CU24323B1 - QUINOLIN Y QUINOXALINA DERIVADOS DE LA FÓRMULA (Ii), (Ij), (Ij'), (Ij'') y (Ij''') Y SALES DERIVADAS - Google Patents
QUINOLIN Y QUINOXALINA DERIVADOS DE LA FÓRMULA (Ii), (Ij), (Ij'), (Ij'') y (Ij''') Y SALES DERIVADASInfo
- Publication number
- CU24323B1 CU24323B1 CUP2015000027A CU20150027A CU24323B1 CU 24323 B1 CU24323 B1 CU 24323B1 CU P2015000027 A CUP2015000027 A CU P2015000027A CU 20150027 A CU20150027 A CU 20150027A CU 24323 B1 CU24323 B1 CU 24323B1
- Authority
- CU
- Cuba
- Prior art keywords
- derived
- formula
- quinoxalina
- quinolin
- sales
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940095064 tartrate Drugs 0.000 abstract 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- DTQVDTLACAAQTR-UHFFFAOYSA-M Trifluoroacetate Chemical compound [O-]C(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-M 0.000 abstract 1
- 229940072107 ascorbate Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 format Chemical compound 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
<p>Un compuesto de fórmula (I) o sales farmacéuticamente aceptables de los mismos, donde las sales farmacéuticamente aceptables son seleccionadas de hidrobromada, tartrato, citrato, trifluoroacetato, ascorbato, hidroclorido, tartrato, triflato, maleato, mesilato, formato, acetato y fumarato El cual es alternativamente seleccionado de entre un compuesto de fórmula Ii', Ij, Ij', Ij", Ij"'</p>
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18654409P | 2009-06-12 | 2009-06-12 | |
| EP20090305540 EP2266972A1 (en) | 2009-06-12 | 2009-06-12 | New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies |
| PCT/IB2010/052652 WO2010143170A2 (en) | 2009-06-12 | 2010-06-14 | Compounds useful for treating premature aging and in particular progeria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20150027A7 CU20150027A7 (es) | 2015-11-27 |
| CU24323B1 true CU24323B1 (es) | 2018-02-08 |
Family
ID=55659614
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000027A CU24323B1 (es) | 2009-06-12 | 2010-06-14 | QUINOLIN Y QUINOXALINA DERIVADOS DE LA FÓRMULA (Ii), (Ij), (Ij'), (Ij'') y (Ij''') Y SALES DERIVADAS |
| CUP2015000028A CU24319B1 (es) | 2009-06-12 | 2010-06-14 | QUINOLIN-2-AMINA Y QUINOXALINA DERIVADOS DE LA FÓRMULA (Ik) y (Ip) Y SALES DERIVADAS |
| CUP2015000025A CU24322B1 (es) | 2009-06-12 | 2010-06-14 | QUINOLIN-2-AMINA DERIVADOS DE LA FÓRMULA (Ig) Y SALES DERIVADAS |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000028A CU24319B1 (es) | 2009-06-12 | 2010-06-14 | QUINOLIN-2-AMINA Y QUINOXALINA DERIVADOS DE LA FÓRMULA (Ik) y (Ip) Y SALES DERIVADAS |
| CUP2015000025A CU24322B1 (es) | 2009-06-12 | 2010-06-14 | QUINOLIN-2-AMINA DERIVADOS DE LA FÓRMULA (Ig) Y SALES DERIVADAS |
Country Status (1)
| Country | Link |
|---|---|
| CU (3) | CU24323B1 (es) |
-
2010
- 2010-06-14 CU CUP2015000027A patent/CU24323B1/es unknown
- 2010-06-14 CU CUP2015000028A patent/CU24319B1/es unknown
- 2010-06-14 CU CUP2015000025A patent/CU24322B1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CU24322B1 (es) | 2018-02-08 |
| CU20150028A7 (es) | 2015-11-27 |
| CU20150025A7 (es) | 2015-11-27 |
| CU20150027A7 (es) | 2015-11-27 |
| CU24319B1 (es) | 2018-02-08 |
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