニバーシティ スクール オブ メディシン | ヘッジホッグ経路の調節物質、並びにそれに関する組成物及び利用法 |
| JP2004536045A (ja) * | 2001-07-02 | 2004-12-02 | タシ、シナン | 基底細胞癌及び他の腫瘍の治療におけるシクロパミンの使用方法 |
| EP1411938B1 (en) * | 2001-07-02 | 2005-07-06 | Tas, Sinan | Use of cyclopamine for the manufacture of a medicament for the treatemnt of psoriasis |
| WO2017037663A1 (en) | 2015-09-02 | 2017-03-09 | Cadila Healthcare Limited | Topical compositions comprising corticosteroids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
| US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| CA2129828A1 (en) * | 1992-02-12 | 1993-08-19 | Giovanni Lucchetti | Liposomal itraconazole formulations |
-
2000
- 2000-07-17 CU CU20000171A patent/CU23175A1/es not_active IP Right Cessation
-
2001
- 2001-07-17 AU AU7625401A patent/AU7625401A/xx active Pending
- 2001-07-17 WO PCT/CU2001/000005 patent/WO2002007702A2/es not_active Ceased
- 2001-07-17 CN CNB018128955A patent/CN100346773C/zh not_active Expired - Fee Related
- 2001-07-17 AU AU2001276254A patent/AU2001276254B2/en not_active Ceased
- 2001-07-17 MX MXPA03000207A patent/MXPA03000207A/es active IP Right Grant
- 2001-07-17 BR BR0112553-2A patent/BR0112553A/pt not_active Application Discontinuation
- 2001-07-17 ES ES01953764T patent/ES2272508T3/es not_active Expired - Lifetime
- 2001-07-17 DE DE60123132T patent/DE60123132T2/de not_active Expired - Lifetime
- 2001-07-17 DK DK01953764T patent/DK1360958T3/da active
- 2001-07-17 CA CA002416731A patent/CA2416731C/en not_active Expired - Fee Related
- 2001-07-17 EP EP01953764A patent/EP1360958B1/en not_active Expired - Lifetime
- 2001-07-17 AT AT01953764T patent/ATE339188T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1547465A (zh) | 2004-11-17 |
| CA2416731A1 (en) | 2003-01-16 |
| AU2001276254B2 (en) | 2006-07-13 |
| BR0112553A (pt) | 2003-06-24 |
| EP1360958A2 (en) | 2003-11-12 |
| WO2002007702A2 (es) | 2002-01-31 |
| AU7625401A (en) | 2002-02-05 |
| ES2272508T3 (es) | 2007-05-01 |
| EP1360958B1 (en) | 2006-09-13 |
| DE60123132D1 (de) | 2006-10-26 |
| CN100346773C (zh) | 2007-11-07 |
| DE60123132T2 (de) | 2007-04-12 |
| DK1360958T3 (da) | 2007-01-29 |
| ATE339188T1 (de) | 2006-10-15 |
| HK1071070A1 (zh) | 2005-07-08 |
| MXPA03000207A (es) | 2004-09-13 |
| CA2416731C (en) | 2009-12-15 |
| WO2002007702A3 (es) | 2003-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Lapse (for not paying fees) |