DD131561A5 - Verfahren zur herstellung von 5-androsten-derivaten - Google Patents

Verfahren zur herstellung von 5-androsten-derivaten

Info

Publication number
DD131561A5
DD131561A5 DD7600200193A DD20019376A DD131561A5 DD 131561 A5 DD131561 A5 DD 131561A5 DD 7600200193 A DD7600200193 A DD 7600200193A DD 20019376 A DD20019376 A DD 20019376A DD 131561 A5 DD131561 A5 DD 131561A5
Authority
DD
German Democratic Republic
Prior art keywords
android
derivatives
preparation
android derivatives
Prior art date
Application number
DD7600200193A
Other languages
English (en)
Inventor
Alfred Weber
Mario Kennecke
Alfred Popper
Rudolf Mueller
Ulrich Eder
Gregor Haffer
Gerhard Sauer
Guenter Neef
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DD131561A5 publication Critical patent/DD131561A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/0025—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
    • C07J7/003—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DD7600200193A 1975-08-01 1976-07-30 Verfahren zur herstellung von 5-androsten-derivaten DD131561A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2534911A DE2534911C2 (de) 1975-08-01 1975-08-01 Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

Publications (1)

Publication Number Publication Date
DD131561A5 true DD131561A5 (de) 1978-07-05

Family

ID=5953265

Family Applications (3)

Application Number Title Priority Date Filing Date
DD7600200192A DD131562A5 (de) 1975-08-01 1976-07-30 Verfahren zur herstellung von 5-pregnen-derivaten
DD7600200193A DD131561A5 (de) 1975-08-01 1976-07-30 Verfahren zur herstellung von 5-androsten-derivaten
DD194155A DD127114A5 (de) 1975-08-01 1976-07-30

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD7600200192A DD131562A5 (de) 1975-08-01 1976-07-30 Verfahren zur herstellung von 5-pregnen-derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD194155A DD127114A5 (de) 1975-08-01 1976-07-30

Country Status (17)

Country Link
US (1) US4170518A (de)
JP (1) JPS5238090A (de)
AT (1) AT361639B (de)
BE (1) BE844745A (de)
CH (1) CH624415A5 (de)
CS (1) CS191981B2 (de)
DD (3) DD131562A5 (de)
DE (1) DE2534911C2 (de)
DK (1) DK140172C (de)
FR (1) FR2319650A1 (de)
GB (1) GB1576129A (de)
HU (1) HU183019B (de)
IE (1) IE44308B1 (de)
IT (1) IT1065955B (de)
NL (1) NL7608540A (de)
SE (1) SE420731B (de)
SU (1) SU697053A3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2632677A1 (de) * 1976-07-16 1978-01-26 Schering Ag Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
EP0680327B1 (de) * 1993-01-19 2004-09-15 Endorecherche Inc. Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
EP1149839A1 (de) * 2000-04-28 2001-10-31 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. Im wesentlichen von delta-14-pregnen-3,20-dion freiem Progesteron
KR100432054B1 (ko) * 2001-05-11 2004-05-17 (주)유진사이언스 스테롤로부터 4-안드로스텐-3,17-디온/안드로스타-1,4-디엔-3,17-디온으로의 뛰어난 전환능을 가지는 미생물 및 이의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione

Also Published As

Publication number Publication date
JPS5238090A (en) 1977-03-24
DK343976A (da) 1977-02-02
CH624415A5 (de) 1981-07-31
JPS6253160B2 (de) 1987-11-09
SU697053A3 (ru) 1979-11-05
DE2534911C2 (de) 1985-04-18
DD127114A5 (de) 1977-09-07
GB1576129A (en) 1980-10-01
DK140172C (da) 1979-11-26
SE7608575L (sv) 1977-02-02
DD131562A5 (de) 1978-07-05
ATA565676A (de) 1980-08-15
IE44308L (en) 1977-02-01
FR2319650A1 (fr) 1977-02-25
IT1065955B (it) 1985-03-04
BE844745A (fr) 1977-01-31
HU183019B (en) 1984-04-28
AT361639B (de) 1981-03-25
DE2534911A1 (de) 1977-02-17
CS191981B2 (en) 1979-07-31
DK140172B (da) 1979-07-02
SE420731B (sv) 1981-10-26
IE44308B1 (en) 1981-10-21
NL7608540A (nl) 1977-02-03
US4170518A (en) 1979-10-09
FR2319650B1 (de) 1980-05-09

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