CZ20021414A3 - Léčivo k terapii nebo profylaxi chorob podmíněných ischemickými stavy - Google Patents

Léčivo k terapii nebo profylaxi chorob podmíněných ischemickými stavy Download PDF

Info

Publication number: CZ20021414A3
Authority: CZ; Czechia
Prior art keywords: formula; medicament; use according; manufacture; compound
Prior art date: 1999-10-27

Application number

CZ20021414A

Other languages

Czech (cs)

English (en)

Inventor

Andreas Weichert

Udo Albus

Hans-Willi Jansen

Original Assignee

Aventis Pharma Deutschland Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-27

Filing date

2000-10-14

Publication date

2002-07-17

2000-10-14 Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh

2002-07-17 Publication of CZ20021414A3 publication Critical patent/CZ20021414A3/cs

Links

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TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 description 1
229960002965 pravastatin Drugs 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
238000009117 preventive therapy Methods 0.000 description 1
239000000047 product Substances 0.000 description 1
230000002062 proliferating effect Effects 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
239000003380 propellant Substances 0.000 description 1
230000004224 protection Effects 0.000 description 1
208000005069 pulmonary fibrosis Diseases 0.000 description 1
JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 description 1
239000003419 rna directed dna polymerase inhibitor Substances 0.000 description 1
239000012266 salt solution Substances 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
239000007921 spray Substances 0.000 description 1
235000000891 standard diet Nutrition 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000002600 sunflower oil Substances 0.000 description 1
239000002511 suppository base Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
208000011580 syndromic disease Diseases 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
230000002792 vascular Effects 0.000 description 1
230000009441 vascular protection Effects 0.000 description 1
210000004509 vascular smooth muscle cell Anatomy 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CZ20021414A 1999-10-27 2000-10-14 Léčivo k terapii nebo profylaxi chorob podmíněných ischemickými stavy CZ20021414A3 (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19951702A DE19951702A1 (de)	1999-10-27	1999-10-27	Verwendung von 2-Amino-3,4-dihydro-chinazolinen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten

Publications (1)

Publication Number	Publication Date
CZ20021414A3 true CZ20021414A3 (cs)	2002-07-17

Family

ID=7927021

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CZ20021414A CZ20021414A3 (cs)	1999-10-27	2000-10-14	Léčivo k terapii nebo profylaxi chorob podmíněných ischemickými stavy

Country Status (27)

Country	Link
US (1)	US6331546B1 (de)
EP (1)	EP1244454B1 (de)
JP (1)	JP2003512420A (de)
KR (1)	KR20020041831A (de)
CN (1)	CN1181822C (de)
AR (1)	AR026242A1 (de)
AT (1)	ATE324111T1 (de)
AU (1)	AU7664800A (de)
BR (1)	BR0014985A (de)
CA (1)	CA2388965A1 (de)
CZ (1)	CZ20021414A3 (de)
DE (2)	DE19951702A1 (de)
EE (1)	EE200200215A (de)
HR (1)	HRP20020363A2 (de)
HU (1)	HUP0203774A3 (de)
IL (1)	IL149160A0 (de)
MX (1)	MXPA02004035A (de)
NO (1)	NO20021710L (de)
NZ (1)	NZ518588A (de)
PL (1)	PL356399A1 (de)
RU (1)	RU2002113667A (de)
SK (1)	SK5582002A3 (de)
TR (1)	TR200201141T2 (de)
TW (1)	TWI227135B (de)
WO (1)	WO2001030328A2 (de)
YU (1)	YU30602A (de)
ZA (1)	ZA200204057B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000009070A2 (en) *	1998-08-13	2000-02-24	Hadasit Medical Research Services And Development Company Ltd.	Inhibition of pathogenic processes related to tissue trauma
EP1453810B1 (de) *	2001-12-05	2009-03-18	Sanofi-Aventis Deutschland GmbH	Substituierte 4-phenyltetrahydroisochinoline, verfahren zu ihrer herstellung, ihre verwendung als medikament, sowie sie enthaltendes medikament
DE10163914A1 (de) *	2001-12-22	2003-07-03	Aventis Pharma Gmbh	Substituierte 4-Phenyltetrahydroisochinolinium-Salze, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament
DE10312963A1 (de) *	2003-03-24	2004-10-07	Aventis Pharma Deutschland Gmbh	Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3560601A (en)	1968-11-25	1971-02-02	Ford Motor Co	Process for manufacturing porous thermoplastic sheet material
IL102764A0 (en) *	1991-08-16	1993-01-31	Merck & Co Inc	Quinazoline derivatives,and pharmaceutical compositions containing them
WO1994007498A1 (fr) *	1992-10-07	1994-04-14	Sumitomo Pharmaceuticals Company, Limited	Composition pharmaceutique utilisee pour inhiber la production des facteurs de necrose tumorale
DE19713427A1 (de) *	1997-04-01	1998-10-08	Hoechst Ag	Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

1999
- 1999-10-27 DE DE19951702A patent/DE19951702A1/de not_active Withdrawn
2000
- 2000-10-14 CN CNB008148872A patent/CN1181822C/zh not_active Expired - Fee Related
- 2000-10-14 CZ CZ20021414A patent/CZ20021414A3/cs unknown
- 2000-10-14 IL IL14916000A patent/IL149160A0/xx unknown
- 2000-10-14 JP JP2001532748A patent/JP2003512420A/ja not_active Abandoned
- 2000-10-14 KR KR1020027005359A patent/KR20020041831A/ko not_active Withdrawn
- 2000-10-14 AT AT00966165T patent/ATE324111T1/de not_active IP Right Cessation
- 2000-10-14 MX MXPA02004035A patent/MXPA02004035A/es active IP Right Grant
- 2000-10-14 WO PCT/EP2000/010127 patent/WO2001030328A2/de not_active Ceased
- 2000-10-14 CA CA002388965A patent/CA2388965A1/en not_active Abandoned
- 2000-10-14 RU RU2002113667/15A patent/RU2002113667A/ru not_active Application Discontinuation
- 2000-10-14 YU YU30602A patent/YU30602A/sh unknown
- 2000-10-14 AU AU76648/00A patent/AU7664800A/en not_active Abandoned
- 2000-10-14 HU HU0203774A patent/HUP0203774A3/hu unknown
- 2000-10-14 NZ NZ518588A patent/NZ518588A/en unknown
- 2000-10-14 EE EEP200200215A patent/EE200200215A/xx unknown
- 2000-10-14 PL PL00356399A patent/PL356399A1/xx unknown
- 2000-10-14 SK SK558-2002A patent/SK5582002A3/sk unknown
- 2000-10-14 HR HR20020363A patent/HRP20020363A2/hr not_active Application Discontinuation
- 2000-10-14 DE DE50012667T patent/DE50012667D1/de not_active Expired - Lifetime
- 2000-10-14 EP EP00966165A patent/EP1244454B1/de not_active Expired - Lifetime
- 2000-10-14 BR BR0014985-3A patent/BR0014985A/pt not_active IP Right Cessation
- 2000-10-14 TR TR2002/01141T patent/TR200201141T2/xx unknown
- 2000-10-24 TW TW089122279A patent/TWI227135B/zh not_active IP Right Cessation
- 2000-10-25 AR ARP000105620A patent/AR026242A1/es unknown
- 2000-10-26 US US09/696,233 patent/US6331546B1/en not_active Expired - Fee Related
2002
- 2002-04-11 NO NO20021710A patent/NO20021710L/no not_active Application Discontinuation
- 2002-05-22 ZA ZA200204057A patent/ZA200204057B/en unknown

Also Published As

Publication number	Publication date
WO2001030328A2 (de)	2001-05-03
HUP0203774A2 (en)	2003-05-28
ATE324111T1 (de)	2006-05-15
CA2388965A1 (en)	2001-05-03
NZ518588A (en)	2004-06-25
HUP0203774A3 (en)	2003-07-28
WO2001030328A3 (de)	2002-06-20
CN1181822C (zh)	2004-12-29
YU30602A (sh)	2004-12-31
ZA200204057B (en)	2003-02-26
PL356399A1 (en)	2004-06-28
MXPA02004035A (es)	2002-10-11
NO20021710D0 (no)	2002-04-11
AR026242A1 (es)	2003-02-05
BR0014985A (pt)	2003-07-22
AU7664800A (en)	2001-05-08
DE50012667D1 (de)	2006-06-01
KR20020041831A (ko)	2002-06-03
IL149160A0 (en)	2002-11-10
EP1244454B1 (de)	2006-04-26
NO20021710L (no)	2002-04-11
DE19951702A1 (de)	2001-05-03
RU2002113667A (ru)	2004-01-10
EP1244454A2 (de)	2002-10-02
JP2003512420A (ja)	2003-04-02
EE200200215A (et)	2003-06-16
HRP20020363A2 (en)	2004-02-29
HK1050480A1 (en)	2003-06-27
TR200201141T2 (tr)	2002-11-21
US6331546B1 (en)	2001-12-18
TWI227135B (en)	2005-02-01
CN1384747A (zh)	2002-12-11
SK5582002A3 (en)	2002-08-06

Publication	Publication Date	Title
CZ403392A3 (en)	1993-12-15	Amino-substituted benzylguanidines, process of their preparation, their use as medicaments and a medicament containing thereof
NO179673B (no)	1996-08-19	3,4,5-substituerte benzoylguanidiner og anvendelse av forbindelsene for fremstilling av legemidler
RU2160727C2 (ru)	2000-12-20	Бензоилгуанидины, способ их получения, промежуточное соединение для их получения, способ ингибирования и лекарственное средство
CZ20021414A3 (cs)	2002-07-17	Léčivo k terapii nebo profylaxi chorob podmíněných ischemickými stavy
CZ280896A3 (en)	1997-06-11	Substituted benzoylguanidines, process of their preparation, their use as a medicament or a diagnostic agent as well as medicaments containing such benzoylguanidines
JP4039589B2 (ja)	2008-01-30	置換インダニリジンアセチルグアニジン類、それらの製造方法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬
JPH0931045A (ja)	1997-02-04	４−フルオロアルキル−置換されたベンゾイルグアニジン、それらの製造法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬
US6291502B1 (en)	2001-09-18	Use of 2-imidazolyl-substituted carbinols for the production of a medicament for the treatment or phophylaxis of diseases caused by ischemic conditions
SK66997A3 (en)	1997-12-10	Substituted 1-naphtoylguanidines, producing method thereof, their use as a drug or diagnostic agent, as well as drug containing the same
SK282351B6 (sk)	2002-01-07	Orto-substituované benzoylguanidíny, spôsob ich výroby, ich použitie ako liečiva alebo diagnostického prostriedku a liečivo, ktoré ich obsahuje
US4148906A (en)	1979-04-10	Growth hormone inhibitors
JPH1081662A (ja)	1998-03-31	ビス−オルト−置換されたベンゾイルグアニジン、その製法、医薬または診断剤としてのその使用およびそれを含有する医薬
HK1050480B (en)	2005-05-06	Use of 2-amino-3, 4-dihydro-quinazolines for producing a medicament for treating or preventing diseases caused by ischaemic conditions
CZ293144B6 (cs)	2004-02-18	Ortho-substituované benzoylguanidiny, léčiva a prostředky, které je obsahují
CZ290041B6 (cs)	2002-05-15	Ortho-substituované benzoylguanidiny, způsob jejich přípravy, léčiva a prostředky, které je obsahují