CY1807A - Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones - Google Patents

Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones

Info

Publication number
CY1807A
CY1807A CY180795A CY180795A CY1807A CY 1807 A CY1807 A CY 1807A CY 180795 A CY180795 A CY 180795A CY 180795 A CY180795 A CY 180795A CY 1807 A CY1807 A CY 1807A
Authority
CY
Cyprus
Prior art keywords
5alpha
17beta
androst
monosubstituted
aza
Prior art date
Application number
CY180795A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21878727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1807(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY1807A publication Critical patent/CY1807A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CY180795A 1987-04-03 1995-09-08 Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones CY1807A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3480687A 1987-04-03 1987-04-03

Publications (1)

Publication Number Publication Date
CY1807A true CY1807A (en) 1995-09-08

Family

ID=21878727

Family Applications (1)

Application Number Title Priority Date Filing Date
CY180795A CY1807A (en) 1987-04-03 1995-09-08 Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones

Country Status (5)

Country Link
EP (1) EP0285382B1 (de)
CA (1) CA1302277C (de)
CY (1) CY1807A (de)
DE (1) DE3888994T2 (de)
HK (1) HK116494A (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0542802T3 (da) * 1990-08-10 1996-07-22 Upjohn Co Stimulering af hårvækst med kaliumkanalåbnere og 5alfa-reduktase-inhibitorer
HU212459B (en) * 1992-10-02 1996-06-28 Richter Gedeon Vegyeszet Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them
GB2274060A (en) * 1993-01-07 1994-07-13 Merck & Co Inc Treatment of patterned alopecia with 17ß-acyl-4-aza-5-androst-1-ene-3-ones and minoxidil
US5359071A (en) * 1993-03-12 1994-10-25 Merck & Co., Inc. 15-substituted 4-azasteroids
WO1994022900A1 (en) * 1993-04-02 1994-10-13 Ciba-Geigy Ag AZA-ANDROSTANE-17β-CARBOXAMIDES
TW369521B (en) * 1993-09-17 1999-09-11 Smithkline Beecham Corp Androstenone derivative
US5547957A (en) * 1993-10-15 1996-08-20 Merck & Co., Inc. Method of treating androgenic alopecia with 5-α reductase inhibitors
TW382595B (en) * 1993-10-15 2000-02-21 Merck & Co Inc Pharmaceutical composition for use in arresting and reversing androgenic alopecia
RU2173152C2 (ru) * 1993-10-15 2001-09-10 Мерк Энд Ко., Инк. Способ лечения андрогенной алопеции ингибиторами 5-альфа-редуктазы
AU700565B2 (en) * 1993-10-15 1999-01-07 Merck Sharp & Dohme Corp. 5-alpha-reductase inhibitor formulations
BR9407866A (pt) 1993-10-21 1996-10-29 Merck & Co Inc Composto processos para inibiçao de 5 -redufase ou isoenzimas da mesma paratratamento de condiçoes de acne vulgar alopécia androgènica hirsutismo feminino hiperplasia prostática benigna prostatite e para o tratamento e/ou prevençao do cancer da próstata para interrupçao e reversao de alopécia androgènica e promoçao do crescimento de cabelo em um mamifero e para inibiçao de conversao biossintética da testosterona para di-hidro- testosterona em um mamifero e composiçao farmacèutica
US5541322A (en) * 1994-10-14 1996-07-30 Glaxo Wellcome Inc. Synthesis of 6-azaandrostenones
US5656613A (en) * 1995-01-04 1997-08-12 Merck & Co., Inc. Treatment of hyperandrogenic conditions
WO1997011702A1 (en) * 1995-09-27 1997-04-03 Merck & Co., Inc. Method of preventing androgenetic alopecia with 5-alpha reductase inhibitors
IL124764A0 (en) * 1998-06-04 1999-01-26 Univ Ben Gurion Topical composition for treatment of baldness
MXPA04010408A (es) 2002-04-24 2005-02-17 Boehringer Ingelheim Pharma Combinacion farmaceutica para el tratamiento de hiperplasia prostatica benigna o para la prevencion a largo plazo de la retencion urinaria aguda.
HUE045608T2 (hu) * 2003-06-06 2020-01-28 Univ Texas Antimikrobiális öblítõoldatok
CA2737025C (en) 2008-09-27 2012-09-04 Jina Pharmaceuticals, Inc. Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527030B2 (en) * 1978-04-13 1983-02-10 Merck & Co., Inc. 4-aza-17-substituted-5a-androstan-3-ones
NZ211145A (en) * 1984-02-27 1988-10-28 Merck & Co Inc 4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions

Also Published As

Publication number Publication date
DE3888994D1 (de) 1994-05-19
EP0285382A2 (de) 1988-10-05
EP0285382B1 (de) 1994-04-13
CA1302277C (en) 1992-06-02
HK116494A (en) 1994-11-04
DE3888994T2 (de) 1994-11-03
EP0285382A3 (en) 1990-09-12

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