CY480A - 11beta-Halo-tetracycline-6,12 hemiketals - Google Patents

11beta-Halo-tetracycline-6,12 hemiketals

Info

Publication number
CY480A
CY480A CY48069A CY48069A CY480A CY 480 A CY480 A CY 480A CY 48069 A CY48069 A CY 48069A CY 48069 A CY48069 A CY 48069A CY 480 A CY480 A CY 480A
Authority
CY
Cyprus
Prior art keywords
hemiketals
11beta
tetracycline
halo
Prior art date
Application number
CY48069A
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27567787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY480(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US76441A external-priority patent/US2984686A/en
Application filed by Pfizer filed Critical Pfizer
Publication of CY480A publication Critical patent/CY480A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D23/00—Producing tubular articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L11/00—Hoses, i.e. flexible pipes
    • F16L11/04—Hoses, i.e. flexible pipes made of rubber or flexible plastics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY48069A 1960-05-23 1969-04-10 11beta-Halo-tetracycline-6,12 hemiketals CY480A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3123660A 1960-05-23 1960-05-23
US3841460A 1960-06-29 1960-06-29
US7287560A 1960-12-01 1960-12-01
US7285760A 1960-12-01 1960-12-01
US76441A US2984686A (en) 1960-12-19 1960-12-19 6-deoxy-6-demethyl-6-methylene-5-oxytetracyclines
US8705961A 1961-02-06 1961-02-06
US106146A US3200149A (en) 1960-05-23 1961-05-05 alpha-6-deoxytetracycline derivatives and process

Publications (1)

Publication Number Publication Date
CY480A true CY480A (en) 1969-04-10

Family

ID=27567787

Family Applications (4)

Application Number Title Priority Date Filing Date
CY36567A CY365A (en) 1960-05-23 1967-02-02 6-Methylene-tetracyclines and method of preparing same
CY36667A CY366A (en) 1960-05-23 1967-02-02 11a-Halo-6-methylenetetracyclines and method of preparing same
CY38167A CY381A (en) 1960-05-23 1967-03-08 Tetracycline derivatives
CY48069A CY480A (en) 1960-05-23 1969-04-10 11beta-Halo-tetracycline-6,12 hemiketals

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CY36567A CY365A (en) 1960-05-23 1967-02-02 6-Methylene-tetracyclines and method of preparing same
CY36667A CY366A (en) 1960-05-23 1967-02-02 11a-Halo-6-methylenetetracyclines and method of preparing same
CY38167A CY381A (en) 1960-05-23 1967-03-08 Tetracycline derivatives

Country Status (10)

Country Link
US (1) US3200149A (en)
CH (3) CH459189A (en)
CY (4) CY365A (en)
DE (3) DE1300934B (en)
FI (1) FI40534B (en)
FR (1) FR1430859A (en)
GB (4) GB998294A (en)
MY (4) MY6700048A (en)
OA (1) OA00136A (en)
SE (1) SE302119B (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US4089900A (en) * 1967-09-13 1978-05-16 Pfizer Inc. Antimicrobial agents
DE1767891C3 (en) * 1968-06-28 1980-10-30 Pfizer Process for the preparation of aqueous medicinal solutions for parenteral, peroral and local use containing a tetracycline derivative
BR6915425D0 (en) * 1969-06-27 1973-01-16 Farmaceutici Italia PREPARATION OF CHLORINE-METHYLENE-TETRACYCLINE
BE754596A (en) * 1969-08-08 1971-02-08 Farmaceutici Italia METHYLENETETRACYCLINE ESTERS AND PROCESS FOR THEIR MANUFACTURE
BE755678R (en) * 1969-09-04 1971-03-03 Farmaceutici Italia METHYLENETETRACYCLINE ESTERS AND PROCESS FOR THEIR MANUFACTURE
DK153393C (en) * 1970-07-03 1988-11-28 Ivan Villax METHOD OF PREPARING METACYCLINE BY DEHALOGENING AN ACID ADDITION SALT OF 11A-CHLORO-6-DESOXY-6-DEMETHYL-6-METHYLENE-5-HYDROXYTETRACYCLINE
US3795707A (en) * 1970-12-28 1974-03-05 Rachelle Labor Italia Spa Manufacture of alpha-6-deoxytetracyclines
CH579531A5 (en) * 1972-02-24 1976-09-15 Ankerfarm Spa
US3954862A (en) * 1973-04-20 1976-05-04 Pfizer Inc. Process for producing α-6-deoxytetracyclines
GB1459861A (en) * 1973-06-21 1976-12-31 Pfizer Process for 11a-dehalogenation of 11a-halotetracyclines
US3907890A (en) * 1974-05-28 1975-09-23 Pfizer Preparation of alpha-6-deoxy-5-hydroxytetracycline
US4001321A (en) * 1975-06-26 1977-01-04 Pfizer Inc. Preparation of α-6-deoxytetracyclines
YU41480B (en) * 1979-03-12 1987-08-31 Pliva Pharm & Chem Works Process for obtaining alpha-6-deoxy-5-hydroxytetracycline
DK386784A (en) * 1983-08-17 1985-02-18 Hovione Int Ltd PROCEDURE FOR PREPARING ALFA-6-DESOXY-TETRACYCLINES
HU188367B (en) * 1983-09-02 1986-04-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing 6-demethy-6-deoxy-6-methylene-5-exytetracycline and 11a-chloro-derivative thereof
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (en) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd METHOD FOR PRODUCING ALPHA-6-DEOXYTETRACYCLINES.
US5281628A (en) * 1991-10-04 1994-01-25 American Cyanamid Company 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5328902A (en) * 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5442059A (en) * 1992-08-13 1995-08-15 American Cyanamid Company 9-[(substituted glycyl)amido)]-6-demethyl-6-deoxytetracyclines
US5284963A (en) * 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5420272A (en) * 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
SG47520A1 (en) * 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5371076A (en) * 1993-04-02 1994-12-06 American Cyanamid Company 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
US5538954A (en) * 1994-06-24 1996-07-23 A/S Dumex (Dumex Ltd.) Salts of tetracyclines
US20020123637A1 (en) * 1998-01-23 2002-09-05 Stuart B. Levy Pharmaceutically active compounds and methods of use thereof
EP1666454B1 (en) * 1999-09-14 2011-09-07 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
EP2311798A1 (en) * 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
CA2479877C (en) 2002-03-21 2012-08-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2003226112B9 (en) * 2002-03-29 2008-06-05 The Research Foundation Of State University Of New York Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
WO2005009943A2 (en) * 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
UA83266C2 (en) 2003-12-08 2008-06-25 Уайет Oxazole derivatives of tetracyclines
EP1848686A2 (en) 2005-02-15 2007-10-31 Wyeth 9-substituted tetracyclines
AR057324A1 (en) * 2005-05-27 2007-11-28 Wyeth Corp TIGECICLINE AND METHODS TO PREPARE 9-AMINOMINOCICLINE
AR057033A1 (en) * 2005-05-27 2007-11-14 Wyeth Corp TIGECICLINE AND METHODS TO PREPARE 9-NITROMINOCICLINE
AR057032A1 (en) * 2005-05-27 2007-11-14 Wyeth Corp TIGECICLINE AND PREPARATION METHODS
RU2008108215A (en) * 2005-08-31 2009-10-10 Вайет (Us) 9-AMINOCARBONYL SUBSTITUTED DERIVATIVES OF GLYCYCLICLINS
AP2657A (en) * 2007-03-23 2013-05-07 Molecular Res Ct Inc Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
PT2271348T (en) * 2008-03-28 2018-04-16 Paratek Pharm Innc FORMULATION OF ORAL TETRACYCIN COMPOUND TABLET
TW202332671A (en) * 2008-05-19 2023-08-16 美商Ｐｒｔｋ Ｓｐｖ２公司 Tosylate salts and polymorphs of a tetracycline compound
EP3135289B1 (en) 2010-05-12 2018-12-12 Rempex Pharmaceuticals, Inc. Tetracycline compositions
CN101967108B (en) * 2010-09-13 2013-06-19 苏春华 Methacycline derivative
CN102086165B (en) * 2010-12-29 2013-06-19 开封制药(集团)有限公司 Application of Pd catalyst in hydrogenation process for producing doxycycline
PT108978B (en) 2015-11-24 2020-03-09 Hovione Farm S A TETRACYCLINE SALTS
CN111732522B (en) * 2020-07-21 2022-10-18 山东国邦药业有限公司 Preparation method of doxycycline
WO2023205787A1 (en) * 2022-04-22 2023-10-26 Mork Benjamin V Compositions and methods for remediation using dithionite and activated carbons

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE565025A (en) *
BE566456A (en) *
BE572236A (en) *
BE572584A (en) *
DE1073482B (en) * 1960-01-21 American Cyanamid Company New York N Y (V St A) \ertr Dr F Zumstem Dipl Chem Dr rer nat E Assmann und Dipl Chem Dr R Koe nigsberger Pat Anwalte München 2 Process for the preparation of tetracyclines and their 5a epimers
DE932670C (en) * 1952-10-23 1955-09-05 Pfizer & Co C Process for the preparation of tetracycline and its salts
DE1011417B (en) * 1954-01-15 1957-07-04 Pfizer & Co C Process for the production of anhydrodesdimethylaminochlortetracycline or anhydrodesdimethylaminotetracycline
US2731497A (en) * 1954-05-14 1956-01-17 American Cyanamid Co Production of tetracycline
DE1131608B (en) * 1954-08-19 1962-06-14 Albert Fezer Suction fixture for workpieces, especially wooden panels
DE1007775B (en) * 1955-02-12 1957-05-09 Pfizer & Co C Process for the preparation of tetracycline and its salts
CH365484A (en) * 1956-05-28 1962-11-15 American Cyanamid Co Process for preparing an antibiotic substance
GB845649A (en) * 1957-03-01 1960-08-24 American Cyanamid Co 6-deoxytetracycline and 6-deoxyoxytetracycline
US3005023A (en) * 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US3036129A (en) * 1959-10-09 1962-05-22 American Cyanamid Co Preparation of 7-halo-6-deoxy-tetracyclines
DE1117567B (en) * 1959-02-26 1961-11-23 American Cyanamid Co Process for the production of 7- or 11ª ‡ -halogen- or 7, 11ª ‡ -dihalogen-6-deoxytetracyclines
DE1132918B (en) * 1959-04-16 1962-07-12 Hoechst Ag Process for the preparation of 12a-bromo-anhydrotetracyclines
US3019260A (en) * 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
US2976318A (en) * 1959-05-18 1961-03-21 Pfizer & Co C Tetracycline derivatives and process of producing the same

Also Published As

Publication number Publication date
DE1298522B (en) 1969-07-03
CY365A (en) 1967-02-02
GB995033A (en) 1965-06-10
DE1283834B (en) 1968-11-28
MY6700048A (en) 1967-12-31
US3200149A (en) 1965-08-10
OA00136A (en) 1966-03-15
FI40534B (en) 1968-11-30
SE302119B (en) 1968-07-08
MY6900209A (en) 1969-12-31
CH434238A (en) 1967-04-30
GB995032A (en) 1965-06-10
CH444853A (en) 1967-10-15
CY366A (en) 1967-02-02
FR1430859A (en) 1966-05-25
CY381A (en) 1967-03-08
DE1300934B (en) 1969-08-14
GB995031A (en)
GB998294A (en) 1965-07-14
CH459189A (en) 1968-07-15
MY7400226A (en) 1974-12-31
MY6700047A (en) 1967-12-31

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