CU23952B1 - PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORS - Google Patents
PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORSInfo
- Publication number
- CU23952B1 CU23952B1 CU2010000259A CU20100259A CU23952B1 CU 23952 B1 CU23952 B1 CU 23952B1 CU 2010000259 A CU2010000259 A CU 2010000259A CU 20100259 A CU20100259 A CU 20100259A CU 23952 B1 CU23952 B1 CU 23952B1
- Authority
- CU
- Cuba
- Prior art keywords
- derivatives
- quinasa
- inhibitors
- pirimidine derivatives
- pyrimidine derivatives
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 102100033793 ALK tyrosine kinase receptor Human genes 0.000 abstract 2
- 101710168331 ALK tyrosine kinase receptor Proteins 0.000 abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 2
- 102000013275 Somatomedins Human genes 0.000 abstract 2
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 2
- 150000003230 pyrimidines Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención proporciona novedosos derivados de pirimidina de la fórmula 1: y composiciones farmacéuticas de los mismos, y métodos para utilizar estos compuestos. Por ejemplo, los derivados de pirimidina de la invención se pueden utilizar para tratar, aminorar o prevenir una condición que responda a la inhibición del factor de crecimiento tipo insulina (IGF-1R) o de la cinasa de linfoma anaplásico (ALK).The invention provides novel pyrimidine derivatives of the formula 1: and pharmaceutical compositions thereof, and methods for using these compounds. For example, the pyrimidine derivatives of the invention can be used to treat, ameliorate or prevent a condition that responds to the inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15543409P | 2009-02-25 | 2009-02-25 | |
| PCT/US2009/048428 WO2010002655A2 (en) | 2008-06-25 | 2009-06-24 | Compounds and compositions as kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20100259A7 CU20100259A7 (en) | 2011-11-15 |
| CU23952B1 true CU23952B1 (en) | 2013-10-29 |
Family
ID=45000174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2010000259A CU23952B1 (en) | 2009-02-25 | 2010-12-23 | PIRIMIDINE DERIVATIVES AS QUINASA INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU23952B1 (en) |
-
2010
- 2010-12-23 CU CU2010000259A patent/CU23952B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CU20100259A7 (en) | 2011-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Lapse (for not paying fees) |