CY1124591T1 - Εμπλαστρο μετρησης αναλυτη - Google Patents

Εμπλαστρο μετρησης αναλυτη

Info

Publication number
CY1124591T1
CY1124591T1 CY20211100894T CY211100894T CY1124591T1 CY 1124591 T1 CY1124591 T1 CY 1124591T1 CY 20211100894 T CY20211100894 T CY 20211100894T CY 211100894 T CY211100894 T CY 211100894T CY 1124591 T1 CY1124591 T1 CY 1124591T1
Authority
CY
Cyprus
Prior art keywords
electrode
control
adc
analog input
dac
Prior art date
Application number
CY20211100894T
Other languages
English (en)
Inventor
Karl-Heinz Koelker
Frederic Wehowski
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of CY1124591T1 publication Critical patent/CY1124591T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0531—Measuring skin impedance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0443—Modular apparatus
    • A61B2560/045—Modular apparatus with a separable interface unit, e.g. for communication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Signal Processing (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Emergency Medicine (AREA)
  • Power Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Αποκαλύπτεται ένα έμπλαστρο μέτρησης αναλύτη για επεμβατική μέτρηση μιας συγκέντρωσης ενός αναλύτη, συγκεκριμένα της γλυκόζης. Το έμπλαστρο μέτρησης αναλύτη περιλαμβάνει έναν αισθητήρα με ένα ηλεκτρόδιο εργασίας (101), ένα αντίθετο ηλεκτρόδιο (103) και ένα ηλεκτρόδιο αναφοράς (102). Το έμπλαστρο περιλαμβάνει επλέον μία μονάδα ηλεκτρονικών με έναν μικροελεγκτή (1200) και μία μονάδα μέτρησης ρύματος. Ο μικροελεγκτής (1200) περιλαμβάνει μία έξοδο ελέγχου (DAC), μία πρώτη αναλογική είσοδο (ADC-1) και μία δεύτερη αναλογική είσοδο (ADC-2). Η έξοδος ελέγχου (DAC) είναι λειτουργικά συνδεδεμένη με ένα ηλεκτρόδιο ελέγχου, το οποίο ηλεκτρόδιο ελέγχου είναι είτε το ηλεκτρόδιο εργασίας (101) είτε το αντίθετο ηλεκτρόδιο (103). Η πρώτη αναλογική είσοδος (ADC-2) είναι λειτουργικά συνδεδεμένη με ένα ηλεκτρόδιο μέτρησης μέσω της μονάδας μέτρησης ρεύματος, όπου το ηλεκτρόδιο μέτρησης είναι είτε το ηλεκτρόδιο εργασίας (101) είτε το αντίθετο ηλεκτρόδιο (103). Η δεύτερη αναλογική είσοδος (ADC-1) είναι λειτουργικά συνδεδεμένη με το ηλεκτρόδιο αναφοράς (102). Ο μικροελεγκτής (1200) είναι διαμορφωμένος για να ελέγχει παρέχοντας μια τάση ελέγχου στην έξοδο ελέγχου (DAC), μια διαφορά δυναμικού μεταξύ του ηλεκτροδίου εργασίας (101) και του αντίθετου ηλεκτροδίου (103) ώστε αυτή να ισούται με μια προκαθορισμένη τάση πόλωσης.
CY20211100894T 2016-03-11 2021-10-14 Εμπλαστρο μετρησης αναλυτη CY1124591T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16159883.4A EP3216395B1 (en) 2016-03-11 2016-03-11 Analyte measuring patch

Publications (1)

Publication Number Publication Date
CY1124591T1 true CY1124591T1 (el) 2022-07-22

Family

ID=55646279

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100894T CY1124591T1 (el) 2016-03-11 2021-10-14 Εμπλαστρο μετρησης αναλυτη

Country Status (13)

Country Link
US (1) US11969245B2 (el)
EP (1) EP3216395B1 (el)
JP (1) JP6735853B2 (el)
CN (1) CN108697387B (el)
CA (1) CA3010763C (el)
CY (1) CY1124591T1 (el)
DK (1) DK3216395T3 (el)
ES (1) ES2894047T3 (el)
HU (1) HUE055923T2 (el)
PL (1) PL3216395T3 (el)
PT (1) PT3216395T (el)
RU (1) RU2694473C1 (el)
WO (1) WO2017153506A1 (el)

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US12109032B1 (en) 2017-03-11 2024-10-08 Biolinq Incorporated Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure
US11045142B1 (en) 2017-04-29 2021-06-29 Biolinq, Inc. Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry
US12599337B1 (en) 2017-08-08 2026-04-14 Biolinq Incorporated Method and system for confirmation of microneedle-based analyte-selective sensor insertion into viable tissue via electrical interrogation
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Also Published As

Publication number Publication date
JP6735853B2 (ja) 2020-08-05
WO2017153506A1 (en) 2017-09-14
US11969245B2 (en) 2024-04-30
PL3216395T3 (pl) 2021-12-27
PT3216395T (pt) 2021-10-15
CA3010763C (en) 2023-03-28
CN108697387A (zh) 2018-10-23
US20190029577A1 (en) 2019-01-31
EP3216395B1 (en) 2021-08-18
JP2019509865A (ja) 2019-04-11
ES2894047T3 (es) 2022-02-11
RU2694473C1 (ru) 2019-07-15
CA3010763A1 (en) 2017-09-14
EP3216395A1 (en) 2017-09-13
DK3216395T3 (da) 2021-10-25
HUE055923T2 (hu) 2022-01-28
CN108697387B (zh) 2022-01-04

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