CU34329A - DERIVATIVES OF TIACINA - Google Patents
DERIVATIVES OF TIACINAInfo
- Publication number
- CU34329A CU34329A CU34329A CU34329A CU34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A
- Authority
- CU
- Cuba
- Prior art keywords
- lower alkyl
- optionally substituted
- same meaning
- general formula
- derivatives
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 150000004897 thiazines Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedimiento para la preparación de derivados de tiacina de la formula general: En la cual R1 significa alquilo inferior, R2 significa el radical de un heterociclo aromático con 1 a 3 heteroátomos, eventualmente substituidos por uno o dos grupos alquílicos inferiores o bien un radical fenílico, eventualmente sustituidos por halógeno, por alquilo inferior, por trifluorometilo o por alcoxilo inferior y R3 y R4 significan cada uno hidrógeno o alquilo inferior, caracterizado por hacerse reaccionar un compuesto de la formula II En la que R significa alquilo inferior, mientras que R1, R3 y R4 tienen el mismo significado que antes, con una amina de la formula general En la que R2 tiene el mismo significado que antes.Procedure for the preparation of thiazine derivatives of the general formula: In which R1 means lower alkyl, R2 means the radical of an aromatic heterocycle with 1 to 3 heteroatoms, optionally substituted by one or two lower alkyl groups or a phenyl radical, optionally substituted by halogen, by lower alkyl, by trifluoromethyl or by lower alkoxy and R3 and R4 each mean hydrogen or lower alkyl, characterized by reacting a compound of formula II In which R means lower alkyl, while R1, R3 and R4 have the same meaning as before, with an amine of the general formula Wherein R2 has the same meaning as before.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1158274A CH608500A5 (en) | 1974-08-26 | 1974-08-26 | Process for the preparation of thiazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU34329A true CU34329A (en) | 1980-10-30 |
Family
ID=4374870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU34329A CU34329A (en) | 1974-08-26 | 1975-08-21 | DERIVATIVES OF TIACINA |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE832707A (en) |
| CH (1) | CH608500A5 (en) |
| CU (1) | CU34329A (en) |
| MX (1) | MX160332A (en) |
| ZA (1) | ZA755055B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69027594T2 (en) * | 1989-11-30 | 1996-10-31 | Nippon Hypox Lab Inc | A MEDICINE CONTAINING THIAZINE DIOXIDE DERIVATIVE |
-
1974
- 1974-08-26 CH CH1158274A patent/CH608500A5/en not_active IP Right Cessation
-
1975
- 1975-08-05 ZA ZA00755055A patent/ZA755055B/en unknown
- 1975-08-21 CU CU34329A patent/CU34329A/en unknown
- 1975-08-25 BE BE159429A patent/BE832707A/en not_active IP Right Cessation
- 1975-08-25 MX MX1051A patent/MX160332A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE832707A (en) | 1976-02-25 |
| ZA755055B (en) | 1976-07-28 |
| CH608500A5 (en) | 1979-01-15 |
| MX160332A (en) | 1993-08-01 |
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