CY1114111T1 - Μεθοδοι χρησης του mirna για την ανιχνευση του in vivo θανατου των κυτταρων - Google Patents

Μεθοδοι χρησης του mirna για την ανιχνευση του in vivo θανατου των κυτταρων

Info

Publication number
CY1114111T1
CY1114111T1 CY20131100546T CY131100546T CY1114111T1 CY 1114111 T1 CY1114111 T1 CY 1114111T1 CY 20131100546 T CY20131100546 T CY 20131100546T CY 131100546 T CY131100546 T CY 131100546T CY 1114111 T1 CY1114111 T1 CY 1114111T1
Authority
CY
Cyprus
Prior art keywords
cell death
methods
vivo cell
mirna
detect
Prior art date
Application number
CY20131100546T
Other languages
English (en)
Inventor
Eugene M Shekhtman
Hovsep S Melkonyan
Samuil R Umansky
Vladimir S Scheinker
Original Assignee
Trovagene, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40378881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1114111(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trovagene, Inc. filed Critical Trovagene, Inc.
Publication of CY1114111T1 publication Critical patent/CY1114111T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Περιγράφονται μη-επεμβατικές μέθοδοι ανίχνευσης του in vivo θανάτου των κυττάρων μετρώντας τα επίπεδα του πανταχού παρόντος και ειδικού των ιστών miRΝΑ. Η μέθοδος μπορεί να εφαρμοστεί για την ανίχνευση παθολογιών που προκαλούνται ή συνοδεύονται από θάνατο των κυττάρων, ως επίσης και για την διάγνωση λοιμώδους πάθησης, κυτταροτοξικών επιδράσεων που επάγονται από διαφορετικούς χημικούς ή φυσικούς συντελεστές (παράγοντες), και από την παρουσία ειδικών εμβρυϊκών μη-φυσιολογικών ευρημάτων.
CY20131100546T 2007-08-22 2013-07-03 Μεθοδοι χρησης του mirna για την ανιχνευση του in vivo θανατου των κυτταρων CY1114111T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96587107P 2007-08-22 2007-08-22
EP08795523.3A EP2195450B2 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death

Publications (1)

Publication Number Publication Date
CY1114111T1 true CY1114111T1 (el) 2016-07-27

Family

ID=40378881

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100546T CY1114111T1 (el) 2007-08-22 2013-07-03 Μεθοδοι χρησης του mirna για την ανιχνευση του in vivo θανατου των κυτταρων

Country Status (16)

Country Link
US (4) US8486626B2 (el)
EP (2) EP2612926B1 (el)
JP (1) JP5416110B2 (el)
CN (2) CN101861399B (el)
AU (2) AU2008289447B2 (el)
CA (1) CA2696403C (el)
CY (1) CY1114111T1 (el)
DK (2) DK2612926T3 (el)
ES (2) ES2660785T3 (el)
HR (1) HRP20130618T1 (el)
HU (1) HUE019019T5 (el)
NO (1) NO2612926T3 (el)
PL (2) PL2195450T3 (el)
PT (2) PT2612926T (el)
TR (1) TR201802758T4 (el)
WO (1) WO2009025852A2 (el)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2271931A4 (en) * 2008-04-25 2011-10-12 Merck Sharp & Dohme MICRO-RNA BIOMARKERS FOR TISSUE INJURIES
WO2010004562A2 (en) * 2008-07-09 2010-01-14 Rosetta Genomics Ltd. Methods and compositions for detecting colorectal cancer
EP2853601B1 (en) * 2008-07-18 2016-09-21 TrovaGene, Inc. Methods for PCR-based detection of "ultra short" nucleic acid sequences
CA2757711A1 (en) * 2009-04-14 2010-10-21 Merck Sharp & Dohme Corp. Microrna as a biomarker of pancreatic islet beta-cell engagement
CA2767616A1 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
ES2597554T3 (es) * 2009-11-04 2017-01-19 Diamir, Llc Métodos de utilización de micro-ARN de fluidos corporales para el diagnóstico y control del deterioro cognitivo leve
HUE052213T2 (hu) 2009-11-06 2021-04-28 Univ Leland Stanford Junior Grafitkilökõdés nem invazív diagnosztizálása szervátültetett betegekben
SG185544A1 (en) * 2010-05-14 2012-12-28 Fluidigm Corp Nucleic acid isolation methods
EP2699666B1 (en) 2011-04-18 2016-10-05 DiamiR, LLC miRNA-BASED UNIVERSAL SCREENING TEST (UST)
CN102188719B (zh) * 2011-05-12 2012-12-19 南方医科大学 EB病毒miR-BART3反义寡聚核苷酸在制备治疗鼻咽癌的药物中的应用
JP6154809B2 (ja) * 2011-06-27 2017-06-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 アルツハイマー病を示すマイクロｒｎａバイオマーカー
WO2013022953A2 (en) * 2011-08-08 2013-02-14 Eugenia Wang Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof
WO2013043922A1 (en) * 2011-09-22 2013-03-28 ImmuMetrix, LLC Compositions and methods for analyzing heterogeneous samples
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
CN104334742A (zh) * 2012-01-27 2015-02-04 利兰斯坦福青年大学董事会 解析和定量无细胞rna的方法
US20160289762A1 (en) 2012-01-27 2016-10-06 The Board Of Trustees Of The Leland Stanford Junior University Methods for profiliing and quantitating cell-free rna
US20140087964A1 (en) * 2012-09-24 2014-03-27 University Of Virginia Patent Foundation Compositions and methods for detecting aberrant regulation, expression, and levels of hgh
CN104903468B (zh) * 2012-11-16 2019-04-23 萨尔大学 用于帕金森氏病的新诊断MiRNA标志物
EP2733219B1 (en) 2012-11-16 2017-09-20 Siemens Aktiengesellschaft Diagnostic miRNA markers for Alzheimer
EP2733220B1 (en) 2012-11-16 2017-10-18 Siemens Aktiengesellschaft Novel miRNA as a diagnostic marker for Alzheimer's Disease
CN103045736B (zh) * 2012-12-20 2014-09-17 徐勇 唐氏综合征21号染色体miRNA差异表达图谱模型、构建方法及应用
CN103045596A (zh) * 2012-12-20 2013-04-17 徐勇 唐氏综合征21号染色体相关miRNA、基因、筛选方法和应用
EP2759602A1 (en) * 2013-01-25 2014-07-30 Charité - Universitätsmedizin Berlin Non-invasive prenatal genetic diagnostic methods
EP3611262B1 (en) 2013-03-15 2020-11-11 Lineage Biosciences, Inc. Methods of sequencing the immune repertoire
JP6930832B2 (ja) 2013-11-18 2021-09-01 ディアミール, エルエルシーDiamir, Llc パーキンソン病（ＰＤ）の検出およびモニタリングのための、体液からのｍｉＲＮＡを使用する方法
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
TWI895765B (zh) 2014-07-18 2025-09-01 香港中文大學 Dna混合物中之組織甲基化模式分析
CA2986036C (en) 2015-05-18 2022-07-26 Karius, Inc. Compositions and methods for enriching populations of nucleic acids
WO2017019751A1 (en) 2015-07-27 2017-02-02 The Johns Hopkins University Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: pcr and sequencing based process methods
US20180355346A1 (en) * 2015-09-11 2018-12-13 Corning Incorporated Compositions and methods for nucleic acid purification from blood samples
US10975436B2 (en) 2016-01-05 2021-04-13 Diamir, Llc Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders
US11149313B2 (en) 2016-03-21 2021-10-19 Diamir, Llc Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases
WO2018045359A1 (en) * 2016-09-02 2018-03-08 Karius, Inc. Detection and treatment of infection during pregnancy
EP3538095A4 (en) 2016-11-14 2020-06-17 Berg LLC Methods for treating parkinson's disease
CA3039685A1 (en) 2016-11-30 2018-06-07 The Chinese University Of Hong Kong Analysis of cell-free dna in urine and other samples
US10907211B1 (en) 2017-02-16 2021-02-02 Quantgene Inc. Methods and compositions for detecting cancer biomarkers in bodily fluids
US10781487B2 (en) 2017-07-24 2020-09-22 Diamir, Llc miRNA-based methods for detecting and monitoring aging
AU2020221278A1 (en) 2019-02-14 2021-08-05 Mirvie, Inc. Methods and systems for determining a pregnancy-related state of a subject
JP7389437B2 (ja) * 2019-10-29 2023-11-30 国立研究開発法人国立循環器病研究センター 脳梗塞治療支援システム
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856088A (en) 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5168039A (en) 1990-09-28 1992-12-01 The Board Of Trustees Of The University Of Arkansas Repetitive DNA sequence specific for mycobacterium tuberculosis to be used for the diagnosis of tuberculosis
US6020124A (en) 1992-04-27 2000-02-01 Trustees Of Dartmouth College Detection of soluble gene sequences in biological fluids
EP0710248B1 (de) 1993-07-20 1999-09-29 Roche Diagnostics GmbH Melanom-inhibierendes protein
WO1995004140A1 (en) 1993-07-28 1995-02-09 Akzo Nobel N.V. Process for isolating nucleic acid from gram positive microorganisms
DE69433425T2 (de) 1993-08-30 2004-10-07 Promega Corp Zusammensetzungen und verfahren zur reinigung von nukleinsäuren
US5631130A (en) 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
CA2192364C (en) 1994-06-09 2009-01-20 Hans De Beenhouwer Method for the detection of the antibiotic resistance spectrum of mycobacterium species
US5731150A (en) 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
US6492144B1 (en) 1997-05-30 2002-12-10 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US20020119478A1 (en) 1997-05-30 2002-08-29 Diagen Corporation Methods for detection of nucleic acid sequences in urine
DK0920539T3 (da) 1997-05-30 2006-07-24 Xenomics Fremgangsmåder til detektion af nukleinsyresekvenser i urin
US5962665A (en) 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US20060204989A1 (en) * 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US20040053264A1 (en) 2002-02-01 2004-03-18 Park Sung Sup Clinical panel assay using DNA chips
EP2290073A3 (en) * 2004-05-28 2011-08-31 Asuragen, Inc. Methods and compositions involving microRNA
ITRM20050067A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
ITRM20050068A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
EP2351857B1 (en) 2005-02-17 2014-10-29 TrovaGene, Inc. Compositions and methods for detecting pathogen specific nucleic acids in urine
WO2006089203A2 (en) 2005-02-17 2006-08-24 Istituto Nazionale Per Le Malattie Infettive Irccs Lazzaro Spallanzani Compositions and methods for detecting viral specific nucleic acids in urine
US20060292616A1 (en) * 2005-06-23 2006-12-28 U.S. Genomics, Inc. Single molecule miRNA-based disease diagnostic methods
DE102005059315A1 (de) * 2005-12-09 2007-06-14 Qiagen Gmbh Verfahren zur Anreicherung von kurzkettigen Nukleinsäuren
US20070202511A1 (en) * 2006-02-28 2007-08-30 Sigma-Aldrich Co. Methods and compositions for the rapid isolation of small RNA molecules
EP2853601B1 (en) 2008-07-18 2016-09-21 TrovaGene, Inc. Methods for PCR-based detection of "ultra short" nucleic acid sequences

Also Published As

Publication number Publication date
ES2660785T3 (es) 2018-03-26
EP2195450A2 (en) 2010-06-16
JP5416110B2 (ja) 2014-02-12
TR201802758T4 (tr) 2018-03-21
ES2415245T5 (es) 2016-12-23
DK2195450T4 (en) 2016-10-24
AU2014210676B2 (en) 2017-04-06
US20180135126A1 (en) 2018-05-17
US20200283851A1 (en) 2020-09-10
US8486626B2 (en) 2013-07-16
EP2612926A1 (en) 2013-07-10
HUE019019T5 (en) 2017-04-28
PL2195450T3 (pl) 2013-09-30
CA2696403A1 (en) 2009-02-26
WO2009025852A2 (en) 2009-02-26
AU2014210676A1 (en) 2014-08-28
DK2195450T3 (da) 2013-06-24
ES2415245T3 (es) 2013-07-24
CN105400868B (zh) 2021-03-26
PL2612926T3 (pl) 2018-07-31
DK2612926T3 (en) 2018-03-12
AU2008289447A1 (en) 2009-02-26
CN101861399A (zh) 2010-10-13
EP2612926B1 (en) 2017-11-29
NO2612926T3 (el) 2018-04-28
HRP20130618T1 (en) 2013-07-31
CN101861399B (zh) 2015-11-25
EP2195450B1 (en) 2013-04-03
EP2195450B2 (en) 2016-07-20
AU2008289447B2 (en) 2014-09-04
US20150197805A1 (en) 2015-07-16
JP2010536372A (ja) 2010-12-02
PT2612926T (pt) 2018-03-02
HK1218767A1 (zh) 2017-03-10
CA2696403C (en) 2018-01-02
WO2009025852A3 (en) 2009-05-07
US20090081640A1 (en) 2009-03-26
PT2195450E (pt) 2013-07-10
CN105400868A (zh) 2016-03-16

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