CU23711B7 - PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS. - Google Patents

PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS.

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Publication number
CU23711B7
CU23711B7 CU20080137A CU20080137A CU23711B7 CU 23711 B7 CU23711 B7 CU 23711B7 CU 20080137 A CU20080137 A CU 20080137A CU 20080137 A CU20080137 A CU 20080137A CU 23711 B7 CU23711 B7 CU 23711B7
Authority
CU
Cuba
Prior art keywords
derivatives used
kinases
alone
pharmaceutically acceptable
combination
Prior art date
Application number
CU20080137A
Other languages
Spanish (es)
Other versions
CU20080137A7 (en
Inventor
Xiahua Xin
Marion Wiesmann
Charles Voliva
Hanne Meritt
Mark Knapp
Thomas Hendrickson
Wendy Fantl
Edwin Iwanowicz
Paul Barsanti
Teresa Pick
Alicia Louie
Daniel Poon
Keith Pfister
Simon Ng
Allan Wagman
Yanchen Zhang
Joelle Verhagen
Aaron Smith
Kelly Frazier
Sarah Bartulis
Gordana Atallah
Sabina Pecchi
Zhi-Jie Ni
Matthew Burger
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to CU20080137A priority Critical patent/CU23711B7/en
Publication of CU20080137A7 publication Critical patent/CU20080137A7/en
Publication of CU23711B7 publication Critical patent/CU23711B7/en

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Abstract

Compuestos inhibidores de cinasa de fosfatidil-inositol (PI)-3 (I), sus sales farmaceúticamente aceptables y pro-farmacos de los mismos; composiciones de los nuevos compuestos, ya sean solos o en combinación con cuando menos un agente terapéutico adicional, con un vehículo farmacéuticamente aceptable; y usos de los nuevos compuestos, ya sea solos o en combinación con cuando menos un agente terapéutico adicional, en la profilaxis o el tratamiento de enfermedades proliferativas caracterizadas por la actividad anormal de los factores de crecimiento, cinasas de proetína serina/treonina, y cinasas de fosfolípido.Phosphatidyl inositol (PI) -3 (I) kinase inhibitor compounds, their pharmaceutically acceptable salts and pro-drugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, serine / threonine proetin kinases, and kinases phospholipid

CU20080137A 2008-07-17 2008-07-17 PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS. CU23711B7 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CU20080137A CU23711B7 (en) 2008-07-17 2008-07-17 PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20080137A CU23711B7 (en) 2008-07-17 2008-07-17 PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS.

Publications (2)

Publication Number Publication Date
CU20080137A7 CU20080137A7 (en) 2011-02-24
CU23711B7 true CU23711B7 (en) 2011-10-05

Family

ID=43734336

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20080137A CU23711B7 (en) 2008-07-17 2008-07-17 PIRIMIDINE DERIVATIVES USED AS PI-3 QUINASA INHIBITORS.

Country Status (1)

Country Link
CU (1) CU23711B7 (en)

Also Published As

Publication number Publication date
CU20080137A7 (en) 2011-02-24

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