CY2183B1 - Antiprotozoal cyclic tetrapeptides - Google Patents

Antiprotozoal cyclic tetrapeptides

Info

Publication number
CY2183B1
CY2183B1 CY0000043A CY0000043A CY2183B1 CY 2183 B1 CY2183 B1 CY 2183B1 CY 0000043 A CY0000043 A CY 0000043A CY 0000043 A CY0000043 A CY 0000043A CY 2183 B1 CY2183 B1 CY 2183B1
Authority
CY
Cyprus
Prior art keywords
antiprotozoal
cyclic tetrapeptides
tetrapeptides
cyclic
coccidiosis
Prior art date
Application number
CY0000043A
Other languages
English (en)
Inventor
Christine Lange Cannova
Anne W Dombrowski
Michael A Goetz
Sandra J Rattray
Sheo Bux Singh
Jon Polishook
Gerald F Bills
Joyce A Greene
Gary K Darland
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY2183B1 publication Critical patent/CY2183B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/77—Fusarium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CY0000043A 1994-07-27 2000-08-23 Antiprotozoal cyclic tetrapeptides CY2183B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28132594A 1994-07-27 1994-07-27
US08/447,664 US5620953A (en) 1994-07-27 1995-05-23 Antiprotozoal cyclic tetrapeptides

Publications (1)

Publication Number Publication Date
CY2183B1 true CY2183B1 (en) 2002-08-23

Family

ID=26960833

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0000043A CY2183B1 (en) 1994-07-27 2000-08-23 Antiprotozoal cyclic tetrapeptides

Country Status (9)

Country Link
US (2) US5620953A (de)
EP (1) EP0777683B1 (de)
JP (1) JPH10503368A (de)
AT (1) ATE189460T1 (de)
AU (1) AU687602B2 (de)
CA (1) CA2194999A1 (de)
CY (1) CY2183B1 (de)
DE (1) DE69514928T2 (de)
WO (1) WO1996003428A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5620953A (en) * 1994-07-27 1997-04-15 Merck & Co., Inc. Antiprotozoal cyclic tetrapeptides
US6110697A (en) * 1995-09-20 2000-08-29 Merck & Co., Inc. Histone deacetylase as target for antiprotozoal agents
US5922837A (en) * 1995-09-20 1999-07-13 Merck & Co., Inc. Antiprotozoal cyclic tetrapeptides
GB9903087D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Process
WO2001007042A1 (en) * 1999-07-23 2001-02-01 Merck & Co., Inc. Apicidin-derived cyclic tetrapeptides
US7018642B2 (en) * 2001-04-27 2006-03-28 The Procter & Gamble Company Compounds, compositions, and methods for controlling biofilms
EP3461488A1 (de) 2017-09-27 2019-04-03 Onxeo Kombination aus einem dbait-molekül und einem hdac-inhibitor zur behandlung von krebs
EP3461480A1 (de) 2017-09-27 2019-04-03 Onxeo Kombination von checkpoint-hemmern des dna-schädigungsantwort-zellzyklus und belinostat zur behandlung von krebs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2410658A1 (fr) * 1977-11-30 1979-06-29 Science Union & Cie Nouveau produit biologique d'origine fongique, son obtention et son application a la therapeutique
US4338303A (en) * 1980-02-04 1982-07-06 Albert Einstein College Of Medicine Of Yeshiva University Treatment of parasitic diseases
FR2503182A1 (fr) * 1981-04-07 1982-10-08 Biofarma Sa Nouvelle souche de fusarium utilisable pour la production d'antibiotiques
JPH0334991A (ja) * 1989-06-30 1991-02-14 Shionogi & Co Ltd 環状テトラペプチドおよびその製造法
CA2032559C (en) * 1989-12-28 2001-11-06 Kiyofumi Ishikawa Endothelin antagonistic cyclic pentapeptides
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
EP0537418B1 (de) * 1991-07-01 1998-05-13 Ahc Inc. Bacillus Bakterium und dessen Verwendung
US5300491A (en) * 1991-10-31 1994-04-05 Apothekernes Laboratorium A.S. Treatment of protozoal infection
US5620953A (en) * 1994-07-27 1997-04-15 Merck & Co., Inc. Antiprotozoal cyclic tetrapeptides

Also Published As

Publication number Publication date
JPH10503368A (ja) 1998-03-31
EP0777683B1 (de) 2000-02-02
ATE189460T1 (de) 2000-02-15
US5620953A (en) 1997-04-15
DE69514928D1 (de) 2000-03-09
WO1996003428A1 (en) 1996-02-08
DE69514928T2 (de) 2000-08-17
AU687602B2 (en) 1998-02-26
EP0777683A1 (de) 1997-06-11
CA2194999A1 (en) 1996-02-08
US5861375A (en) 1999-01-19
EP0777683A4 (de) 1997-08-27
AU3200495A (en) 1996-02-22

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