CY2140B1 - Ellipticine derivatives with antitumor activity - Google Patents

Ellipticine derivatives with antitumor activity

Info

Publication number: CY2140B1
Authority: CY; Cyprus
Prior art keywords: antitumor activity; ellipticine derivatives; alkyl; heterocycle; image
Prior art date: 1992-10-02

Application number

CY9900036A

Other languages

English (en)

Inventor

E Frbisagni

R Jasztold-Howorko

G Atassi

A Pierre

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-02

Filing date

1999-11-19

Publication date

2002-06-21

1999-11-19 Application filed by Servier Lab filed Critical Servier Lab

2002-06-21 Publication of CY2140B1 publication Critical patent/CY2140B1/xx

Links

230000000259 anti-tumor effect Effects 0.000 title abstract 2
CTSPAMFJBXKSOY-UHFFFAOYSA-N ellipticine Chemical class N1=CC=C2C(C)=C(NC=3C4=CC=CC=3)C4=C(C)C2=C1 CTSPAMFJBXKSOY-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000000623 heterocyclic group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Indole Compounds (AREA)

CY9900036A 1992-10-02 1999-11-19 Ellipticine derivatives with antitumor activity CY2140B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9211672A FR2696465B1 (fr)	1992-10-02	1992-10-02	Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
CY2140B1 true CY2140B1 (en)	2002-06-21

Family

ID=9434061

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY9900036A CY2140B1 (en)	1992-10-02	1999-11-19	Ellipticine derivatives with antitumor activity

Country Status (14)

Country	Link
US (2)	US5407940A (de)
EP (1)	EP0591058B1 (de)
JP (1)	JP2529082B2 (de)
AT (1)	ATE166875T1 (de)
AU (1)	AU660853B2 (de)
CA (1)	CA2107485C (de)
CY (1)	CY2140B1 (de)
DE (1)	DE69318920T2 (de)
DK (1)	DK0591058T3 (de)
ES (1)	ES2119874T3 (de)
FR (1)	FR2696465B1 (de)
GR (1)	GR3027772T3 (de)
NZ (1)	NZ248841A (de)
ZA (1)	ZA937308B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU666416B2 (en) *	1993-01-29	1996-02-08	Tanabe Seiyaku Co., Ltd.	Ellipticine derivative and process for preparing the same
FR2757858B1 (fr) *	1996-12-30	1999-01-29	Adir	Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2757859B1 (fr) *	1996-12-30	1999-01-29	Adir	Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2767132B1 (fr) *	1997-08-06	1999-09-10	Adir	Nouveaux composes de bis pyrido [4,3-b] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2338498C (en) *	1998-08-03	2009-05-19	Applied Research Systems Ars Holding N.V.	Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives
US6231894B1 (en)	1999-10-21	2001-05-15	Duke University	Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase
US6624317B1 (en)	2000-09-25	2003-09-23	The University Of North Carolina At Chapel Hill	Taxoid conjugates as antimitotic and antitumor agents
US6677450B2 (en)	2000-10-06	2004-01-13	Bristol-Myers Squibb Company	Topoisomerase inhibitors
US6610727B2 (en)	2000-10-06	2003-08-26	Bristol-Myers Squibb Company	Anhydro sugar derivatives of indolocarbazoles
US6653290B2 (en) *	2000-10-06	2003-11-25	Bristol-Myers Squibb Company	Tumor proliferation inhibitors
WO2002060867A2 (en) *	2001-01-29	2002-08-08	Insight Strategy And Marketing Ltd	Carbazole derivatives and their uses as heparanase inhibitors
KR20030085035A (ko)	2001-03-22	2003-11-01	브리스톨-마이어스스퀴브컴파니	토포아이소머라아제 ｉ 선택성 세포독성인돌로피롤로카바졸 당 유도체

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU666416B2 (en) *	1993-01-29	1996-02-08	Tanabe Seiyaku Co., Ltd.	Ellipticine derivative and process for preparing the same

1992
- 1992-10-02 FR FR9211672A patent/FR2696465B1/fr not_active Expired - Fee Related
1993
- 1993-10-01 DK DK93402395T patent/DK0591058T3/da active
- 1993-10-01 ES ES93402395T patent/ES2119874T3/es not_active Expired - Lifetime
- 1993-10-01 DE DE69318920T patent/DE69318920T2/de not_active Expired - Fee Related
- 1993-10-01 NZ NZ248841A patent/NZ248841A/en unknown
- 1993-10-01 ZA ZA937308A patent/ZA937308B/xx unknown
- 1993-10-01 JP JP5247081A patent/JP2529082B2/ja not_active Expired - Fee Related
- 1993-10-01 US US08/130,627 patent/US5407940A/en not_active Expired - Fee Related
- 1993-10-01 CA CA002107485A patent/CA2107485C/fr not_active Expired - Fee Related
- 1993-10-01 AU AU48727/93A patent/AU660853B2/en not_active Ceased
- 1993-10-01 AT AT93402395T patent/ATE166875T1/de not_active IP Right Cessation
- 1993-10-01 EP EP93402395A patent/EP0591058B1/de not_active Expired - Lifetime
1994
- 1994-07-21 US US08/278,269 patent/US5498611A/en not_active Expired - Fee Related
1998
- 1998-08-28 GR GR980401951T patent/GR3027772T3/el unknown
1999
- 1999-11-19 CY CY9900036A patent/CY2140B1/xx unknown

Also Published As

Publication number	Publication date
US5498611A (en)	1996-03-12
DE69318920T2 (de)	1999-01-21
FR2696465B1 (fr)	1994-12-23
FR2696465A1 (fr)	1994-04-08
CA2107485A1 (fr)	1994-04-03
ATE166875T1 (de)	1998-06-15
AU660853B2 (en)	1995-07-06
JP2529082B2 (ja)	1996-08-28
EP0591058B1 (de)	1998-06-03
HK1010051A1 (en)	1999-06-11
EP0591058A1 (de)	1994-04-06
CA2107485C (fr)	2001-02-27
DK0591058T3 (da)	1999-03-22
ZA937308B (en)	1994-04-22
GR3027772T3 (en)	1998-11-30
AU4872793A (en)	1994-04-14
US5407940A (en)	1995-04-18
DE69318920D1 (de)	1998-07-09
ES2119874T3 (es)	1998-10-16
JPH06211852A (ja)	1994-08-02
NZ248841A (en)	1995-02-24

Publication	Publication Date	Title
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
EP0562049A4 (en)	1994-09-28	Novel 4-arylpiperazines and 4-arylpiperidines
TW207533B (de)	1993-06-11
TW256835B (de)	1995-09-11
GR3027772T3 (en)	1998-11-30	Ellipticine derivatives with antitumor activity
TW223637B (de)	1994-05-11
DE69505470D1 (de)	1998-11-26	Pyrrolocarbazol
IL99106A0 (en)	1992-07-15	Novel tricyclic compound or salts thereof,method for producing the same and antimicrobial agent containing the same
IL118368A0 (en)	1996-09-12	N-oxide heteroaroyl derivatives
NZ260159A (en)	1995-01-27	N-bicyclic nitrogen compounds and medicaments
DE69115526D1 (de)	1996-02-01	2,4-Pyrimidindionderivate und diese enthaltende Arzneimittel
DE69330612D1 (de)	2001-09-20	Neue pyridon carbonsäure-derivate
EP0481756A3 (en)	1992-08-26	Benzamide derivatives
EP0601191A4 (en)	1994-08-17	Novel tetracyclic compound.
EP0571012A3 (de)	1995-04-12	Monoquaternäre 2,16-Bispiperidinglandrostanderivate.
ES2093051T3 (es)	1996-12-16	Purinil- y pirimidil-tetrahidrofuranos.
GR3022628T3 (en)	1997-05-31	Heterocyclic derivatives of alkoxyacrylates with fungicidal activity