DD144536A5 - Verfahren zur herstellung von arylbrenztraubensaeure - Google Patents

Verfahren zur herstellung von arylbrenztraubensaeure Download PDF

Info

Publication number: DD144536A5
Authority: DD; German Democratic Republic
Prior art keywords: acid; reaction; alcohol; items; bar
Prior art date: 1978-06-26

Application number

DD79213844A

Other languages

German (de)

English (en)

Inventor

Moustafa El-Chahawi

Original Assignee

Dynamit Nobel Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-26

Filing date

1979-06-22

Publication date

1980-10-22

1979-06-22 Application filed by Dynamit Nobel Ag filed Critical Dynamit Nobel Ag

1980-10-22 Publication of DD144536A5 publication Critical patent/DD144536A5/de

Links

238000000034 method Methods 0.000 title claims description 12
238000004519 manufacturing process Methods 0.000 title claims description 3
239000002253 acid Substances 0.000 title description 19
238000006243 chemical reaction Methods 0.000 claims description 19
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
-1 arylmethyl halides Chemical class 0.000 claims description 15
WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 claims description 14
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 claims description 9
101000588924 Anthopleura elegantissima Delta-actitoxin-Ael1a Proteins 0.000 claims description 8
UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 claims description 7
229910002091 carbon monoxide Inorganic materials 0.000 claims description 7
150000008044 alkali metal hydroxides Chemical class 0.000 claims description 6
150000007514 bases Chemical class 0.000 claims description 6
229910017052 cobalt Inorganic materials 0.000 claims description 5
239000010941 cobalt Substances 0.000 claims description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
229910001854 alkali hydroxide Inorganic materials 0.000 claims description 3
239000000203 mixture Substances 0.000 claims description 3
239000007864 aqueous solution Substances 0.000 claims description 2
WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 30
LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 20
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 16
BTNMPGBKDVTSJY-UHFFFAOYSA-N keto-phenylpyruvic acid Chemical compound OC(=O)C(=O)CC1=CC=CC=C1 BTNMPGBKDVTSJY-UHFFFAOYSA-N 0.000 description 15
229960003424 phenylacetic acid Drugs 0.000 description 15
239000003279 phenylacetic acid Substances 0.000 description 15
238000010626 work up procedure Methods 0.000 description 13
229940107700 pyruvic acid Drugs 0.000 description 11
239000002904 solvent Substances 0.000 description 10
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 9
239000001903 2-oxo-3-phenylpropanoic acid Substances 0.000 description 7
DEDGUGJNLNLJSR-UHFFFAOYSA-N alpha-hydroxycinnamic acid Natural products OC(=O)C(O)=CC1=CC=CC=C1 DEDGUGJNLNLJSR-UHFFFAOYSA-N 0.000 description 7
239000000243 solution Substances 0.000 description 7
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
150000007513 acids Chemical class 0.000 description 6
YFKBXYGUSOXJGS-UHFFFAOYSA-N 1,3-Diphenyl-2-propanone Chemical compound C=1C=CC=CC=1CC(=O)CC1=CC=CC=C1 YFKBXYGUSOXJGS-UHFFFAOYSA-N 0.000 description 4
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
150000001298 alcohols Chemical class 0.000 description 4
239000000706 filtrate Substances 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
229910052783 alkali metal Inorganic materials 0.000 description 3
125000003118 aryl group Chemical group 0.000 description 3
239000002585 base Substances 0.000 description 3
230000015572 biosynthetic process Effects 0.000 description 3
238000005810 carbonylation reaction Methods 0.000 description 3
239000003054 catalyst Substances 0.000 description 3
239000003153 chemical reaction reagent Substances 0.000 description 3
229910052751 metal Inorganic materials 0.000 description 3
239000002184 metal Substances 0.000 description 3
239000011541 reaction mixture Substances 0.000 description 3
239000007858 starting material Substances 0.000 description 3
238000003756 stirring Methods 0.000 description 3
150000003509 tertiary alcohols Chemical class 0.000 description 3
JQZAEUFPPSRDOP-UHFFFAOYSA-N 1-chloro-4-(chloromethyl)benzene Chemical compound ClCC1=CC=C(Cl)C=C1 JQZAEUFPPSRDOP-UHFFFAOYSA-N 0.000 description 2
RJTJVVYSTUQWNI-UHFFFAOYSA-N 2-ethylnaphthalene Chemical compound C1=CC=CC2=CC(CC)=CC=C21 RJTJVVYSTUQWNI-UHFFFAOYSA-N 0.000 description 2
MSXVEPNJUHWQHW-UHFFFAOYSA-N 2-methylbutan-2-ol Chemical compound CCC(C)(C)O MSXVEPNJUHWQHW-UHFFFAOYSA-N 0.000 description 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
239000003513 alkali Substances 0.000 description 2
150000001447 alkali salts Chemical class 0.000 description 2
239000006227 byproduct Substances 0.000 description 2
125000004432 carbon atom Chemical group C* 0.000 description 2
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 2
230000006315 carbonylation Effects 0.000 description 2
150000001805 chlorine compounds Chemical class 0.000 description 2
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 2
ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
239000000047 product Substances 0.000 description 2
CPRMKOQKXYSDML-UHFFFAOYSA-M rubidium hydroxide Chemical compound [OH-].[Rb+] CPRMKOQKXYSDML-UHFFFAOYSA-M 0.000 description 2
150000003333 secondary alcohols Chemical class 0.000 description 2
125000001424 substituent group Chemical group 0.000 description 2
MOBRMRJUKNQBMY-UHFFFAOYSA-N 1-(chloromethyl)-2-fluorobenzene Chemical compound FC1=CC=CC=C1CCl MOBRMRJUKNQBMY-UHFFFAOYSA-N 0.000 description 1
VQRBXYBBGHOGFT-UHFFFAOYSA-N 1-(chloromethyl)-2-methylbenzene Chemical compound CC1=CC=CC=C1CCl VQRBXYBBGHOGFT-UHFFFAOYSA-N 0.000 description 1
FYNVRRYQTHUESZ-UHFFFAOYSA-N 1-(chloromethyl)-3,5-dimethylbenzene Chemical compound CC1=CC(C)=CC(CCl)=C1 FYNVRRYQTHUESZ-UHFFFAOYSA-N 0.000 description 1
XBDXMDVEZLOGMC-UHFFFAOYSA-N 1-(chloromethyl)-3-fluorobenzene Chemical compound FC1=CC=CC(CCl)=C1 XBDXMDVEZLOGMC-UHFFFAOYSA-N 0.000 description 1
LZBOHNCMCCSTJX-UHFFFAOYSA-N 1-(chloromethyl)-3-methylbenzene Chemical compound CC1=CC=CC(CCl)=C1 LZBOHNCMCCSTJX-UHFFFAOYSA-N 0.000 description 1
IZXWCDITFDNEBY-UHFFFAOYSA-N 1-(chloromethyl)-4-fluorobenzene Chemical compound FC1=CC=C(CCl)C=C1 IZXWCDITFDNEBY-UHFFFAOYSA-N 0.000 description 1
DMHZDOTYAVHSEH-UHFFFAOYSA-N 1-(chloromethyl)-4-methylbenzene Chemical compound CC1=CC=C(CCl)C=C1 DMHZDOTYAVHSEH-UHFFFAOYSA-N 0.000 description 1
IATNZRYVIRYKDJ-UHFFFAOYSA-N 1-(chloromethyl)-4-phenoxybenzene Chemical class C1=CC(CCl)=CC=C1OC1=CC=CC=C1 IATNZRYVIRYKDJ-UHFFFAOYSA-N 0.000 description 1
XMWGTKZEDLCVIG-UHFFFAOYSA-N 1-(chloromethyl)naphthalene Chemical compound C1=CC=C2C(CCl)=CC=CC2=C1 XMWGTKZEDLCVIG-UHFFFAOYSA-N 0.000 description 1
DDVSFIUKWUTKES-UHFFFAOYSA-N 1-bromo-2-(chloromethyl)benzene Chemical compound ClCC1=CC=CC=C1Br DDVSFIUKWUTKES-UHFFFAOYSA-N 0.000 description 1
UDKGXKYEWBGQCG-UHFFFAOYSA-N 1-bromo-3-(chloromethyl)benzene Chemical compound ClCC1=CC=CC(Br)=C1 UDKGXKYEWBGQCG-UHFFFAOYSA-N 0.000 description 1
BSIIGUGKOPPTPZ-UHFFFAOYSA-N 1-bromo-4-(chloromethyl)benzene Chemical compound ClCC1=CC=C(Br)C=C1 BSIIGUGKOPPTPZ-UHFFFAOYSA-N 0.000 description 1
DDGRAFHHXYIQQR-UHFFFAOYSA-N 1-chloro-3-(chloromethyl)benzene Chemical compound ClCC1=CC=CC(Cl)=C1 DDGRAFHHXYIQQR-UHFFFAOYSA-N 0.000 description 1
GXXXUZIRGXYDFP-UHFFFAOYSA-N 2-(4-methylphenyl)acetic acid Chemical compound CC1=CC=C(CC(O)=O)C=C1 GXXXUZIRGXYDFP-UHFFFAOYSA-N 0.000 description 1
CDPKJZJVTHSESZ-UHFFFAOYSA-N 4-chlorophenylacetic acid Chemical compound OC(=O)CC1=CC=C(Cl)C=C1 CDPKJZJVTHSESZ-UHFFFAOYSA-N 0.000 description 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
DULCUDSUACXJJC-UHFFFAOYSA-N Ethyl phenylacetate Chemical compound CCOC(=O)CC1=CC=CC=C1 DULCUDSUACXJJC-UHFFFAOYSA-N 0.000 description 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
SSMBXPJYHMZLOJ-UHFFFAOYSA-N Isopropyl phenylacetate Chemical compound CC(C)OC(=O)CC1=CC=CC=C1 SSMBXPJYHMZLOJ-UHFFFAOYSA-N 0.000 description 1
CRZQGDNQQAALAY-UHFFFAOYSA-N Methyl benzeneacetate Chemical compound COC(=O)CC1=CC=CC=C1 CRZQGDNQQAALAY-UHFFFAOYSA-N 0.000 description 1
AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 1
206010035148 Plague Diseases 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
241000607479 Yersinia pestis Species 0.000 description 1
230000001476 alcoholic effect Effects 0.000 description 1
125000003545 alkoxy group Chemical group 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
125000005219 aminonitrile group Chemical group 0.000 description 1
KCXMKQUNVWSEMD-UHFFFAOYSA-N benzyl chloride Chemical compound ClCC1=CC=CC=C1 KCXMKQUNVWSEMD-UHFFFAOYSA-N 0.000 description 1
229940073608 benzyl chloride Drugs 0.000 description 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
229910052794 bromium Inorganic materials 0.000 description 1
150000001649 bromium compounds Chemical class 0.000 description 1
150000001728 carbonyl compounds Chemical class 0.000 description 1
150000003857 carboxamides Chemical class 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000001816 cooling Methods 0.000 description 1
125000004093 cyano group Chemical group *C#N 0.000 description 1
150000004292 cyclic ethers Chemical class 0.000 description 1
MQIKJSYMMJWAMP-UHFFFAOYSA-N dicobalt octacarbonyl Chemical group [Co+2].[Co+2].[O+]#[C-].[O+]#[C-].[O+]#[C-].[O+]#[C-].[O+]#[C-].[O+]#[C-].[O+]#[C-].[O+]#[C-] MQIKJSYMMJWAMP-UHFFFAOYSA-N 0.000 description 1
230000007613 environmental effect Effects 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000019634 flavors Nutrition 0.000 description 1
229910052731 fluorine Inorganic materials 0.000 description 1
239000011737 fluorine Substances 0.000 description 1
ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
229910052736 halogen Inorganic materials 0.000 description 1
150000002367 halogens Chemical class 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
239000011261 inert gas Substances 0.000 description 1
239000000543 intermediate Substances 0.000 description 1
150000004694 iodide salts Chemical class 0.000 description 1
239000007788 liquid Substances 0.000 description 1
125000006178 methyl benzyl group Chemical group 0.000 description 1
IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
239000003921 oil Substances 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
230000020477 pH reduction Effects 0.000 description 1
239000000575 pesticide Substances 0.000 description 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
150000003138 primary alcohols Chemical class 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
150000003254 radicals Chemical class 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DD79213844A 1978-06-26 1979-06-22 Verfahren zur herstellung von arylbrenztraubensaeure DD144536A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2828041A DE2828041C2 (de)	1978-06-26	1978-06-26	Verfahren zur Herstellung von Arylbrenztraubensäuren

Publications (1)

Publication Number	Publication Date
DD144536A5 true DD144536A5 (de)	1980-10-22

Family

ID=6042822

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD79213844A DD144536A5 (de)	1978-06-26	1979-06-22	Verfahren zur herstellung von arylbrenztraubensaeure

Country Status (13)

Country	Link
US (1)	US4447644A (it)
JP (1)	JPS554398A (it)
BE (1)	BE877229A (it)
BR (1)	BR7903978A (it)
CA (1)	CA1125307A (it)
CH (1)	CH644343A5 (it)
DD (1)	DD144536A5 (it)
DE (1)	DE2828041C2 (it)
FR (1)	FR2429772A1 (it)
GB (1)	GB2026478B (it)
IT (1)	IT1120442B (it)
MX (1)	MX149923A (it)
NL (1)	NL7904941A (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2629816A1 (fr) *	1988-04-06	1989-10-13	Rhone Poulenc Chimie	Procede de preparation de phenylpyruvate alcalin

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1139455B (it) *	1981-09-21	1986-09-24	Montedison Spa	Processo per la preparazione di acidi alfa-arilpropionici e loro sali alcalini
IT1198351B (it) *	1981-09-21	1988-12-21	Montedison Spa	Processo per la carbonilazione di alogenuri benzilici secondari
IT1140323B (it) *	1981-12-09	1986-09-24	Montedison Spa	Processo per la preparazione di composti carbossilati aromatici o etero-aromatici
US4738802A (en) *	1982-03-01	1988-04-19	Ethyl Corporation	Process for preparing alkyl α-keto-carboxylic acids from alkyl halides
US4492798A (en) *	1982-03-01	1985-01-08	Ethyl Corporation	Process for preparing arylalkylpyruvic acids
US4473706A (en) *	1982-08-06	1984-09-25	Ethyl Corporation	Preparation of cyclic-keto-acids
FR2535704B1 (fr) *	1982-11-05	1986-07-11	Rhone Poulenc Spec Chim	Procede d'obtention de cobalttetracarbonylates alcalins ou alcalino-terreux et de leurs solutions et leur application a la carbonylation de composes a groupes halogenomethyle
DE3374057D1 (en) *	1982-11-05	1987-11-19	Rhone Poulenc Chimie	Process for the preparation of alkaline earth cobalt teracarbonylates and their solutions,and their use in the carbonylation of compounds containing halogen methyl groups
EP0134216A4 (en) *	1983-01-13	1985-07-01	Ethyl Corp	METHOD FOR PRODUCING ALPHA KETO CARBONIC ACIDS.
US4481368A (en) *	1983-07-28	1984-11-06	Ethyl Corporation	Process for preparing α-keto-carboxylic acids from acyl halides
US4481369A (en) *	1983-07-28	1984-11-06	Ethyl Corporation	Preparation of α-keto-carboxylic acids from acyl halides
US4544505A (en) *	1983-10-21	1985-10-01	Ethyl Corporation	Preparation of halo-α-keto-carboxylic acids
DE3438439A1 (de) *	1983-10-26	1985-05-09	Daido Tokushuko K.K., Nagoya, Aichi	Pulveroberflaechenschweissverfahren
WO1985002180A1 (en) *	1983-11-14	1985-05-23	Ethyl Corporation	PREPARATION OF BIS-alpha-KETO-CARBOXYLIC ACIDS
WO1985002181A1 (en) *	1983-11-15	1985-05-23	Ethyl Corporation	Preparation of cyclic-keto-acids
EP0198828A4 (en) *	1983-12-13	1986-11-04	Commw Scient Ind Res Org	VACCINE AGAINST THE VIRUSES OF INFECTIOUS BURSAL DISEASE.
DE3345411A1 (de) *	1983-12-15	1985-06-27	Dynamit Nobel Ag, 5210 Troisdorf	Verfahren zur reindarstellung von carbonsaeuren
US4689431A (en) *	1985-02-21	1987-08-25	Japan As Represented By General Director Of Agency Of Industrial Science And Technology	Method for the preparation of phenyl pyruvic acid
FR2590565B1 (fr) *	1985-11-27	1988-01-08	Rhone Poulenc Spec Chim	Procede de preparation d'alpha-hydroxyacides
US4948920A (en) *	1989-03-24	1990-08-14	The Nutrasweet Company	Process for the preparation of phenylpyruvic acid from benzyl chloride
US10774036B2 (en)	2016-12-23	2020-09-15	Novartis Ag	Process for early sacubitril intermediates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL272335A (it) *	1960-12-08
DE2259072C3 (de) *	1972-12-02	1978-10-05	Dynamit Nobel Ag, 5210 Troisdorf	Verfahren zur Herstellung von Arylessigsäuren
GB1522721A (en) *	1975-01-09	1978-08-31	Rhone Poulenc Ind	Process for the carbonylation of aralkyl halides
US4351952A (en) *	1980-07-01	1982-09-28	Montedison S.P.A.	Process for preparing phenyl pyruvic acids

1978
- 1978-06-26 DE DE2828041A patent/DE2828041C2/de not_active Expired
1979
- 1979-03-27 MX MX177082A patent/MX149923A/es unknown
- 1979-06-22 DD DD79213844A patent/DD144536A5/de unknown
- 1979-06-22 FR FR7916170A patent/FR2429772A1/fr active Granted
- 1979-06-22 CA CA330,652A patent/CA1125307A/en not_active Expired
- 1979-06-25 NL NL7904941A patent/NL7904941A/xx not_active Application Discontinuation
- 1979-06-25 GB GB7922073A patent/GB2026478B/en not_active Expired
- 1979-06-25 BR BR7903978A patent/BR7903978A/pt unknown
- 1979-06-25 IT IT49532/79A patent/IT1120442B/it active
- 1979-06-25 CH CH592679A patent/CH644343A5/de not_active IP Right Cessation
- 1979-06-25 BE BE0/195931A patent/BE877229A/xx not_active IP Right Cessation
- 1979-06-26 JP JP7977279A patent/JPS554398A/ja active Pending
1982
- 1982-05-24 US US06/381,133 patent/US4447644A/en not_active Expired - Fee Related

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2629816A1 (fr) *	1988-04-06	1989-10-13	Rhone Poulenc Chimie	Procede de preparation de phenylpyruvate alcalin
EP0341099A1 (fr) *	1988-04-06	1989-11-08	Rhone-Poulenc Chimie	Procédé de préparation de phénylpyruvate alcalin

Also Published As

Publication number	Publication date
DE2828041A1 (de)	1980-01-03
CH644343A5 (de)	1984-07-31
FR2429772A1 (fr)	1980-01-25
FR2429772B1 (it)	1983-08-26
BR7903978A (pt)	1980-03-11
IT1120442B (it)	1986-03-26
US4447644A (en)	1984-05-08
GB2026478B (en)	1982-10-06
MX149923A (es)	1984-02-09
DE2828041C2 (de)	1984-05-10
CA1125307A (en)	1982-06-08
NL7904941A (nl)	1979-12-28
IT7949532A0 (it)	1979-06-25
JPS554398A (en)	1980-01-12
GB2026478A (en)	1980-02-06
BE877229A (fr)	1979-10-15

Publication	Publication Date	Title
DD144536A5 (de)	1980-10-22	Verfahren zur herstellung von arylbrenztraubensaeure
DE2733663C2 (it)	1988-09-15
DE2600541C3 (de)	1978-06-08	Verfahren zur Herstellung von Phenylbrenztraubensäure oder Arylbrenztraubensäuren
DE2259072A1 (de)	1974-06-20	Verfahren zur herstellung von arylessigsaeuren
DE2847241A1 (de)	1979-05-03	Verfahren zur herstellung von carbonsaeuren oder ihren estern
DE2801886A1 (de)	1978-07-20	Verfahren zur herstellung der alkalisalze der phenylessigsaeure
DE69516548T2 (de)	2000-08-10	Verfahren zur Herstellung von Cyclopropancarboxamid
DE2240398C3 (de)	1981-10-29	Verfahren zur Herstellung von Arylessigsäurealkylestern
DE68908073T2 (de)	1993-11-25	Kontinuierliches Verfahren zur Herstellung von Dialkylcarbonaten.
DE2359963C2 (de)	1982-01-28	Verfahren zur Herstellung von Malonsäuredialkylestern
EP0056154B1 (de)	1984-05-23	Verfahren zur Herstellung von 2,2-Dimethyl-3-vinyl-cyclopropancarbonsäuren und deren Estern
DD206371A5 (de)	1984-01-25	Verfahren zur herstellung eines 2s chiralen alkohols
EP0123187A2 (de)	1984-10-31	Verfahren zur Herstellung von fluorierten Phenylessigsäureestern und neue fluorierte Trichlorethylbenzole
DE2410782C2 (de)	1982-02-18	Phenylendiessigsäuredialkylester und Verfahren zu deren Herstellung
DE69719799T2 (de)	2003-09-18	Carbonsäure, mit beschleunigter bildung von diestern
EP0087585A1 (de)	1983-09-07	Verfahren zur Herstellung von 3-Alkoxi-acrylnitrilen
DE2436788C2 (de)	1982-09-23	Verfahren zur Herstellung von &alpha;, &beta;-ungesättigten Carbonsäureestern
DE2443142C2 (de)	1985-10-03	Verfahren zur Herstellung von Cyclopropancarbonsäurenitril
EP0057281B1 (de)	1984-10-17	Verfahren zur Herstellung von alpha-Hydroximethylenarylessigestern
DE3641605C2 (de)	1994-06-09	Verfahren zur Darstellung von Acetalen der Formylessigsäureester
DE2240399C3 (de)	1979-06-28	Verfahren zur Herstellung von Arylessigsäurealkylestem
DE2521610C2 (de)	1981-01-15	Verfahren zur Herstellung von Arylessigsäuren und deren Estern
EP0193801A2 (de)	1986-09-10	Verfahren zur kontinuierlichen Homologisierung von Methanol
DE2524389C2 (de)	1986-12-04	Verfahren zur Herstellung von Malonsäuredialkylestern
EP0103749B1 (de)	1986-07-02	Dialkoxymethyl-butyrolactone, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung